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December 25, 1980  Vol. 303 No. 26

Original Articles
1493-1498

DIABETES mellitus is a heterogeneous group of diseases.1 Even the insulin-dependent form appears to have more than one cause.2 , 3 In patients with insulin-dependent diabetes mellitus (IDDM) there is a marked decrease in the number of insulin-containing ...

1499-1502

SULFASALAZINE is effective in the treatment of ulcerative colitis.1 , 2 The drug is split by gut bacteria in the colon into sulfapyridine and 5-aminosalicylic acid. Both compounds are primarily conjugated in the liver to their corresponding acetylated ...

1503-1507

PRIMARY aldosteronism is readily diagnosed in patients with hypertension by the findings of persistent hypokalemia, elevated plasma or urinary aldosterone levels, and suppressed plasma renin activity.1 Recognition of such patients is important since ...

Special Article
1507-1511

    IN this George W. Gay Lecture, specifically designated as "upon medical ethics," I shall focus on three issues. The first, an example of intergroup tensions, deals with the common accusation that bioscientists are arrogant, i.e., that they are ...

    Medical Intelligence
    1511-1514

    HYPERPROLACTINEMIA is a relatively common clinical problem, occurring in more than 25 per cent of women who present with secondary amenorrhea.1 , 2 Amenorrhea, anovulation, and galactorrhea are well-established clinical sequelae of hyperprolactinemia in ...

    1514-1517

    IN the past decade, it has become apparent that the immune response is precisely regulated.1 2 3 4 5 This regulation operates at several levels and determines whether there will be an immune response to an antigen, what the magnitude of the response will ...

    1517-1519

    I shall hold this court if I hold it in blood. I shall live as a judge, or die as a general.

    THESE are scarcely words that one might expect from the mouth of a physician, but they were the words of a man who practiced medicine in Massachusetts in colonial ...

    1528-1531

    I can still remember my first meeting with Dr. Garland, which took place in his office on the Fenway, in April 1952. I was on my first visit to the United States as a traveling fellow and, having been editor of a small medical journal that had literally ...

    Case Records of the Massachusetts General Hospital
    1519-1526

    Presentation of Case

    First admission. A 60-year-old woman was admitted to the hospital because of congenital heart disease.

    A heart murmur and skeletal anomalies were noted shortly after birth. Her early years were uneventful and free of symptoms. At the ...

    Editorials
    1527-1528

      A cheerful tradition dictates that at this season we send you our warmest greetings. We follow this amiable practice with pleasure and add our heartfelt thanks to all our readers, contributors, and reviewers for their lively, if sometimes contentious, ...

      1528

      No extract is available for articles shorter than 400 words.

      Correspondence
      1531-1532

      No extract is available for articles shorter than 400 words.

      1532-1533

      No extract is available for articles shorter than 400 words.

      1533

      No extract is available for articles shorter than 400 words.

      1533

      No extract is available for articles shorter than 400 words.

      1533-1534

      No extract is available for articles shorter than 400 words.

      1534

      No extract is available for articles shorter than 400 words.

      1534

      To the Editor: In their letter in the September 18 issue, Insel and his colleagues question whether a consent to lumbar puncture is "informed" if a clinical investigator fails to tell a research subject about the approximately 0.1 per cent risk of ...

      1534-1536

      No extract is available for articles shorter than 400 words.

      Book Reviews
      1536

      No extract is available for articles shorter than 400 words.

      1537

      No extract is available for articles shorter than 400 words.

      1537

      This textbook distills a massive amount of information so that students will understand the concepts of orthopedic examination, diagnosis, and treatment. Information is provided clearly and concisely.

      The initial chapter gives the medical student, ...

      1537-1538

      This is a readable, concise, well-referenced book that succeeds in providing an update and review of 14 topics in obstetrics and gynecology. In bringing together chapters written by 22 authors, the book achieves the success of a well-organized ...

      1538

      Ultrasonography has won wide acceptance recently as a valuable noninvasive diagnostic tool. Its successes derive from new instrumentation, expanding applications, and improved accuracy, all of which have continued unabated since sonography came into ...

      1538

      No extract is available for articles shorter than 400 words.

      1538-1539

      No extract is available for articles shorter than 400 words.

      1539

      Man's best friend and worst enemy, alcohol, has been used for religious ritual and mind alteration for over 5000 years. Problems associated with its use date back to the earliest days of recorded history, yet treatment and attitudes toward alcohol have ...

      1539

      No extract is available for articles shorter than 400 words.

      1539-1540

      The book on the American system of health care by Marshall W. Raffel, professor of health planning and administration at Pennsylvania State University, is faithful to its title. It is designed to be a resource for students in health administration and ...

      1540

      No extract is available for articles shorter than 400 words.

      Books Received
      1540-1541

      The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

      Medicine

      Cardiovascular

      A Synopsis ...

      Notices
      1541

      PEDIATRIC NEPHROLOGY

      The University of Miami School of Medicine will sponsor the "8th Annual Symposium in Pediatric Nephrology: Current Concepts in Diagnosis and Management" to be held at the Sheraton–Bal Harbour Hotel in Miami, January 25–29.

      Contact Dr. ...

      Washington Report
      1542-1544

      Given President-elect Reagan's commitment to cut taxes and increase military spending while reducing the total budget, federal health programs — now running at about 10 per cent of all federal spending — may seem to rank high as sacrificial prospects. But ...