ALTHOUGH the incidence of rheumatic fever is declining in the West, degenerative mitral-valve regurgitation, calcific aortic stenosis, and infective endocarditis persist. In the Third World, the incidence of rheumatic heart disease in the young remains ...

THE Epstein–Barr virus (EBV) is a ubiquitous virus of the herpes group that is the causative agent of infectious mononucleosis.¹ Infection is often asymptomatic, and by young adulthood most people have serum antibodies to EBV, which are markers of prior ...

STUDIES in animals^{1 2 3} and human beings^{4 5 6 7} have suggested that the ACTH feedback response to cortisol infusion has two temporally and dynamically distinct phases: an early, rate-dependent phase and a delayed, dose-dependent phase. It has been ...

THE spread of insurance that provides full or nearly full coverage for care is a key factor in the progressive increase in hospital costs.¹ Extensive insurance coverage has broken the link between prices and the actual costs of services, with the result ...

MANY drugs have been used with the expectation of reducing alcohol consumption. A few seem to be associated with a reduction in alcohol use for up to three to six months in some patients, but none is associated with a reduction in alcohol consumption for ...

HEPATIC cytochrome P-450 is important in the metabolism of many drugs.¹ Multiple factors, such as ingestion of inducing agents (e.g., phenobarbital), nutritional state, and the presence of liver disease, influence hepatic levels of cytochrome P-450. ...

OBESITY, or stored energy in the form of excess fat, is a physical expression of a positive energy balance. From time to time, arguments against such a truism have arisen, mainly because most dietetic surveys have failed to show that obese people eat more ...

Presentation of Case

A 63-year-old woman was admitted to the hospital because of left hemiparesis.

She was well until six months previously, when she noticed an enlarging mass in front of the right ear, followed by the onset of pain in that ear. She also ...

Should cardiac catheterization continue to be a routine procedure in patients undergoing surgery for valvular heart disease? Since the introduction of valvular heart surgery over three decades ago, the clinical assessment of a patient with valvular heart ...

Two developments within our society have changed or will change the traditional physicianpatient relationship: the growing practice of the news media to report new research and developments in health-related fields, and the public's increasing conviction ...

WE are rapidly approaching the point at which modern medicine can offer more than society can afford. New approaches are required to decide how much of our limited resources can be devoted to medical care. Such decisions may be made centrally, by ...

No extract is available for articles shorter than 400 words.

To the Editor: Endogenous interferon is found in the brain and cerebrospinal fluid early in the course of viral encephalitis.^{1 2 3 4} Legaspi et al. observed that in herpes simplex encephalitis the levels of endogenous interferon fell progressively in the ...

To the Editor: The neonatal narcotic-abstinence syndrome (NNAS) is characterized by hyperirritability, feeding problems, autonomic instability, and seizures in newborn infants born to mothers who are addicted to methadone, heroin, or other narcotic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The recent Sounding Board by Dr. Roe* fails to make a proper distinction between the "usual, customary, and reasonable" (UCR) program under Medicare and those of the various Blue Shield plans, or to indicate an adequate understanding of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Recent trends toward deinstitutionalization have exposed many deficiencies in the mental-health system in this country. This book presents a model system for the rehabilitation of chronic mental patients ranging in age from children to the elderly. The ...

No extract is available for articles shorter than 400 words.

Modern cardiology is a busy workshop buzzing with sophisticated new machines and techniques. Cleverly designed balloon catheters are inflated throughout the circulation; malignant arrhythmias are induced seemingly at will and then terminated by ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This excellent paperback contains everything that the average surgeon or anesthesiologist needs to know about preoperative pulmonary-function testing. It also gives an excellent account of proved methods of minimizing pulmonary complications associated ...

To many medical students of my acquaintance, the first edition of Stryer's book, published in 1975, is known as "the Dead Sea Scrolls." A larger, much more comprehensive textbook of biochemistry (perhaps the one most widely used in this country) is ...

No extract is available for articles shorter than 400 words.

Anatomic textbooks and atlases of the past two decades have reflected gradual changes in the teaching of gross anatomy. Traditionally lengthy courses have been shortened. Today's students spend less time learning the details of anatomy than did their ...

As applications of decision theory to medicine continue to increase, there is an evident need for a coherent presentation of the principles of clinical decision analysis for students, practitioners, and researchers. Such a work may have several purposes: ...

Biology and Chemistry

Advances in Enzyme Regulation. Vol. 19. Edited by George Weber. 571 pp. New York, Pergamon Press, 1981. $125.

Bacteriophage Assembly. (Progress in Clinical and Biological Research. Vol. 64.) Edited by Michael S. DuBow. 554 pp., ...

CALL FOR PAPERS

Abstracts are now being accepted for the third annual meeting of the American College of Clinical Pharmacy. The meeting will be held in Kansas City on June 25 and 26. The deadline for submission of abstracts is March 1.

Contact Dr. Darwin ...

IN recent months, persons seeking to understand and influence health legislation in Washington have encountered a bewildering maze created by the Congressional Budget Act. Most major actions in Congress this year have been taken through recisions, ...