THE ultimate test of the clinical efficacy of an agent capable of limiting the size of an evolving myocardial infarction^{1 2 3} is the demonstration, in a properly controlled trial, of a reduction in mortality and complications in randomly selected patients ...

ACUTE myocardial infarction is frequently accompanied by global dysfunction of the left ventricle and continuing ischemia.^{1 2 3} In recent years recognition of the dynamic nature of this syndrome and the evidence that pharmacologic and physiologic ...

PROLONGED immobilization has long been known to result in hypercalciuria and hypercalcemia.^{1 2 3 4 5 6 7} Marked reductions in skeletal mass routinely accompany prolonged immobilization, so that "disuse osteoporosis" regularly accompanies prolonged ...

ONE of the most useful techniques in modern clinical neurophysiology is the recording of evoked potentials. An evoked potential (EP) is an electrical manifestation of the brain's response to an external stimulus. For example, the visual EP produced by the ...

THE National Cancer Institute estimates that 51,000 new cases of head and neck cancer will occur in 1982 and will result in 16,000 deaths. These cases will include 26,600 cancers of the buccal cavity and oropharynx (9150 deaths), 10,700 cancers of the ...

RED-CELL-membrane architecture has been extensively studied in recent years.^{1 , 2} When the cells are hypotonically lysed and washed free of hemoglobin, the resulting membrane ghosts consist of the lipid bilayer and associated proteins. When ghosts are ...

Presentation of Case

A 31-year-old woman was admitted to the hospital because of the abrupt development of proteinuria and edema.

There was a history of chronic anemia and recurrent oral ulceration since childhood. Eleven years before entry, after the ...

This issue of the Journal includes reports of two clinical trials in patients with acute myocardial infarction,^{1 , 2} testing the hypothesis that nitroprusside, a vasodilator, will reduce mortality when given during the initial 24 to 48 hours of ...

Knowledge of the structure and function of the red-cell membrane has increased during the past several years. The advent of highly sensitive methods for protein preparation and purification has enabled us to identify structural membrane components that ...

There is frequently a cyclical pattern to the reception given to new drugs: At first, exciting preliminary observations lead to exaggerated claims of efficacy and safety. Secondly, controlled trials find the therapy either to be less effective than ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Reichman et al. believe that formula feeding itself leads to excessive fat deposition in preterm infants (December 17 issue).¹ In the light of the data in their article and elsewhere² we believe that they are mistaken.

These authors gave ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In their article in the December 10 issue, Gorden and his colleagues¹ once more provide data on patients with various types of tumors associated with hypoglycemia. The authors report that 19 of 52 patients with hypoglycemia associated with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Our committee of physicians and scientists who are involved in glutamate research, read with incredulity the letter by Allen and Baker on Chinese-restaurant asthma (November 5 issue).¹

The authors reported the content of several papers ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We wish to bring complementary information from overseas with respect to the recent article by Fishbane and Starfield¹ and the correspondence in the December 17, 1981, issue² about data from a national sample of visits by general ...

To the Editor: In their Sounding Board article in the December 17 issue, Allegrante and Green¹ criticize the administration's policy regarding the promotion of the concept of individual responsibility for disease prevention versus provision of health ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This interesting book describes life (and sometimes death) in a modern neonatal intensive-care unit and documents the striking advances made in recent years in the care of our tiniest citizens. The author is a medical writer for Newsday, who has won an ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Basic Science

Finite Elements in Biomechanics. Edited by R. H. Gallagher, B. R. Simon, P. C. Johnson, and J. F. Gross. 404 pp., illustrated. New York, John Wiley, 1982. $49.95.

Hemodilution and Flow Improvement. (Bibliotheca Haematologica. No. 47.) Edited ...

DISEASES OF THE LIVER

A course entitled "Diseases of the Liver: Update on Practical Diagnosis and Management" will be held at the University of Chicago on June 26. The fee is $140.

Contact Elsie M. Newton, 1307 E. 60th St., Chicago, IL 60637; or call (312)...