PERCUTANEOUS transluminal coronary angioplasty improves the angiographic appearance of coronary-artery stenoses and leads to symptomatic improvement.¹ Although the improvement may be caused by an augmented capacity of the dilated coronary artery to ...

SODIUM fluoride is a potent stimulator of bone formation; its net effect in patients with osteoporosis is a substantial increase in the bone mass of the axial skeleton.^{1 2 3 4} Concurrent administration of supplementary calcium with or without vitamin D, ...

CYTOTOXIC drugs such as cyclophosphamide^{1 2 3 4 5 6} and chlorambucil^{7 8 9} have been shown to induce longer remissions of minimal-change nephrotic syndrome than do glucocorticosteroids. However, the potential side effects of these drugs restrict their use ...

IMMUNE responses are similar to other complex biologic processes, such as blood clotting and complement activation, in that they are modulated by a series of positive and negative regulatory factors. Normal immunologic homeostasis requires an appropriate ...

EACH day physicians encounter stresses that are an intrinsic part of medical practice. Those who are vulnerable may become unable to practice medicine without the intrusion of seriously neurotic or inappropriate behavior: that is, they become impaired ...

TAKAYASU'S arteritis (aortic-arch syndrome) is a rare inflammatory disease that involves large arteries and often leads to segmental-vessel necrosis and subsequent occlusive or aneurysmal sequelae.¹ The disease has a worldwide distribution, and its cause ...

SINCE 1977 there have been numerous outbreaks of nosocomial Legionnaires' disease; however, in only one was a reservoir established for Legionella pneumophila. Dondero and his colleagues have suggested that the organisms were spread from a contaminated ...

Presentation of Case

A 63-year-old man was admitted to the hospital with pain in the legs.

He was well until six months earlier, when he began to have dyspnea that caused him to discontinue jogging 5 miles (8 km) daily. The dyspnea progressed until it was ...

One of the remarkable paradoxes in contemporary American medicine is the presence of a vague but definite malaise surrounding radiologic diagnosis at a time of unparalleled excitement and accomplishment in the development of imaging hardware and ...

Panic after a diagnosis of cutaneous malignant melanoma commonly arises from fears of early death and disfiguring surgery. Yet, in the United States today, most cutaneous melanomas are diagnosed while they are in an early and curable stage, before ...

No extract is available for articles shorter than 400 words.

To the Editor: Agranulocytosis is one of the most commonly reported adverse reactions to drugs, second only to skin rashes. Idiosyncratic agranulocytosis may or may not be dose dependent; it is unpredictable and usually reversible upon discontinuation of ...

No extract is available for articles shorter than 400 words.

To the Editor: We have recently observed a patient in whom chest pain and ST-segment elevation paradoxically developed after the administration of nitroglycerin. The patient was a 53-year-old woman with Class II angina pectoris who had a single stenosis ...

To the Editor: We were interested to read the report by Fisher et al.¹ in the July 2 issue, confirming that higher estrogen-receptor levels in breast carcinoma were associated with a greater probability of disease-free survival. In our study,² patients ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This book by a well-known and beloved clinical scientist is a delight to read and should appeal to a number of audiences. Its primary purpose is to document the history of clinical research in the United States. The formative years between 1905 and 1945 ...

No extract is available for articles shorter than 400 words.

I cringed when I saw the word "superdoctors" in the last sentence of the introduction to this book. Surely such a media-hype term is out of place in a book intended for a scientific audience. The recurrence of that particular epithet throughout the book, ...

The history of medicine is replete with accounts of those who have endeavored to heal the sick and have only sometimes succeeded. However fascinating the chronicles of affliction may be, lists of names and dates contribute little to any real ...

Parasitic infections continue to ravage one third of the world's population. Many immunologic techniques have been developed to foster a greater understanding of the pathogenesis of these diseases and to stimulate the development of vaccines. Cohen and ...

PROGRAMS OF THE UNIVERSITY OF CALIFORNIA-SAN FRANCISCO SCHOOL OF MEDICINE

The School will offer four post-graduate programs in the coming months: "Current Topics in Nuclear Medicine (March 13 and 14); "Diagnostic Radiology" (March 15–19); "B-Scan ...

Funding the End-Stage Renal-Disease Program

The Reagan administration, in a climate in which federal budget cutting is the overriding priority, is moving to implement policy changes in the End-Stage Renal-Disease (ESRD) Program that were approved by ...