A MULTICENTER randomized clinical trial, the Enquêete de Prévention Secondaire de l'Infarctus du Myocarde, compared aspirin and oral anticoagulants in men and women who had had a documented myocardial infarction. A firm conclusion about whether aspirin is ...

AN accumulation of aluminum in the bones of patients with chronic renal failure was demonstrated over a decade ago.¹ This finding was largely ignored by those studying renal osteodystrophy, since a study in animals had suggested that aluminum itself had ...

DYSMENORRHEA syndrome is a complex of symptoms characterized by lower-abdominal cramping often accompanied by backache, headache, nausea, vomiting, diarrhea, weakness, dizziness, and other systemic manifestations.^{1 , 2} In primary dysmenorrhea, menstrual ...

ONCE poststreptococcal acute glomerulonephritis is clinically healed and the urine is normal, the prognosis for these patients has been thought to be good, although occasionally an adult with progressive renal failure may recall having had "nephritis" as ...

IN the past two years there has been an unprecedented outbreak of Kaposi's sarcoma, Pneumocystis carinii pneumonia, and other opportunistic infections in male homosexuals and, to a lesser extent, in drug addicts in the United States.^{1 , 2} These cases have ...

PRIMARY myocardial disease that develops during the course of pregnancy is a rare but exacting diagnostic problem. The variation in the time of onset of this disease from the second trimester of pregnancy until well into the puerperium has led to debate ...

Presentation of Case

A three-month-old girl was admitted to the hospital because of a question of optic atrophy.

The child was born of a full-term second gestation in a mother 21 years of age. The pregnancy was complicated only by an afebrile upper-...

One of the more remarkable features of the resurgent public concern about nuclear war is the prominent role of the medical profession.

Twenty years ago, at the time of the Cuban Missile Crisis, physicians were also in the vanguard of the anti-nuclear-war ...

Dysmenorrhea and premenstrual tension are afflictions that occasionally receive renewed interest as a result of changes in both scientific and social understanding. The clinical introduction of a rapidly growing number of prostaglandin synthetase ...

The interface between medicine and nursing has become a frequent topic of debate and has captured broad public interest.¹ The recent debate has focused on nurses' increasing dissatisfaction with hospital practice, including their relationships with ...

To the Editor: It is noteworthy that the Department of Defense, while denying that the civilian-military hospital contingency system (CMCHS) is designed for nuclear war, has not offered an alternative plan for such a war — this despite the facts that ...

To the Editor: The excellent review by Rubin (November 26, 1981) and the subsequent correspondence (April 1 issue) on the use of beta-blockers in pregnancy,^{1 , 2} raise important issues. Rubin cites the study completed at the National Women's Hospital, ...

No extract is available for articles shorter than 400 words.

To the Editor: Baker et al. (April 22 issue) set out to compare two approaches to nutritional assessment.* Their experimental design, however, did not permit a comparison, because the investigators did not incorporate any final determinant of nutritional ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Bravo and his colleagues reported a simple diagnostic test using clonidine to detect pheochromocytoma (issue of September 10, 1981).¹ The test was well tolerated by all their patients. We have recently observed serious complications in two ...

To the Editor: Lankford et al. showed (November 19 issue) that an abnormal early phase of the ACTH feedback response to cortisol infusion persisted after removal of the pituitary tumor in patients who had adrenalectomy for Cushing's disease.¹ ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This is a familiar mini-encyclopedia of general orthopedics. The preface to this edition (now coauthored by Solomon) includes a proclamation that the book is "designed to be used: by postgraduates (and their teachers), by undergraduates (who may ignore ...

No extract is available for articles shorter than 400 words.

Both these short textbooks address the stabilization of fractures. Concepts in External Fixation attempts to present a comprehensive survey of the external fixation of fractures for both the engineer and the surgeon. The book is intended to be useful for ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

With clinical relevance and in smoothly flowing language, the authors have filled a need and fulfilled their purpose of presenting a "critical summary of current knowledge about the behavioral consequences of... head injury...." One senses an underlying ...

The objective of this book, according to the Preface, is to provide information for the management of medical problems in surgical patients. Most of the 17 chapters are organized by specialty and focus on one medical field after another, such as allergy, ...

Colonoscopy is a textbook of colonic endoscopy written by the most accomplished endoscopist to report his experience with this revolutionary clinical tool. The most useful aspect of the book is its presentation in a concise and easily retrievable form of ...

RESEARCH IN HUMAN SUBJECTS

A conference entitled "Research in Human Subjects with Special Problems" will be held at Suffolk University Law School in Boston on October 10 and 11.

Contact Joan Rachlin, Public Responsibility in Medicine and Research, 15 ...

THE ethics of medical experimentation on human subjects has attracted much attention in recent years. There has, however, been rather less attention paid to the special ethical problems and dilemmas posed by the randomized clinical trial.

The sheer number ...

I greatly appreciate and am honored by your invitation to give the Shattuck Lecture this year. The generosity and public-spiritedness of Dr. George Cheyne Shattuck, the benefactor of these lectures, and the distinguished speakers who have kept this ...