THE term "depressive disorders" (or "affective disorders") denotes a prevalent (1 to 2 per cent) major illness characterized by episodes of dysphoria associated with somatic symptoms. It may have a manic-depressive (bipolar) or purely depressive (unipolar)...

THE level of serum IgG in the full-term infant is equal to that in the mother or higher, reflecting active transport across the placenta. The level of transplacentally acquired IgG falls rapidly within the first three to four months of postnatal life. ...

THE apparently special role of the thymus in myasthenia gravis is of particular interest because of the autoimmune nature of the disorder and the evidence that developing T cells acquire tolerance to self antigens in the thymus.^{1 , 2} The evidence ...

HISTORICALLY, health-manpower planning has suffered from both inadequate methodologic approaches and lack of relevant data.¹ Consequently, planning has drawn heavily on professional opinion in defining problems, analyzing data, and making policy ...

DRUGS that competitively antagonize the effects of catecholamines at beta-adrenoreceptors have been in clinical use since the mid-1960s. Although they were initially used for the prevention of angina, these agents subsequently found wide clinical ...

THE glomerular lesion of autologous immunecomplex nephritis in rats (Heymann nephritis) is analogous to that of membranous glomerulopathy in human beings.¹ One of the components of the immune aggregates deposited along the glomerular basement membrane in ...

OUR defense against bacterial infections depends in part on the action of phagocytic leukocytes, which encounter and kill potentially pathogenic microorganisms. A severe reduction in the number or function of phagocytic leukocytes may predispose a person ...

Presentation of Case

First admission. A 27-year-old man was admitted to the hospital because of renal disease.

There was a long history of bronchial asthma. He was otherwise well until three weeks previously, when fever and malaise developed, followed by ...

IN this issue, Weitkamp et al.¹ report major progress in understanding the genetics of depressive disorders (also called affective disorders). They have found that depressive disorders segregate along with HLA in families, which strongly suggests that a ...

The publication of the national surgical study (SOSSUS) in 1975–1976 was a clear invitation to repeat the study within a few years, to discover what would happen to surgical manpower and workloads after the study. The studies of Nickerson and her group ...

IF one puts aside tradition and reexamines the education of the physician objectively, two striking facts emerge. In the first place, there is no recognizable rationale for the sequence in which the basic biologic sciences are taught; secondly, the ...

To the Editor: In a letter in the August 20 issue, Yoshida et al. described how they successfully eliminated anti-M in a severe M-incompatible pregnancy.¹ They went on to recommend this method as a rational means of selectively removing antibody and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The fragile site at Xq27 or Xq28 is recognized as a new cytogenetic marker associated with one type of X-linked mental retardation, which probably accounts for a considerable proportion of mentally retarded males.

Many questions about the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Second neoplasms induced by chemotherapy with alkylating agents are being seen with increasing frequency, especially in patients who have been successfully treated for Hodgkin's disease. Most notable has been the marked increase in acute ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

It is a treasured moment when one finds a book that can pique one's curiosity and maintain its interest because of its subject matter and style. Bad Blood, which recounts in great detail the story of the Tuskegee Syphilis Experiment, is such an effort.

...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

As women with careers in public health and preventive medicine and with expertise in obstetrics-gynecology and pediatrics, we applaud the feminist movement and endorse the concept of the direct involvement of women in their health services. Our concern ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Multiauthored books have become — with a few exceptions—the standard for textbooks and monographs, whether they deal with broad areas of medicine or with narrow, specialized subjects. Many recent monographs are merely the published proceedings of a ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of ...

THE BRAIN

The first World Congress of the International Brain Research Organization will be held in Lausanne, Switzerland, April 1–6. The topic will be "The Brain in Health and Disease."

Contact Dr. L. J. Garey, Institute of Anatomy, Rue de Bugnon 9, 1011 ...

No extract is available for articles shorter than 400 words.

At a time when the general economy is slowing, medical-care costs are rising at a virtually unprecedented rate. This dynamic is leading the Reagan administration to design new cost-control mechanisms for Medicare and Medicaid that would sharply limit ...