alpha1-antitrypsin (AAT), the major serum protease inhibitor, is a glycoprotein synthesized by the liver. Over 24 different, inherited molecular variants have been identified and named according to their electrophoretic mobility.^{1 , 2} The inheritance of ...

THE use of unopposed estrogen therapy in postmenopausal women is known to increase the risk of endometrial carcinoma.^{1 , 2} Some evidence suggests that combined therapy with both estrogen and progestogen decreases the risk.³ Two main groups of progestogens ...

ESCALATING costs of education have increased the number of students requiring financial assistance to complete the M.D. degree, as well as the amount of the individual debts. Although there are many surveys describing how medical students finance their ...

Elastin, a component of connective tissue, is present in virtually every organ of the body. Its role is unique and undoubtedly important, even though it may make up only a small percentage of a tissue. Its role is being appreciated increasingly in the ...

AUTOANTIBODIES may damage human cells through a variety of mechanisms, including complement activation and IgG-dependent phagocytosis.¹ Antibodies can also cause lysis of cells by lymphocytes. This lymphocyte-mediated cytotoxicity depends on IgG antibody ...

HYPERTHERMIA is a new method of treatment receiving increasing clinical attention in cancer therapy. Its efficacy has been well demonstrated in animals, but its indications, contraindications, and appropriate place in cancer therapy have yet to be ...

ISOTOPIC labels attached to various blood cells have been used for years to study the course and kinetics of blood components in vivo. The use of such labeling in granulocytes to evaluate transfusions or to localize infections has met with uncertain ...

THE California Supreme Court continues to puzzle many medical-law commentators with a succession of controversial decisions. If appellate judges are expected most of the time to provide cool reason and clear logic in analysis and results, then the ...

Presentation of Case

A 47-year-old woman was admitted to the hospital because of abdominal pain and weight loss.

She was well until four months earlier, when she began to have crampy pain in the epigastrium that was unrelated to the ingestion of food and ...

IN 1662 John Graunt, a London haberdasher, published his magnum opus, Natural and Political Observations... Made upon the Bills of Mortality, and thereby established the field of epidemiology.¹ Graunt brought to light a diversity of facts about human life ...

ON October 23, 1980, the New York Board of Regents adopted a policy of state accreditation of foreign medical schools to facilitate the ability of United States citizens studying in these schools (USFMSs) to participate in clinical clerkships and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Membranous nephropathy is believed to be an immune-complex disease.¹ However, in only a few instances have an antigen and the corresponding antibody been observed in the lesions. We describe a case of membranous nephropathy associated with ...

No extract is available for articles shorter than 400 words.

To the Editor: In the October 30 issue, the Coronary Drug Project Research Group presented a thoughtful analysis of mortality in relation to adherence and cholesterol response. Two kinds of comments are warranted — the first is related to their analysis, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

IT is widely assumed that most important drugs are discovered through academic research. Indeed, in the case of the antihypertensive drugs credit has been allotted both to the universities and to government, as shown by such encomiums as the Lasker ...

Surgeons in academic training programs think of inguinal, femoral, and umbilical hernias as the training ground for the first-year surgical resident fresh from medical school. True, a surgeon may commence with lymph-node biopsy, saphenous-vein ligation, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Hemodynamic Monitoring of the Critically Ill presents the collected papers from a symposium on this topic held in Toronto in 1978. Part 1 deals with technology, physiology, and clinical considerations; Part 2 describes applications of monitoring in ...

No extract is available for articles shorter than 400 words.

Since the first edition appeared in 1935, Gradwohl's Clinical Laboratory Methods and Diagnosis has served several generations of physicians and scientists as a reference and teaching textbook in laboratory medicine. It has been 10 years since the previous ...

Medicine

Cardiovascular

Cardiovascular Risk Factors in Children. By Gerald S. Berenson. 452 pp., illustrated. New York, Oxford University Press, 1980. $29.50.

Clinical Pharmacology of the Beta-Adrenoceptor Blocking Drugs. By William H. Frishman. 221 pp. ...

CLINICAL PHARMACOLOGY FELLOWSHIPS

The Pharmaceutical Manufacturers Association Foundation offers fellowships in clinical pharmacology for 1982. A recipient may elect to activate the award July 1, 1982 or July 1, 1983. The deadline for application is ...

No extract is available for articles shorter than 400 words.