By reducing impedance to left ventricular ejection, hydralazine can produce substantial short-term improvement in cardiac performance in patients with severe chronic heart failure.^{1 2 3 4} Although a number of reports have noted an amelioration of dyspnea ...

Chronic granulocytic leukemia (CGL) is associated with a median survival time of two to four years, with few long-term survivors and no cures.¹ It usually terminates in blast crisis — at times preceded by a brief accelerated phase — which is generally ...

Lymphomatoid granulomatosis, as originally described, is a disease characterized by infiltration of various organs with a polymorphic cellular infiltrate consisting of atypical lymphocytoid and plasmacytoid cells together with granulomatous inflammation ...

Acritical and central problem in the provision of health-care services in rural areas is the availability of trained personnel. This is especially true in view of the maldistribution of physicians.¹ Analyses suggest that a complex set of professional and ...

Nonketotic hyperglycinemia is a rare autosomal recessive inborn error of glycine metabolism, characterized by markedly elevated levels of glycine in plasma, urine, and particularly cerebrospinal fluid. The disease carries a grave prognosis, for ...

Reactive perforating collagenosis (RPC) is a skin disorder characterized by extrusion of collagen fibers through the epidermis. This rare form of cutaneous perforating disease, first described by Mehregan et al. in 1967,¹ usually begins in infancy or ...

Galactosemia is a molecular disease of genetic origin that is characterized by a deficiency of galactose-1-phosphate uridyltransferase.^{1 , 2} The resulting severe impairment of galactose metabolism has been recognized for over half a century, and the ...

Granulomatous arteritis, which occurs through cell-mediated immune mechanisms, can be seen in several disease states. This chronic process is not regarded as an inherited phenomenon. We report on a family with granulomatous arteritis, associated with ...

Presentation of Case

A 30-year-old man was admitted to the hospital because of confusion and headaches.

He was well until one month previously, when intermittent headaches developed. Two weeks before admission he began to have nausea, vomiting, and ...

Few things a doctor does are more important than relieving pain. Yet the treatment of severe pain in hospitalized patients is regularly and systematically inadequate.^{1 2 3 4 5} One study showed that 73 per cent of patients undergoing treatment for pain ...

Most physicians are aware of the "brain drain," which siphons off trained physicians from developing countries into the manpower pool of developed countries, but unfortunately, few physicians appreciate the role of undrained brains — the bright, dedicated,...

A new approach is needed for organizing and financing the delivery of long-term services, which are defined as the full spectrum of medical, rehabilitative, and maintenance/custodial services required by disabled adults and the vulnerable elderly. In ...

No extract is available for articles shorter than 400 words.

To the Editor: In six years of experience we have performed 140 procedures for diagnostic aspiration or drainage of abscesses. During that time, 63 patients were referred to us for possible drainage. We concluded that only 45 (71 per cent) were suitable ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

With this review by Dr. Vaillant, the Book Reviews section of the Journal begins a new policy of reviewing selected audio-visual materials of interest to our readers.

Alcoholism and the Physician provides an 80-minute mini-course on alcoholism in the ...

The Substance Abuse Problems provides a remarkable overview of the field of drug abuse, combining epidemiologic, historical, clinical, research, social, and political perspectives. It contains nearly 70 brief articles originally written for the Vista ...

This book arises from a symposium in which five distinguished senior psychiatrists offered their own psychoanalytic formulations of alcoholism as a disease process and discussed the implications of these respective formulations for the treatment of ...

The doctor–patient relationship has been discussed often and at length in both medical and lay writing, and it is worth wondering whether there is anything left to say. Dr. Goldwyn answers that question by showing us a somewhat different perspective ...

Writing for the public and patients is an ancient professional tradition. Today so many books are written that their sheer numbers seem certain to overload the public with too much "health information." Yet these lay medical books from physician's pens, ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of ...

CALL FOR PAPERS

Abstracts are now being accepted for the Fifth International Symposium on Brain Edema, which will be held in Groningen, The Netherlands, June 10–12. The deadline for receipt of abstracts is February 1.

Contact the Symposium Secretariat, ...

No extract is available for articles shorter than 400 words.

American industry, historically a slumbering giant when it came to influencing the delivery of health-care services that it purchased, is awakening to the need to become a more sophisticated buyer of such services for one overriding reason: Soaring costs ...