IT has been suggested that long-term beta-adrenergic blockade may reduce mortality in patients surviving acute myocardial infarction. However, in clinical trials reported to date, either there has been failure to show any overall benefit^{1 2 3 4} or the ...

ALTHOUGH dissolution of cholesterol gallstones has been undertaken during the past decade, ^{1 2 3} noninvasive differentiation of these stones from pigment stones has not been highly reliable. Current criteria for the selection of patients for medical ...

IMMUNE homeostasis is maintained through a tightly controlled balance between inducer and suppressor T-cell subsets in several species.^{1 , 2} In human beings the T4 and T5 antigens are expressed on inducer and suppressor subsets, respectively. T4⁺ T cells ...

AN increasing number of patients have been diagnosed as having biotin-responsive multiple carboxylase deficiency.^{1 2 3 4 5 6 7 8} This genetic disorder involves defects in the metabolism of biotin and produces deficiencies of at least three biotin-...

BIOTIN deficiency has been documented in human beings only in association with prolonged ingestion of raw egg white. In this paper, we report that clinically important biotin deficiency occurred in a child with short-gut syndrome during parenteral ...

CHROMATOGRAPHY of hemolysates of red cells resolves four minor hemoglobin components from the main hemoglobin A (HbA) fraction. These minor components — HbA_1a1, HbA_1a2, HbA_lb, and HbA_1c — collectively referred to as the HbA₁ fraction, make up ...

SOME patients with primary (immunoglobulintype) amyloidosis acquire a coagulation disorder characterized by factor X deficiency^{1 2 3 4 5 6 7 8 9 10 11 12 13} and occasionally factor IX deficiency.^{12 , 13} These patients may have hemorrhagic complications ...

Presentation of Case

A 39-year-old man came to the hospital because of chronic pulmonary disease and infertility.

The patient was healthy until the age of eight years, when he began to have repeated bouts of purulent sinusitis and pneumonia. Between these ...

The large international trial of practolol¹ and the smaller Swedish study of alprenolol² suggested that the number of cardiac deaths after myocardial infarction could be reduced by long-term beta blockade. Why, then, have physicians been reluctant to use ...

Biotin deficiency is an entity that was once virtually ignored in clinical medicine. It has recently been attracting renewed interest, primarily from pediatricians, because of the progress made in the study of inborn metabolic disorders. This interest is ...

Sharp-eyed readers of the Journal will notice that something new has been added in this issue. For the first time we are soliciting book reviews by volunteers from our readership (see page 854).

Each year the Journal receives almost 2000 new titles from ...

IN this brief essay I wish to make two points: that academic existence is no longer threadbare and that academic medicine is no longer genteel.

Although I do not foresee a quantitative peril to the academic physician, I do fear that the quality of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A sobering development in oncology has been the occurrence of secondary hematologic neoplasms in patients who were treated for a primary tumor and apparently cured. Acute leukemia as a terminal event has been described in patients treated ...

To the Editor: Gardnerella (Hemophilus) vaginalis, an agent associated with vaginitis, rarely causes disease in men. The following case represents an unusual localization of infection with this organism.

A 37-year-old married man had pain in the left ...

No extract is available for articles shorter than 400 words.

To the Editor: The recent medical literature has advocated the determination of pleural-fliuid chemistry to distinguish between uncomplicated parapneumonic effusions and effusions requiring thoracostomy-tube drainage.^{1 , 2} Light et al.² recently reported ...

To the Editor: Norfleet et al. reported in their letter in the February 21, 1980, issue that gastric aspirates from patients taking cimetidine tablets produce a false-positive Hemoccult reaction (Smith-Kline Diagnostics, Sunnyvale, Calif.) if the gastric ...

To the Editor: We would like to describe a patient with iron-deficiency anemia, an unusual pica, and an esophageal web.

A 53-year-old woman presented with a dry mouth, cracked lips, and a swollen, painful tongue. One year before, she had had difficulty ...

To the Editor: Terminal deoxynucleotidyl transferase (TdT), an enzyme that catalyzes the addition of deoxynucleotides to the 3'-OH end of oligonucleotides or polydeoxynucleotides, has become an important marker for the classification of acute and chronic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Books such as this one are often the sole surviving vestige of some meeting or symposium convened by cronies who report the same material to each other at least once a year. The outcome can be described thus: "What we don't understand we explain to each ...

Twenty years ago, students and clinicians alike would have considered foreign the concept that the gastrointestinal tract was part of the endocrine system. Now all parties acknowledge that the gastrointestinal tract may be the most prolific of the hormone-...

The Practice of Cardiology is an important addition to medical scholarship and fills a vacuum by providing a relatively short but authoritative treatment of major cardiologic topics. The practicing physician is given access to comprehensive but not ...

At first glance this book resembles a smaller version of Pickering's classic High Blood Pressure, which for many years was a bible to many of us involved in hypertensive disease. It has many of the same chapter headings, and it is a British production. ...

Obstetric-Ultrasound Quadriga

Obstetric ultrasound is a procedure without a clearly defined identity. Should it be part of radiology, because it involves diagnostic imaging? Or should it be part of obstetrics, perinatology, or neo-natology, because of the ...

The 16th edition of Williams Obstetrics, like its predecessors, covers every facet of reproduction, beginning with the anatomy of the female reproductive tract and the pathophysiology of ovulation, culminating in the delivery of the infant and methods of ...

No extract is available for articles shorter than 400 words.

Knowledge of reproductive endocrinology has increased remarkably in recent years. Although this topic is dealt with in books on general endocrinology and on gynecology, its importance clearly merits the emphasis that can be achieved from devoting a single ...

Anatomy

Basic Anatomy for the Allied Health Professions. By Royce L. Montgomery. 455 pp., illustrated. Baltimore, Urban and Schwarzenberg, 1980. $19.50.

Carletons Histological Technique. Fifth edition. Edited by R. A. B. Drury and E. A. Wallington. 520 ...

GRANTS IN NUTRITION AND AGING

ITT Continental Baking Company of Rye, N.Y., is offering research initiation grants in nutrition and aging within the program of Nutrition Education for Older Americans. The deadline for application is May 1.

Contact Dr. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.