PULMONARY vascular disease is a discouraging illness in its terminal stage, whether the disorder is idiopathic or due to congenital heart disease (Eisenmenger's syndrome); vasodilators are unsuccessful, and care is only supportive. It has been appreciated ...

THE presence of Bence Jones proteinuria is usually indicative of a neoplastic process such as multiple myeloma, amyloidosis, or Waldenström's macroglobulinemia. It has been stated that Bence Jones proteinuria with excretion of more than 1.0 mg per ...

WITH the declining frequency of Rh isoimmunization, nonimmune fetal hydrops is becoming the predominant form of hydrops encountered in the Western countries.¹ Nonimmune hydrops may be related to chronic intrauterine anemia, intrauterine hypoproteinemia ...

SEVERE hemophilia is devastating if treated timidly, for repeated hemorrhages eventuate in crippling joint, muscle, and nerve damage.^{1 2 3} Frequent spontaneous hemorrhages preclude regular school attendance by the child and uninterrupted work by the adult,...

THE more frequent recognition of endocrine tumors of the pancreas within the past decade can be largely attributed to better characterization of the associated clinical syndromes, coupled with improved methods of diagnosis. The single most important ...

ALTHOUGH many fetal anatomic abnormalities can now be diagnosed by sonography, only a few will affect prenatal management.¹ In the fetus with severe bilateral hydronephrosis secondary to urethral obstruction, the urinary tract should be decompressed as ...

MOST investigators would agree that both heredity and environment are important determinants in the development of essential hypertension. Among the environmental factors, dietary sodium has a prominent but incompletely defined role. Familial aggregation ...

Presentation of Case

A 19-month-old boy was admitted to the hospital because of atelectasis of the left lung.

The child was born of a full-term pregnancy, which was not associated with the ingestion of medications or alcohol, although his mother smoked ...

Of all the illicit drugs available in this country, marijuana is by far the most widely used and the most controversial.

During the late '60s and early 70s, "pot" was the symbol of the drug counterculture, but its use has increased so much recently, ...

Over a century elapsed between Henry Bence Jones' discovery of a urinary protein with unusual thermal properties in patients with multiple myeloma¹ and Edelman and Gally's demonstration² that this curious protein was the light polypeptide portion (kappa ...

Patients with genetic diseases have long presented a therapeutic and financial challenge to the health-care system.¹ With the advent of cryoprecipitates of plasma that contain concentrated factor VIII, physicians caring for patients with hemophilia began ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Brodsky et al. recently described a patient treated with verapamil for angina pectoris, in whom hepatotoxicity developed.* We have encountered a similar problem in one of our patients.

A 48-year-old man entered a clinical-efficacy trial of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

These are two useful books — but not for every reader. How does one review a handbook that consists of 33 chapters containing approximately 900 double-column pages and is divided into two major sections — "Human Resources Management" and "Labor Relations" ...

When Oliver Goldsmith wrote in The Good-Natur'd Man that "Silence gives consent," he was obviously not contemplating modern-day medical practice. This is proved beyond any reasonable doubt by the daily anguish, complication, and confusion caused by the ...

Concepts of Health and Disease is a welcome expansion of debates surrounding attitudes toward health. Its particular value lies in abandoning any single point of view in order to present the thinking of 55 authors whose careers span three centuries and a ...

Robbins and Dyer state in their preface that over the past decade ethical issues in medicine have been studied and discussed as never before, as have such related items as accountability and "unprecedented attention to individual rights." Then they warn ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Basic Science

Atlas of Molecular Structures in Biology. Vol. 2. Haemoglobin and Myoglobin. By G. Fermi and M. F. Perutz. 104 pp., illustrated. New York, Oxford University Press, 1981. $45.

Basic Mechanisms of Cellular Secretion. (Methods in Cell Biology. ...

"NEUROLOGY FOR REHABILITATION PERSONNEL"

A symposium entitled "Neurology for Rehabilitation Personnel" will be held at the 57 Restaurant in Boston on March 26 and 27. The fee is $120.

Contact Mrs. Ruth M. Glotzer, Office of Continuing Education, 136 ...

This two-part report was submitted to the Congressional Office of Technology Assessment as part of a study entitled "Strategies for Medical Technology Assessment." In Part I we examine the effects of coverage and reimbursement on biomedical innovation. We ...