INFECTIONS are a major cause of morbidity and mortality during periods of granulocytopenia in patients with acute leukemia.¹ The infections are primarily due to invasion by colonizing aerobic organisms at sites of mucosal damage; half are caused by ...

LONGITUDINAL studies in women have established that bacteriuria is frequently preceded by colonization of the vaginal mucosa with the organism responsible for the infection.¹ Cultures obtained from patients between their episodes of bacteriuria showed ...

THE question of whether circulating vasopressin can cause or contribute to hypertension in human beings has provoked debate¹ primarily because of evidence that vasopressin has an important role in some forms of hypertension in animals (see Discussion). ...

THE Harrison Narcotic Act, which sought to control the use of addictive drugs through revenue measures, came into effect on March 1, 1915. On that date the federal government initiated a national campaign against physicians and pharmacists who ...

EXCELLENCE in medicine may depend not so much on total numbers of physicians as on an operational balance between physicians readily available in primary care and family practice and their support by consultants in special fields of learning. Long a ...

THE action of insulin at the cellular level may be modified by alterations in insulin receptors or in the multiple steps distal to insulin receptors. An interesting new subset of diabetic diseases related to insulin receptors contains those in which ...

WE report the occurrence of state-dependent dyskinesia in two rapidly cycling manic-depressive patients. Marked oral, buccal, lingual, and associated dyskinesias consistently recurred during depression and essentially disappeared during mania over the ...

Presentation of Case

A 37-year-old man was admitted to the hospital because of hemoptysis and a pulmonary infiltrate.

He was well until two months earlier, when symptoms of a respiratory-tract infection developed, accompanied by hemoptysis. An x-ray film ...

"Unfortunately, the official USP [United States Pharmacopeia] name for the antidiuretic hormone is Vasopressin." So states the 1965 edition of Goodman and Gilman's Pharmacological Basis of Therapeutics, describing antidiuretic hormone.

A great majority of ...

Opiate dependence has been a problem in America for over 100 years. It drew the editorial attention of 19th-century writers,¹ and that interest has continued to the present. Thus, a historical approach such as that taken by Musto and Ramos in this issue ...

Medical subjects hold a fascination for the reading public. The reasons are clear: medical fiction and nonfiction deal with issues of life and death, concern themselves with human beings under stress, reveal hidden worlds (e.g., the intricacies and ...

Lewis Goldfarb, a young government lawyer living in Reston, Virginia, needed a title search for his new home and discovered that all the lawyers in the county quoted the same fee. In checking with the local bar association, he learned that these figures ...

The Surgeon General's report for 1979, Healthy People,¹ contains the following paragraph:

Although evidence keeps mounting that certain food factors and current dietary habits may be linked with health problems as diverse as heart disease, tooth decay, ...

No extract is available for articles shorter than 400 words.

To the Editor: Halsted developed the radical mastectomy as a result of his belief that breast cancer spread centrifugally to the regional lymph nodes, which acted as filters, producing temporary arrest of the growth.¹ This untested hypothesis became ...

To the Editor: We recently detected a high level of terminal deoxynucleotidyl transferase (TdT) activity in bone-marrow serum samples from four TdT-positive patients with leukemia. TdT activity was assayed with a slight modification of the procedure ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We and others have demonstrated that in patients in whom acute nonlymphocytic leukemia develops after cytotoxic therapy for a primary neoplasm (often malignant lymphoma), an aneuploid clone is frequently present in their leukemic cells.^{1 2} ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The paper by Pearson et al. on "The Born-Again Spleen" (June 22, 1978 issue)¹ and subsequent letters in the Journal ² stimulated us to make a prospective study of the incidence and location of accessory splenic tissue. Blaustein and Diggs ...

No extract is available for articles shorter than 400 words.

The receipt oj the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

The Journal solicits reviews of ...

MEETING OF THE AMERICAN MEDICAL WRITERS ASSOCIATION

The New England Chapter will present a "Medical Communicators Forum" at its dinner meeting on Wednesday, May 20, at Dandelion Green in Burlington, Mass.

Contact Judith Linn, New England Chapter, American ...