THE influence of advancing age on the cardiovascular response to exercise has been the subject of considerable study for many years. As early as 1929, Master and Oppenheimer described an age-related decline in the foot-pounds of work performed in the two-...

THE recurrent, painful crises of sickle-cell anemia, which are the major cause of morbidity in this disease, result from what has been termed "a vicious cycle of erythrostasis." ¹ In the hypoxic environment of the capillary bed, hemoglobin S is ...

THE anthelmintic tetramisole and its levoisomer, levamisole, increase cell-mediated immunity in laboratory animals^{1 2 3 4 5 6 7} and human beings.⁸ Studies in animals indicate that these drugs inhibit tumor growth and increase long-term survival in some, ...

ALTHOUGH 1980 is the 100th anniversary of the first description of the eosinophil, ¹ whose levels are markedly elevated in the blood of patients with certain helminthic infections, the precise role of these cells in the host's response to parasitic ...

MACROPHAGES facilitate a variety of thymus-dependent immunologic phenomena in human beings and laboratory animals; thus, these cells are essential for the development of cellular and humoral immunocompetence.^{1 ,}1a Their role in T-cell and B-cell function ...

IN 1966 Laron and his associates described a severe form of dwarfism associated with high levels of circulating immunoreactive human growth hormone.¹ Laron dwarfism is usually a familial disorder, and affected persons are generally resistant to the ...

BOTH alcohol consumption^{1 , 2} and physical activity³ are inversely related to coronary heart disease. In addition, both are positively associated with increased levels of high-density-lipoprotein cholesterol (HDL-C), ^{4 5 6 7 8} high levels of which protect ...

Presentation of Case

First admission. A 43-year-old man was admitted to the hospital because of ataxia.

He was well until one year earlier, when herpes zoster appeared in the right eighth thoracic distribution and cleared within two weeks. Seven months ...

Recent studies have shown that aging has a selective effect on specific aspects of cardiovascular function and on the response to pharmacologic agents. Basal contractile function is well maintained in both isolated cardiac muscle¹ and intact hearts from ...

Publication of the results of a trial in which levamisole, a chemical that stimulates some components of the human immune system, had no effect on the clinical course of malignant melanoma (see the report of Spitler and Sagebiel in this issue) provides an ...

Resolved, that we agree with Walter B. Cannon's dictum that "What happens in our bodies is directed toward a useful end," what, then, is the useful end of the eosinophil?

Certainly, the eosinophil is a spectacular cell. How is it possible that a cell that ...

Arenstam — Jacob John Arenstam, M.D., of Russell, died on August 1. He was in his 75th year.

Dr. Arenstam received his degree from Boston University School of Medicine in 1932. He was a member of the American Medical Association, the American Academy of ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We report an observation made during a study on hormone-transport patterns in patients with malignant gammopathies. In a 68-year-old man with Waldenström's macroglobulinemia, cortisol was found abnormally bound to gamma globulins.

...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Modern Legal Medicine, Psychiatry and Forensic Science (referred to below as Legal Medicine) is an immense and important tome that is encyclopedic in intent even if it cannot be encyclopedic in depth and breadth. This weighty book (almost 3 kg) does ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Most physicians are aware of the marked increase in cases of imported malaria, typhoid fever, and other illnesses among North American travelers during the past five years. This rise in imported disease reflects both the greater frequency of travel to ...

The appeal of nephrology to many students is the extent to which it can be understood in terms of basic renal physiology and the derangement of normal regulatory mechanisms. This is the approach of Dr. Valtin's text on renal dysfunction, a sequel to his ...

Most investigators working in the field of birth defects are familiar with the first edition of the Compendium, of which this book is an enlarged version. It catalogues in alphabetical order over 1000 diseases, malformations, and syndromes. The term "...

This concise book was prepared largely by urologists, medical oncologists, and radiation oncologists at the University of Indiana as part of the Cancer Management series edited by Luther Brady and Vincent DeVita. It is an excellent, comprehensive review ...

The nondermatologist often finds cutaneous diseases difficult to diagnose because of the elusive and often untenable concepts of cutaneous morphology and pathophysiology. Lazarus and Goldsmith should be commended for at least attempting to help identify ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy, Histology, and ...

CERVICAL SPINE RESEARCH

The eighth annual meeting of the Cervical Spine Research Society will be held in Palm Beach, Fla., December 10–13.

Contact Dr. Henry H. Sherk, 2647 Westfield Ave., Camden, NJ 08105.

MUSCULOSKELETAL DISEASE

Long Island Jewish–...