IN recent years much progress has been made in the treatment of acute lymphoblastic leukemia. At present approximately half the patients are in continuous complete remission, five years after diagnosis. The prolonged survival of children with acute ...

THE use of anticonvulsants in children may be hazardous, but it is based on the premise that the risk of recurrent seizures outweighs the risk of adverse effects of medication. It would be highly desirable to define a point in the treatment of children ...

THE past 10 years have witnessed a marked increase in the number of women in medical schools at the student, faculty, and administrative levels. As a new decade begins, it is appropriate to assess the progress that women have made in academic medicine and ...

CHRONIC idiopathic (or immune) thrombocytopenic purpura (ITP) is a syndrome characterized by persistent thrombocytopenia caused by a circulating antiplatelet factor that results in platelet destruction by the reticuloendothelial system. It seems likely ...

AS limits of nutritional-support programs are tested, the tendency is to simplify regimens for nutrition, to exhaust means of enterai and peripheral-vein supplementation before resorting to central parenteral nutrition, and to scrutinize the advocacy of ...

SUBACUTE sclerosing panencephalitis (SSPE) is a slowly progressing disease of the central nervous system of children and young adults, caused by a persistent measles-virus infection. Patients with SSPE have high levels of antibodies to measles virus in ...

Presentation of Case

A 33-year-old man was admitted to the hospital after a vehicular accident.

He was well until the evening of admission, when he reportedly drove his automobile into a tree. Rescuers found him lying adjacent to the vehicle and brought ...

Women in medicine tend to evoke extreme views. On the one hand it is argued that women in medicine are simply more trouble than they're worth, that they ask too many special favors, are somehow not quite serious, and probably should be home with the ...

BY the mid-1940s the number of internship positions was almost twice the number of graduates from United States medical schools. Institutions and programs that had more applicants than positions and that confidently expected to have acceptances from their ...

The National Resident Matching Program (NRMP) was founded to bring fairness and order to a previously chaotic application process for internships. However, the current computer algorithm that generates the matches treats students and programs differently, ...

All sickness arrives on wings and departs limpingly. — French proverb

Massachusetts has been free of louse-borne typhus (epidemic typhus) for more than three decades. According to the Centers for Disease Control (CDC), the last known case of epidemic ...

To the Editor: The article in the January 8 issue by Shekelle et al.¹ has certainly resulted in a tempest of media headlines. Jane Brody of the New York Times — on the same day — led the parade with a front-page headline, "Long-Term Study Links ...

No extract is available for articles shorter than 400 words.

To the Editor: The Journal has had an important role in introducing Swan–Ganz catheters and describing their complications.^{1 2 3 4} We wish to report two cases of a known complication of this procedure, hemoptysis,^{5 , 6} caused in an unusual way: by ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Recent reviews have emphasized the severe azoospermia that occurs in postpubertal male patients after treatment of Hodgkin's disease with MOPP (mechlorethamine, Oncovin [vincristine], prednisone, and procarbazine).^{1 2 3 4 5 6} Some recovery ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I read with interest the letter by Vekemans et al.¹ on chromosomal mosaicism on amniocentesis as a possible indication for fetoscopy. It is misleading to imply that fetoscopy can confirm "pseudomosaicism." According to the criteria of Boué ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

IN late September of 1980 an international meeting was held in Sicily to mark the centenary of Metchnikoff's discovery of the role of phagocytosis in the maintenance of health. His experiments were conducted in Messina, Sicily, and they brought ...

In a time when the word "regulation" triggers rancorous rhetoric, this publication from the Academy of Political Science of New York is a constructive primer. Regulation is pervasive in health care. Its long-standing areas of impact include the licensing ...

This is an exciting and ambitious book whose scope and importance are belied by its somewhat chatty title. Temin not only reviews the history of drug regulation in this country but also elaborates on an innovative and provocative model of human behavior ...

No extract is available for articles shorter than 400 words.

Mastery of the means to mine, smelt, refine, fashion, and alloy metals has been critical to the advance of civilization. However, there has always been a price for such progress. The classical Greeks and Romans recognized that excessive exposure to lead ...

In an age when specialization has fragmented skill and knowledge, Victor Herbert, M.D., J.D., is a man for the season. Having distinguished himself as attorney, physician, and nutrition scientist, with Nutrition Cultism Herbert now excels as a consumer ...

No extract is available for articles shorter than 400 words.

The first edition of Dr. Grossman's textbook appeared in 1974.

The introduction, then as now, stated its aim as "instruction of physicians training to become cardiologists." The first edition succeeded in that goal to an admirable degree, and the second ...

In Correlative Neuroradiology an effort has been made to use the modes of neuroradiologic diagnosis, mainly computed tomography (CT) and cerebral angiography but also pneumoencephalography, in a system that facilitates the location of intracranial lesions ...

No extract is available for articles shorter than 400 words.

Biology and Chemistry

Fundamental and Clinical Bone Physiology. Edited by Marshall R. Urist. 416 pp., illustrated. Philadelphia, J.B. Lippincott, 1980. $38.50.

Isozymes. (Current Topics in Biological and Medical Research. Vol. 4.) Edited by Mario C. ...

INTERNAL MEDICINE

A course entitled "A Review of Recent Advances in Internal Medicine" will be held at the Boston Park Plaza Hotel, June 1–5. The fee is $325.

Contact Mrs. Emelie S. Born, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA ...