SIX to 12 hours after the early response to an antigen-inhalation challenge, many patients with asthma have a further, often more severe increase in airways obstruction (the late reaction).¹ It has been suggested that the late reaction may have more ...

IN infants with a large ventricular septal defect, the signs of a large left-to-right shunt and excessive pulmonary blood flow are often not apparent in the period immediately after birth.¹ Clinical manifestations usually become evident several weeks ...

A HEMODYNAMICALLY important shunt through a patent ductus arteriosus is a major problem among premature infants.^{1 , 2} A large left-to-right shunt through a patent ductus arteriosus has been associated with increased incidences of bronchopulmonary ...

CONTINUING medical education is a major industry in Canada and the United States. Miller estimates that $500 million is spent on it annually by United States physicians, medical schools, hospitals, medical societies, industry, and governments.¹ An ...

ATAXIA-telangiectasia is a genetically linked multisystem degenerative disease with abnormalities in both humoral and cellular immune responses. IgA deficiency is common in this disorder¹; IgE deficiency occurs,² as does low IgG.^{3 , 4} We previously found ...

HUMAN B-cell malignant tumors result from the proliferation of single clones of cells that express surface markers characteristic of normal B lymphocytes.^{1 , 2} In particular, the surface immunoglobulin expressed by these cells is monoclonal — i.e., ...

IN the past, each hormonal peptide was traditionally considered a unique product of a single cell type that was localized in distribution to a limited region of the body known as an endocrine gland (Table 1). These boundaries were too limited. For some ...

Presentation of Case

First admission. A 68-year-old woman was admitted to the hospital because of anemia and fever.

She was well until 3 1/2 weeks earlier, when malaise occurred, accompanied by a rise of the temperature to 38.3°C daily. One week later ...

The influence of severe chronic anemia on cardiovascular dynamics has long been recognized. The decreased blood viscosity and vascular tone that accompany the reduced oxygen-carrying capacity lead to increased venous return and preload, with increased ...

Doctors learn. Moderate hypertension is being treated much more vigorously now than a decade ago. The CT scan has replaced a variety of poorer imaging techniques for the assessment of neurologic impairments. Early ambulation after myocardial infarction is ...

Ataxia-telangiectasia is a rare multisystem disorder that generally presents within the first three years of life and culminates in death before the age of 20. Progressive cerebellar ataxia with other neurologic problems and cutaneous venous ...

In 1963 Oudin and Michel¹ and Kunkel et al.² independently reported that antibodies of a given specificity expressed serologically defined determinants of their own that distinguished them from other antibodies. These unique antigens on immunoglobulin ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: For a clinical screening test to be delivered by any physician once a year to any woman at risk, it should be simple, brief, and efficient.

From July 1972 to January 1980, one of us performed 14,328 clinical breast examinations in the St. ...

To the Editor: Pityriasis rubra pilaris is a disease characterized by low serum levels of retinol-binding protein (RBP).¹ The defect is probably transmitted genetically in an autosomal dominant manner.² The clinical picture is characterized by an ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Knauer et al. recently demonstrated the occurrence of platelet activation during IgE-mediated acute airway reactions by an increase in plasma platelet factor 4 — an indicator of in vivo platelet activation — after antigen challenge in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In these two massive volumes, Ronald D. Miller, assisted by 31 coauthors, has partially met the need for a comprehensive American reference work that covers the whole field of anesthesia. Although our British colleagues have written several outstanding ...

This latest edition of a well-known and respected book is welcomed by the surgical pathologist. Seven years have passed since the previous publication of Surgical Pathology (coauthored by Ackerman and Rosai). The present edition appropriately honors the ...

Books on vascular surgery continue to proliferate like rabbits or gerbils, and they come in many shapes, sizes, prices, and levels of quality. One of the best of the more concise books is the third edition of Peripheral Arterial Disease, largely by Dr. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The term "Western diseases," as used by the editors of this book, is a polite euphemism for what are sometimes known as "diseases of civilization," "diseases of development," or "diseases of affluence." As one editor says,"... it proved obnoxious to teach ...

Despite its title, this is an interesting book. Its "lively heroes" (as they are called in the introduction) seem to leap right out of the pages of contemporary novels by Dickens and Trollope. The authors, in their conclusion, stress their heroes' vanity ...

COURSES AT THE UNIVERSITY OF KENTUCKY

The University of Kentucky College of Medicine will offer six postgraduate courses in the coming months: the "Advanced Cardiac Life Support Provider/Instructor Course" (March 5–7); "Medical Aspects of Sports Symposium:...

No extract is available for articles shorter than 400 words.