THERE is increasing evidence that hemorrheologic factors may be involved in the pathogenesis of a number of thrombotic diseases.^{1 , 2} Diabetes mellitus is associated with a high prevalence of microvascular and atherosclerotic disease, and abnormalities of ...

PROTHROMBIN is a vitamin K-dependent blood-coagulation protein that is synthesized in the liver. The NH₂-terminal domain contains 10 γ-carboxyglutamic acid residues^{1 2 3} and confers the metal-binding properties unique to this class of calcium-binding ...

FOR many years methylxanthines, particularly aminophylline, have had an important role in the management of airway obstruction. These drugs have usually been used because of their stimulatory effect on the central nervous system and their relaxant effect ...

IN LATE 1980, the Professional Standards Review Organization (PSRO) program was simultaneously marked for extinction by both the outgoing and incoming administrations — for opposite reasons. While transition Republicans were publicly promising to ...

IN 1682 the English physician Thomas Sydenham captured the essence of borderline personality in a single phrase. "All is caprice," he wrote, "they love without measure those whom they will soon hate without reason." ¹ Three centuries later, this remains ...

HYPONATREMIA occurs frequently in patients with congestive heart failure who have moderate fluid intakes (1 to 3 liters per day).¹ It is not clear whether persistent release of arginine vasopressin (AVP — the mammalian antidiuretic hormone [ADH]) or ...

THE difficulties in consistently prolonging survival after orthotopic liver transplantation have been documented by us¹ and by Calne.² In this report we describe a new trial of orthotopic liver transplantation in 14 patients who were scheduled to be ...

Presentation of Case

A 76-year-old woman was admitted to the hospital because of a neurologic disorder.

She was well until two years earlier, when a tender nodule developed on the nasal bridge and gradually increased in size. Examination showed a firm ...

IN this issue of the Journal, Aubier and his colleagues¹ report that aminophylline in the usual therapeutic dose enhances the contractile force of the normal human diaphragm by 15 per cent and promptly reverses fatigue induced by inspiratory resistive ...

Saints Cosmas and Damian, twin brothers and converts to Christianity, dedicated their lives to the healing of the sick during the era of Diocletian. Cosmas was a physician, Damian a surgeon. Most well known among the deeds attributed posthumously to these ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

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To the Editor: We are surprised that Dr. Folkman, in his discussion of the investigation of the child in the Case Record of the December 18 issue,¹ did not question her clinician's use of aortography, particularly when its results did not appear to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A consistent finding in patients with Bartter's syndrome is a reduction in the ex vivo responsiveness of their platelets to such aggregating agents as adenosine diphosphate (ADP), epinephrine, thrombin, and collagen.^{1 2 3} This platelet ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Münchausen's syndrome is a psychopathologic condition distinct from other forms of factitious disease and malingering.¹ Characteristically, patients with this syndrome travel widely from hospital to hospital, presenting with illnesses that ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

PHYSICAL & OCCUPATIONAL THERAPY IN PEDIATRICS

A new quarterly journal, Physical & Occupational Therapy in Pediatrics, is now being published. It is primarily geared to "provide the practicing pediatric physical or occupational therapist with information ...

The Reagan administration, remarkably successful in its efforts to cut the fiscal 1982 federal health budget, is now moving to design a "pro-competition" health proposal. Although the process has barely begun, the prime goals of the exercise seem clear: ...