Since the first report of Harvey et al.,¹ numerous investigators have maintained that alveolar hypoxia and arterial hypoxemia cause right heart failure through a vasoconstrictive effect on pulmonary arteries and arterioles, and a direct cardiodepressant ...

Trimethoprim (TMP) and sulfamethoxazole (SMX) both interfere with bacterial folic acid synthesis by inhibiting sequential enzymes in the folate metabolic pathway: dihydrofolate reductase and dihydropteroate synthetase, respectively.^{1 , 2} Among bacterial ...

Liver dysfunction is a common problem among patients with chronic renal failure. Infection with hepatitis B virus or cytomegalovirus and the use of agents such as drugs and alcohol are some of the many recognized causes of the acute episodes of liver ...

IN the fall of 1980, the United States Food and Drug Administration advised pregnant women to avoid caffeine-containing foods and drugs or to use them sparingly.¹ Caffeine is a methylxanthine close in structure to the purines that build genetic material. ...

The modern era of neuroendocrinology was ushered in just over a decade ago with the isolation and characterization, from ovine¹ and porcine² hypothalamic tissue, of a tripeptide (pyroglutamyl-histidyl-proline amide), which was designated thyrotropin-...

Polyneuropathy is a recognized complication of poisoning by some organophosphate plasticizers and insecticides.^{1 , 2} The hazards of organophosphate pesticides for human beings have been limited by screening of candidate compounds and exclusion of those ...

Presentation of Case

A 73-year-old woman was admitted to the hospital because of dyspnea.

There was a 25-year history of mild recurrent poly-arthritis. Nineteen years before admission a test for rheumatoid factor was positive in a titer of 1:1920. ...

The effect of sleep on the pathogenesis and progression of disease has been ignored for decades. In recent years the availability of an accurate and reliable ear oximeter¹ has revolutionized our ability to study oxygenation during sleep, and we have begun ...

Hemodialysis is remarkably safe. Whether it is performed by professionals in a hospital or clinic or by the patient at home, the risk of death due to technical failure or human error in a single dialysis is only one in 76,138.¹ Over a 10-year course of ...

A survey of regulations in New York City's methadone clinics, conducted five years ago, showed why physicians lacked authority in their clinics and had little time to listen to their patients.¹ Every therapeutic decision was governed by guidelines laid ...

REPORT FROM THE COMMITTEE ON MATERNAL WELFARE

Fatal Respiratory Distress

An apparently healthy 29-year-old gravida II, para I whose first baby had died after premature birth at 25 weeks of gestation underwent cervical cerclage early in the second ...

No extract is available for articles shorter than 400 words.

To the Editor: Maternal pulmonary edema has been reported only rarely among recently summarized adverse reactions to β-agonistic drugs for the treatment of premature labor.¹ We report an additional case, associated not only with the use of the only FDA-...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In the issue of June 14, 1979, Aronoff, Daughaday, and Laws proposed that cerebrospinal-fluid rhinorrhea in a patient receiving bromocriptine therapy after incomplete resection of a prolactinoma was due to a fistula that had been occluded ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A Vermont farmer in his late 50s, an independent and suspicious man, reluctantly presented himself at my office, demanding treatment for upper-gastrointestinal-tract distress. Although his vocabulary seldom extended beyond "Yup" and "Nope,"...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Boots Pharmaceuticals, a British firm, is now launching a major program to promote a nonsteroidal anti-inflammatory agent — the Rufen brand of ibuprofen — directly to the consumer. Such a campaign is cause for concern to the medical ...

The names of various medical specialties are surprising. Some refer to districts of the body (ophthalmology and dermatology), some to techniques (roentgenology and surgery), some to age (geriatrics and pediatrics), and some to territorial imperatives (...

In Going High, Dr. Houston has succeeded in combining current knowledge of the physiologic and the clinical effects of the mountain environment and presenting it in an enlightening historical perspective. He has made a valuable contribution by explaining ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This is a single-authored textbook for advanced undergraduates or beginning graduate students in a variety of disciplines requiring an introduction to neurophysiology. To provide a framework for his discussions of this special area of medical science, ...

This book meets the growing need for an introduction to neuroscience that can serve as a textbook for course work or as a reference for the neuroscientist or practicing physician seeking knowledge about the nervous system. It is interesting that "neural ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of ...

"WHAT COMES AFTER SUCCESS?"

Dr. Gene Bocknek, Director of the Boston University Counseling Psychology Program, will offer a self-awareness seminar series for physicians entitled "What Comes after Success?" The series of eight biweekly evening meetings ...