PYGMIES have normal serum concentrations of immunoassayable growth hormone after a variety of stimuli provoking the release of growth hormone.^{1 , 2} Several clinical and biochemical findings, however, resemble those seen in patients with an isolated ...

TOTAL lymphoid irradiation has been used to treat Hodgkin's disease and non-Hodgkin lymphomas for the past 20 years.¹ Few serious side effects have been observed in long-term follow-up studies. There has been no measurable increase in the risk of leukemia ...

FRACTIONATED total lymphoid irradiation was used to treat 10 patients with severe rheumatoid arthritis that was unresponsive to conventional medications. Total lymphoid irradiation has been used to treat Hodgkin's disease, without serious long-term ...

INCREASINGLY, patients are participating in medical decisions affecting their care and welfare. A previous study has shown that some patients with operable lung cancer would choose radiation therapy over surgery, even though surgery offers a higher ...

THE reduced tensile strength of tissues supporting the ocular lenses, cardiac valves, and aorta in heritable connective-tissue diseases is probably due to a defective organization of collagen. Since multiple biochemical reactions are involved in collagen ...

IN normal persons the plasma aldosterone concentration rises with assumption of upright posture in response to activation of the renin-angiotensin system and to decreased metabolic clearance of aldosterone resulting from reduced hepatic blood flow.¹ In ...

THROMBI form on the surface of pulmonary-artery catheters soon after these devices are inserted into the central circulation.¹ Although complications attributable to such thrombi do not occur frequently, their consequences can be serious: pulmonary ...

CONGESTIVE heart failure, pericardial friction rubs, systolic murmurs, nonspecific electrocardiographic changes, and hypotension usually herald cardiac involvement in patients with Whipple's disease and occur after documentation of disease in the small ...

Presentation of Case

First admission. A 54-year-old man was admitted to the hospital because of a left-sided headache.

He was well until 18 years earlier, when a routine x-ray film of the chest revealed an infiltrate. A tuberculin skin test was positive, ...

In this issue of the Journal, investigators in Stanford and Boston report that total lymphoid irradiation suppresses joint inflammation in patients with severe rheumatoid arthritis not adequately controlled by standard therapy.^{1 , 2} Evidence of decreased ...

The Marfan syndrome was the "founding member" of the heritable disorders of connective tissue.¹ Although this nosologic category has expanded to subsume a rich diversity of diseases involving fibrous connective tissue and ground substance, the Marfan ...

The discovery of primary aldosteronism sparked an intensive search for this syndrome in patients with hypertension. It is now generally accepted that primary aldosteronism is an infrequent cause of hypertension, yet this relatively rare disease has been ...

To the Editor: Fisher et al. compared the use of melphalan (lphenylalanine mustard) plus fluorouracil with the use of the antiestrogen tamoxifen plus melphalan and fluorouracil in a large trial of adjuvant therapy in 1863 women with primary breast ...

To the Editor: Now that there is direct evidence of a reduction in acetylcholine synthesis in Alzheimer's disease^{1 , 2} as well as a clinical response to an acetylcholine precursor in some patients,³ it can be anticipated that the clinical testing of ...

No extract is available for articles shorter than 400 words.

To the Editor: Hui and Conolly reported on a patient with disseminated breast carcinoma and postural hypotension that they suggested was due to dysfunction of the sympathetic nervous system (June 11 issue¹). Their patient's supersensitivity to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: According to his Sounding Board article in the July 2 issue, Dr. Jonas believes that the Board of Regents of New York State, in devising regulations to govern hospital clerkships for United States citizens enrolled in foreign medical ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The three books included in this group review deal with important subjects at the interface of medicine and society. We might call this area "dollars and politics in health-care policy."

Thompson's monograph on Health Policy and the Bureaucracy has the ...

The title of this short book conveys the author's conclusion that a presidential science adviser cannot be effective. Drawing on his experience in the White House Office of Science and Technology, Dr. Burger traces the evolution of the science adviser's ...

The title implies that this book is an exposé of Soviet medicine. It is written for the popular market, and except for a rather marked pretense of special knowledge related to being at the fringe of the American-Soviet health-exchange program, it does not ...

No extract is available for articles shorter than 400 words.

The environmental approach to health is updated in this systems analysis of current public policy. The author follows in the tradition of Lillian Ward, the public-health nurse who, in founding the early settlement-house movement at the turn of the century,...

No other element of public policy, not even national security, is as pervasive, complex, and controversial as energy. Energy issues involving manifold conventional and unconventional technologies go to the center of the economic and social (and therefore ...

"stand at the center of national domestic policy." Inevitably, this system of governmental grants has substantially transformed the organization, procedures, and politics of Congress, of federal agencies, of state and local governments, and especially of ...

No extract is available for articles shorter than 400 words.

Microbiology

Control of Hospital Infection: A practical handbook. Second edition. Edited by E. J. L. Lowbury, G. A. J. Ayliffe, A. M. Gesses, and J. D. Williams. 325 pp. Philadelphia, J.B. Lippincott, 1981. $26.

Infectious Diseases Case Studies. Third ...

CANCER

A symposium entitled "Current Concepts in Cancer Management: Successful Treatment and Its Consequences" will be held at the Fairmont Hotel in San Francisco on November 13 and 14. The fee is $200.

Contact Claire Zellerbach Saroni Tumor Institute of ...

Major changes in the federal government's relations with medical education are evolving under the pressures of dwindling resources and the Reagan administration's intent to transform government's role into that of intervenor and funder of last resort. ...