SODIUM and potassium-dependent adenosine triphosphatase (sodium-potassium-ATPase) is the enzymatic expression of the ubiquitous sodium pump, ^{1 , 2} and as such it serves a number of important functions. The pump maintains intracellular sodium and potassium ...

ALTHOUGH the exact nature of the basic defect underlying the classic form of vitamin D–resistant rickets (VDRR)¹ is a matter of continuing debate, it is accepted that its hallmark, hypophosphatemia, is caused by a primary defect in renal transport of ...

THE geographic distribution of physicians continues to be a major concern of public policy. The high degree of specialization among recent graduates has accentuated the fear that areas outside urban centers will remain underserved despite the large ...

MANY pitfalls are encountered in the analysis of data from clinical trials. This is true even of trials that are properly randomized, controlled, and double blind. Among these pitfalls are the following: repeated analysis of the data as they accrue over ...

THE treatment of hirsute women is controversial and often presents a therapeutic dilemma. Mechanical methods (such as shaving or using depilatories) are safe but often unacceptable to the patient, whereas suppression of adrenal or ovarian function may not ...

INTRAVENOUS leiomyomatosis may be defined as the extension into venous channels of histologically benign smooth-muscle tumors arising either from a uterine myoma or from the walls of a uterine vessel.¹ Marshall and Morris² provided the first English-...

THE results of a recent study by Weiss and Sayvetz¹ suggested that women who have used oral contraceptives of the combination type for at least one year have about half the risk of endometrial cancer experienced by other women. Their study also confirmed ...

FOR many years it has been accepted that the practicing physician can maintain his competence only by regular updating. The reading of medical journals, attendance at scientific meetings, and participation in regular hospital educational activities have ...

Presentation of Case

A 27-year-old woman was admitted to the hospital because of dyspnea.

She was well until five weeks earlier, when she began to have pain in the left flank, hip, and thigh. Two weeks before admission progressive dyspnea and a dry cough ...

For the adipose tissues of an animal or a human being to increase, more calories must be ingested and absorbed than are needed to satisfy the organism's metabolic requirements. In normal persons, there is a close coupling between metabolic demands and ...

Equal access to high-quality health services in all geographic areas at an affordable cost is the nation's primary health-policy objective. Attainment requires an adequate supply of physicians in each specialty, an equitable geographic distribution of ...

The intervention trial of greatest benefit to patients satisfies three objectives: validity (its results are true), generalizability (its results are widely applicable), and efficiency (the trial is affordable and resources are left over for patient care ...

To the Editor: In the June 19 issue of the Journal, Hulley et al. demonstrated that fasting plasma triglyceride levels were not an independent risk factor for coronary heart disease in healthy men between the ages of 41 and 61 who were followed for seven ...

To the Editor: The articles by Rubin and Peter and by Klinke and Gilbert in the January 10 issue, describing the beneficial effects of systemic vasodilators in the therapy of pulmonary hypertension, generated a considerable response. In the May 29 issue, ...

To the Editor: In the June 26 issue Cavalli et al. described a man with testicular cancer that developed four years after radiotherapy and chemotherapy for Hodgkin's disease. The authors suggested that the testicular neoplasm arose as a result of the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: It has been found that HLA-B15, B8, and B18 antigens are associated with a gene (or genes) for susceptibility to insulin-dependent diabetes mellitus (IDDM).¹ This association is secondary to a stronger association with DR3 (or DRw8, in ...

To the Editor: If the hypothesis that human insulin-dependent diabetes mellitus (IDDM) may, in some instances, be an autoimmune disorder is correct, ¹ it is reasonable to assume that suppression of the immune response should have a favorable effect on ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

As an instructor in courses dealing with health problems of the less industrialized countries of the world, I am frequently asked, "What is the best general tropical-medicine textbook?" The arrival of Prof. Maegraith's new edition was welcomed; it offered ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This well-written, compact, and concise book instructs the primary-care physician to pay attention to preventive medicine and include it in his practice. It will be instrumental in avoiding the excessive attention of this new specialty to curative, even ...

We now have many paperback synoptic reviews of various specialties in the medical literature. This author seeks to attain a practical, easy to read, and uncomplicated mastery of hematologic therapy. In his preface, Dr. Ungaro states, "The primary concern ...

This book is a collaborative effort between a group of British physicians and surgeons, mainly from Manchester, and a similar group from France, principally Marseilles. In the first section five chapters cover embryology, gross and microscopical anatomy, ...

Professor Bond is eminently qualified to prepare a comprehensive précis on pain "written primarily for medical undergraduates in the clinical years of their studies" and seeking to cover all facets of the subject. Six chapters discuss the anatomic, ...

Drugs of Choice is the 12th edition of a book designed to guide the practicing physician through the maze of available drugs, old and new, and provide sufficient information to select the drug of choice for the patient. In addition to chapters on ...

AMERICAN MEDICAL WRITERS ASSOCIATION

Dr. John P. Callan will speak about his one-year writing fellowship at the American Medical Association at a dinner meeting of the New England Chapter to be held at the Marriott Hotel in Newton, Mass., on November 12.

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