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December 17, 1981  Vol. 305 No. 25

Original Articles
1483-1489

    IT is still uncertain whether physical activity can favorably influence the natural history of coronary atherosclerotic heart disease in human beings.1 Although most of the more recent studies appear to support the hypothesis that regular aerobic exercise ...

    1489-1495

    Abnormalities in the electrolyte and water content of luminal liquid or "secretions" of the airways, sweat glands, intestinal and reproductive tracts, and pancreas suggest that cystic fibrosis is characterized by a generalized epithelial dysfunction.1 , 2 ...

    1495-1500

    The Committee on Nutrition of the American Academy of Pediatrics suggests that the "optimal diet for the low-birth-weight infant may be defined as one that supports a rate of growth approximating that of the third trimester of intrauterine life." 1 This ...

    Special Article
    1501-1507

    CONTROVERSY over the desirability of cost sharing in health-insurance policies has simmered for decades and has occasionally boiled over, in part because of the meager quantitative evidence about the effects of cost sharing on the demand for services and ...

    Medical Intelligence
    1508-1513

    MANY drugs described as cerebral vasodilators have been in use for over 20 years. Most were originally developed as peripheral vasodilators and were then used to improve cerebral blood flow in patients with cerebrovascular disease or dementia. These ...

    1513-1517

    FOLATE deficiency, a common occurrence in patients with inflammatory bowel disease,1 , 2 has been ascribed in part to the therapeutic use of sulfasalazine.1 In vitro, this drug is an inhibitor of the intestinal transport of folic acid (...

    1517-1518

    SIMIAN virus 40 (SV40) is a papovavirus that is latent in rhesus-monkey kidneys used for tissue culture of poliovirus. SV40 was present in vaccines administered to millions of people and was later found to be oncogenic in laboratory animals, notably ...

    Case Records of the Massachusetts General Hospital
    1519-1524

    Presentation of Case

    A 55-year-old man was admitted to the hospital because of intermittent claudication of the arms.

    He was well until five years earlier, when a diagnosis of diabetes mellitus was made. Dieting resulted in a weight reduction from 90 to ...

    Editorials
    1525-1526

    Despite a 22 per cent reduction in mortality from coronary atherosclerotic heart disease in men (and a 27 per cent reduction in women) in the United States from 1969 to 1977,1 this disease remains the 20th-century epidemic for the Western world and the ...

    1526-1528

    In 1970, personal health expenditures in the United States totaled $65 billion. In 1980, this figure had risen to $218 billion.1 It is therefore not surprising that discussions about existing health-insurance coverage and possible alternative ways of ...

    Sounding Board
    1528-1529

      The rhetoric of the new administration's national health policy reflects a shift in priorities that could have a profound impact on the lives and health of Americans by the end of the decade. It is a move away from what has been a heavy economic ...

      Correspondence
      1529-1530

      To the Editor: The article by Modlin and his colleagues in the August 13 issue regarding perinatal echovirus 11 infection brought a wisp of déjà vu. The letter quoted below was submitted to the Journal in 1979 as a demonstration of in utero echovirus 11 ...

      1530

      No extract is available for articles shorter than 400 words.

      1530-1531

      No extract is available for articles shorter than 400 words.

      1531-1532

      To the Editor: Contamination of home or office air conditioners with thermophilic actinomycetes has been reported to cause hypersensitivity pneumonitis.1 We report here a case of hypersensitivity pneumonitis related to a car air conditioner.

      A 40-year-...

      1532-1534

      No extract is available for articles shorter than 400 words.

      1534

      No extract is available for articles shorter than 400 words.

      Book Reviews
      1534-1535

      These three books take up different forms of that now-pervasive phenomenon that many physicians consider a serious distraction, if not a serious threat to the practice of medicine: planned change.

      Altman and his colleagues present an edited version of ...

      1535

      This book is a report of the findings of a major comparative study of health-manpower policies and practices, funded by the United States Bureau of Health Manpower. The purpose of the study was "to gain insights for health policy in the United States." ...

      1535-1536

      The editors have compiled a collection of lively, informative, and occasionally provocative articles, largely drawn from recent issues of Health Care Management Review. They focus on the importance and use of strategic planning in health organizations — ...

      1536

      As the subtitle states, this small work is a second study of patients and their general practitioners in the National Health Service (NHS). When Ann Cartwright's first study, Patients and Their Doctors, was undertaken in 1964, the future of general ...

      1536-1537

      Rural Medicine is the fourth in a series of studies sponsored by the University Health Policy Consortium, formed in 1977 by Boston University, Brandeis University, and the Massachusetts Institute of Technology. This study should be of interest to health-...

      Books Received
      1537

      Alcoholism and Drug Abuse

      Alcohol and Public Policy: Beyond the shadow of prohibition. Edited by Mark H. Moore and Dean R. Gerstein. 463 pp. Washington, D.C., National Academy Press, 1981. $15.

      Drug Dependence and Alcoholism. Vol. 1, Biomedical Issues, ...

      Notices
      1537-1538

      ALLERGY, IMMUNOLOGY AND PULMONOLOGY

      The "Keystone Summit on Allergy, Immunology and Pulmonology" will be held in Keystone, Colo., January 17–22. The fee is $225.

      Contact Mary Fletcher, National Jewish Hospital/National Asthma Ctr., 3800 E. Colfax Ave., ...

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