THE differential diagnosis of polyuria presents one of the classic problems of clinical medicine. In the absence of glucosuria, it is necessary to distinguish among three causes of increased urine excretion: deficient release of the antidiuretic hormone ...

PUBERTY is initiated by the pulsed nocturnal secretion of gonadotropins. These gonadotropin pulses, resulting from the episodic release of luteinizing hormone-releasing hormone (LHRH) by the hypothalamus, stimulate gonadal sex-steroid secretion, which ...

STUDIES of atopic allergy ("allergy") have provided new insight in defining the epidemiologic and genetic basis for the human immune response.^{1 , 2} Allergy is characterized by the development of antibody responses of a unique immunoglobulin — IgE³ — after ...

Drugs Acting on Adrenoreceptors

Isoxsuprine

Pharmacology

Isoxsuprine is a phenylethylamine derivative of epinephrine. The compound is said to be an alpha-adrenoreceptor antagonist with beta-adrenoreceptor-stimulating properties, but the vasodilator ...

SHOULD patients be given direct information on the risks and benefits of prescription drugs in order to help them formulate an effective informed consent? An effort to move toward a system of patients' "package inserts" for all prescription drugs has been ...

IN patients free of pulmonary venous occlusive disease or mitral-valve obstructive disease or both, the pulmonary artery wedge pressure reflects the left atrial pressure and thus the left ventricular filling pressure. Care of a critically ill patient with ...

METRONIDAZOLE has been widely used for prophylaxis and therapy of anaerobic infections in abdominal and gynecologic surgery.^{1 2 3 4} Although clinical trials have demonstrated the efficacy of suppository formulations of metronidazole,^{5 6 7 8} there have ...

CARTIER and Hamet¹ described a patient with calculi formed by 2,8-dihydroxyadenine in 1974. Such calculi are positive for uric acid with standard wet chemistry tests.² The poorly soluble purine 2,8-dihydroxyadenine is excreted in the urine because of a ...

Presentation of Case

A 51-year-old man was admitted to the hospital because of a question of a nasal tumor.

He was well until three years earlier, when progressive bilateral nasal obstruction developed. Two years before admission he entered another ...

The differential diagnosis of nonglucosuric polyuria (i.e., of diabetes insipidus) presents us with an ironic twist. In many ways, it is a prototype of the application of basic scientific principles to the diagnosis of disease. In the form of the Hickey–...

One of the many new insights afforded by the advent of radioimmunoassays has been the recognition that the pattern of adenohypophyseal hormone secretion is episodic rather than continuous, as had been previously supposed. This pattern is particularly ...

Marie! Marie! Oh let me repeat that name a hundred times, a thousand times over; for three days now it has lived within me, oppressed me, set me afire. . . . Heaven, Hell, everything, all is within you, redoubled. . . . Oh! Leave me free to rave in my ...

Bennett — Theodore Bennett, M.D., formerly of Brookline, died on October 22. He was in his 77th year.

Dr. Bennett received his degree from Tufts College Medical School in 1928. He was a member of the American Medical Association, the American Academy of ...

To the Editor: In response to the letter of Hymowitz in the October 1 issue,¹ we would like to report a case of toxic-shock syndrome associated with use of a diaphragm.

A 23-year-old woman presented to the emergency room with an eight-hour history of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Dr. Murray F. Brennan has written an interesting, accurate, but somewhat ambivalent article on total parenteral nutrition (TPN) for the patient with cancer (August 13 issue).1 He opens with a discussion of the cost of the technique to the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The preface of Sleep Disorders: Insomnia and narcolepsy states that the work is intended to "fill the need for a comprehensive reference book on insomnia and narcolepsy." Unfortunately, it is not comprehensive, and the suggestion that it will be is ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In her book addressed to women entering or passing through menopause, Ms. Gray strikes the right tone. She is reassuring, comforting, and informative about this complex experience — potentially the most trying experience a healthy woman undergoes in life. ...

Medicine

Neurology

The Cranial Nerves: Anatomy, pathology, pathophysiology, diagnosis, treatment. Edited by M. Samii and P. J. Jannetta. 664 pp., illustrated. New York, Springer-Verlag, 1981. $106.

Disorders of the Cerebellum. (Contemporary Neurology ...

SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL, BOSTON

Two seminars will be held on the following Tuesdays at 4:30 p.m. On January 5, "Gene Transfer and Gene Expression"; and on January 19, "The Medical Implications of Nuclear Weapons and Nuclear War."

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