NEOPLASMS originating in the islet cells of the pancreas present a therapeutic challenge to medical and surgical oncologists. In early stages, their presence is frequently heralded by the dramatic and bizarre manifestations of endocrine hyperfunction. In ...

DURING the past several years, the use of estrogen preparations by postmenopausal women has been shown to retard the age-related decrease in bone density.^{1 2 3} However, loss of bone density itself is of little clinical relevance; it is important primarily ...

THE association of viral infections with acute episodes of wheezing in patients with and without previous episodes of bronchiolitis or asthma is well recognized.^{1 , 2} Respiratory syncytial virus (RSV) is the infectious agent most commonly associated with ...

SINCE its discovery in 1934, ¹ phenylketonuria (PKU) has become widely recognized as an inborn error of metabolism that may cause mental retardation and other manifestations of brain damage.² It is now apparent the nonphenylketonuric offspring of mothers ...

TRANSCOBALAMIN II, a 38,000-dalton plasma protein, has a single binding site for cobalamin (vitamin B₁₂) and functions as the major protein for transporting cobalamin to various tissues.^{1 2 3 4} Table 1 lists the characteristics of four cases of hereditary ...

METRONIDAZOLE provided the first effective cure for trichomoniasis, a disease that until 20 years ago was said to cause more suffering than cancer.¹ The drug was placed under a cloud, however, when, after nearly 15 years of widespread use, attention was ...

Presentation of Case

A 38-year-old woman was admitted to the hospital because of a pulmonary infiltrate.

She was well until eight years earlier, when bloody diarrhea occurred and a diagnosis of ulcerative proctitis was made. Sulfasalazine was prescribed; ...

IN an editorial in the July 3 issue of the Journal, Julius Krevans called attention to some important legislative proposals that dealt with the future of the National Institutes of Health (NIH).

These proposals (H.R.7036, the Health Research Act of 1980, ...

The generally expansionist policies for physician manpower heretofore recommended by medical-manpower commissions and implemented by medical schools, legislatures, and Congress have had serious, unintended effects on access to primary care, on cost, on ...

William Osler was well aware that the patient's bedside was the chief arena of medical education. He told us that there should be "no teaching without a patient for a text, and the best teaching is that taught by the patient himself." ¹ Henry Christian ...

To the Editor: In their article on "Management of Hypertension in the Elderly" in the June 19 issue, O'Malley and O'Brien recommend that elderly patients should not be treated for hypertension until the diastolic blood pressure is 110 mm Hg or more, ...

No extract is available for articles shorter than 400 words.

To the Editor: Cytotoxic drugs damage the testis and frequently cause azoospermia.^{1 , 2} In contrast, androgen production is only slightly affected in adults, ³ although more so in adolescents.⁴ Men who survive acute leukemia have rarely fathered children,...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We would like to report on the course of a case of propylene glycol intoxication accompanied by development of lactic acidosis.

The patient, a 58-year-old man who was known to have chronic schizophrenia, was admitted to the hospital in a ...

To the Editor: We congratulate Mach et al. for their report in the July 3 issue on the unequivocal scintigraphic identification of tumor sites in 11 of 27 patients given [¹³¹I]-labeled antibody to carcinoembryonic antigen (CEA) — a method that has been ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The third edition of Community Health, Preventive Medicine and Social Services was published in early 1975, a few months after a periodic reorganization of the National Health Service and local governmental services in Britain. This fourth edition ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In this practical approach to parenteral nutrition, the author has attempted a monumental task: to collate most of the references in the rapidly growing field of parenteral nutrition, with the emphasis on the practical, presumably to serve as a resource ...

In the foreword, Prof. Brian Abel-Smith, a distinguished British economist, describes this book as "the most comprehensive and fascinating interpretation of the politics of medical organization that has ever been published." I am inclined to agree, ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Biology and Chemistry

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OBSTETRICS

A "High Risk Obstetric Seminar" will be held at Vanderbilt University Medical Center in Nashville on December 12 and 13.

Contact Continuing Medical Education, 3200 West End Ave., Suite 306, Nashville, TN 37203; or call (615) 322–2716.

...

Breast cancer is hormonally mediated and estrogens are the prime agents in tumor expression; estrogen action may be unopposed by progesterone at certain critical periods in a woman's life. This was the main conclusion of the first of four meetings at ...