Acute nonlymphocytic leukemia (ANLL) has been recognized for several years as the most serious long-term complication of chemotherapy or radiotherapy or both in a number of malignant diseases, and it has often been reported in patients previously treated ...

Herpes zoster, a common infection in immunocompromised patients, can be life-threatening if the viscera become involved.^{1 2 3 4} As a consequence, herpes-zoster infections have become targets for experimental antiviral trials. In 1976, we reported the ...

The Hypertension Detection and Follow-up Program was designed to determine whether total mortality among hypertensive people in the community could be reduced by a rigorous stepped-care approach to the treatment of hypertension, as compared with referral ...

The occurrence of excessive amounts of antigen–antibody complexes in patients with systemic lupus erythematosus may be a consequence of over-production of autoantibodies (perhaps secondary to polyclonal B-cell activation^{1 , 2} or altered suppressor T-cell ...

The increase in the number and complexity of diagnostic and therapeutic modalities and in the total costs of health care in the United States has increased the need for reliable estimates of future requirements for medical manpower, services, and ...

Renin production and secretion by neoplastic tissue was first documented by Robertson et al. in 1967.¹ Since then, reports have appeared of more than a dozen additional cases of renin-secreting benign hemangiopericytomas of the renal juxtaglomerular ...

A quarter of a century has passed since Brock's original report¹ of the condition characterized by asymmetric septal hypertrophy and a subaortic pressure gradient (muscular subaortic stenosis).² The pressure gradient may be affected by changes in ...

Presentation of Case

A nine-year-old girl was admitted to the hospital because of proteinuria.

The child was found abandoned in Korea at about the age of three weeks and was cared for in an orphanage. At the age of six months she was adopted by an ...

In this issue of the Journal, Pollick's report¹ focuses on the ability of disopyramide to reduce or eliminate the echocardiographic and hemodynamic signs of left ventricular "outflow obstruction" in a small number of patients with muscular subaortic ...

For the past 20 years, the Centers for Disease Control (CDC) of the U.S. Public Health Service in Atlanta has been publishing the Morbidity and Mortality Weekly Report (MMWR) and mailing it free to anyone in the world who requested it.

The MMWR is a ...

Is fibrocystic disease really a distinct entity? Is it a diagnosis that can be made clinically or histologically? Does this designation imply an increased risk of breast cancer? Should we attempt to treat it? Davis et al.¹ examined these questions in 1964 ...

No extract is available for articles shorter than 400 words.

Accidental injuries are the leading cause of childhood mortality and disability.¹ Both the Surgeon General's Report on Health Promotion and Disease Prevention¹ and the Massachusetts Department of Public Health's report, "A Program for Prevention in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The article by Guyer et al. (May 20 issue)¹ draws attention to the important role that the rate of low birth weight has in the neonatal mortality rate. The birth-weight-specific rates in Sweden have previously been compared with those in ...

To the Editor: In the April 22 issue Stagno and associates reported on the implications to the fetus of primary versus recurrent maternal cytomegalovirus infection.¹ From prospective and retrospective data, the authors found that symptoms were present in ...

To the Editor: In contrast to their initial report, which emphasized either transient post-partum hypothyroidism^{1 , 2} or transient recurrence of hyperthyroidism after delivery in Graves' disease,³ the more recent report of Amino et al. (April 8 issue)⁴ ...

To the Editor: In the November 12 issue Lowrie et al. demonstrated that among patients receiving long-term hemodialysis who were placed on a diet with unrestricted protein, a higher level of blood urea nitrogen (BUN) (mid-week predialysis level, 120±10 ...

No extract is available for articles shorter than 400 words.

To the Editor: In his editorial in the March 11 issue of the Journal,¹

Solomon states that measurement of the daily excretion of Bence Jones proteins can be used as an "objective index" of a patient's response to chemotherapy. In order to interpret a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

IT began when I was about 14. Although regrettably I remember very little of my childhood and early adolescence, my first two episodes of migraine are as vivid as if they happened yesterday. My friend and neighbor, Alvin K—, and I were traveling home to ...

An inevitable question arising out of a story of achievement is, What makes this life so effective, permitting its owner to reach so far above the ranks of his fellows?

Dr. Samuel Proger, still (at 76) chairman of the board of the New England Medical ...

No extract is available for articles shorter than 400 words.

Recent interest in the mental health of the doctor has focused on "burnout" and "the impaired physician." Although the labels may be new, the concerns are not. As early as 1869, Sir James Paget had reported on the careers of 1000 former pupils and found a ...

Thirty years of experience treating suicidal persons have more than qualified Hendin to write this timely book — timely particularly because of the dramatic (250 to 300 per cent) rise in suicide rates in the United States among the 15 to 24-year age group,...

Just as law and social policy lag, struggling, behind the stunning advances of medical science and techniques, so have practical textbooks and treatises on the societal implications of such developments been slow to appear. Fortunately, the first of these ...

Is the pen mightier than the sword? Is literature mightier than medicine? Such questions suggest a contrast between two value systems and are not easily answered, but they are often pondered by intellectuals who seek to understand the relationship between ...

No extract is available for articles shorter than 400 words.

The receipt of these books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of new ...

JOSEPH GARLAND LECTURE

Dr. James M. Tanner will deliver the Seventh Joseph Garland Lecture at the Francis A. Countway Library of Medicine in Boston on October 20 at 5 p.m. The topic is "Microcosmographia Auxologica: The Study of Children's Growth as ...