The extent of coronary-artery occlusion during the first few hours of transmural myocardial infarction is poorly understood. Traditionally, reluctance to subject patients to early coronary arteriography has been based on the belief that injection of ...

Thrombocytopenia associated with the administration of heparin has been recognized for over 30 years and has been observed in human beings^{1 2 3 4 5 6 7} and animals.⁸ Reports during the past four years have demonstrated that the problem is widely ...

Hypercholesterolemia, particularly when associated with elevations of low-density lipoprotein (LDL), is widely accepted as a positive risk factor for coronary-artery disease, and most experts recommend therapy to reduce elevated cholesterol levels. In ...

SUBACUTE necrotizing encephalomyelopathy, or Leigh's syndrome, ¹ is a degenerative disorder characterized by progressive deterioration of brain-stem functions, ataxia, convulsions, hypotonia, and failure to thrive. The histopathologic changes are found in ...

Horace Fletcher, a popular 19th-century food faddist who advocated chewing food twice for each tooth, alluded to the possible dependence of absorption on thorough mechanical breakdown of food.¹ However, it is generally believed that chewing has a minor ...

HISTORICALLY, the classification of lymphoid cancer has been based on morphologic assessment with the light microscope. The observation that lymphoid cells can be categorized according to immunologic cell-surface markers has provided an additional, more ...

MINOXIDIL (Loniten), a piperidino-pyrimidine derivative (Fig. 1), is an unusually potent vasodilator of unique value in treating patients with severe hypertension. After 11 years of clinical investigations, it was approved by the Food and Drug ...

Presentation of Case

A 51-month-old girl was admitted to the hospital because of a cough and dyspnea.

She was well until the age of 18 months, when a gait disturbance was observed. Two months later a physician found bilateral papilledema, with retinal ...

When a new naturally occurring substance is discovered, medical researchers are justifiably eager to determine whether abnormalities in its disposition are relevant to disease states. Such investigations are more readily conducted with the opioid peptides ...

The American College of Obstetricians and Gynecologists recently considered a recommendation that all pregnant Rh-negative women be given Rh immune globulin at 28 weeks' gestation to prevent antepartum Rh immunization in the third trimester. Although the ...

Many physicians approach cost-benefit and cost-effectiveness analysis (CBA/CEA) with something akin to what Sir James Frazer described as "the awe and dread with which the untutored savage contemplates his mother-in-law." ¹ This is unwise and unnecessary. ...

Kelly — Arthur Norbert Kelly, M.D., of Needham Heights, died on July 30. He was in his 65th year.

Dr. Kelly received his degree from Tufts College Medical School in 1941. He was a member of the American Thoracic Society and the American Academy of General ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We described thick, waxy skin in adolescents with long-standing diabetes who also had limited joint mobility, delayed sexual maturation, and statural defect.¹ More recently, the association of limited joint mobility with early ...

No extract is available for articles shorter than 400 words.

To the Editor: The psoralens are well-known photosensitizing compounds that have been increasingly used to treat psoriasis.^{1 , 2} One of them, methoxsalen (8-MOP), has been detected in human lenses as well as in ocular tissues of animals.^{3 4 5} In the lens,...

To the Editor: Our experience with 92 surgically treated patients with Zollinger–Ellison syndrome (ZES), ^{1 , 2} 66 of whom have been followed for five or more years, together with more recent experience with both cimetidine and ranitidine in the treatment ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In 1979 we were invited by the World Health Organization to address the cancer problem in India, as the first recorded joint Soviet-American health mission to a third country. In India the incidence of cancer and its mortality appear to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Upbeat in tone, succinct, and attractive in format, this official report to the public opens with an optimistic declaration: "The health of the American people has never been better." Potential contributions of preventive medicine are identified, with ...

Pioneering research by Masters and Johnson, published in 1966 as Human Sexual Response, ushered in an era of new knowledge about human sexuality. This new book represents an important contribution to the medical literature, and it presents the most up-to-...

Imported diseases are becoming more common in all industrialized societies. Powerful social, political, and economic forces have caused the movement of people from tropical, developing countries to temperate, developed countries, and these people have ...

This compact book is a stark reminder that we inhabit a world divided. The undeveloped tropical countries are desperately short of physicians, lacking in sophisticated medical equipment, and rife with diseases that are now rarely encountered in affluent ...

No extract is available for articles shorter than 400 words.

Nourishing the Humanistic in Medicine is a welcome addition to the recent attempts to address both the ethical problems that have been created by the burgeoning developments in medical science and the varied complaints of the dehumanization of health ...

No extract is available for articles shorter than 400 words.

David Rogers writes from the uncommon perspective of a medical career that includes research in infectious diseases, the chairmanship of a department of medicine (Vanderbilt), three years as a medical school dean (Johns Hopkins), and almost a decade as ...

SPORTS MEDICINE

The University of Hawaii will sponsor a sports medicine course to be held at the Princess Kaiulani Hotel in Waikiki, March 16–20. The fee is $230.

Contact Ms. Joy Lewis, Box CE-CCECS, 2350 Dole St., Honolulu, HI 96822; or call (808) 948–...