THE tendency to form calcium oxalate kidney stones is believed to be related directly to the urinary concentrations of calcium and oxalate and inversely to those of magnesium and citrate.¹ The protective actions of magnesium and citrate reflect their ...

X-LINKED mental retardation is an established clinicogenetic entity.¹ In about 30 per cent of families, ² affected males have the X-chromosomal structural "fragile site" marker, fra(X)(q27) in a proportion of lymphocytes cultured in a specific medium.^{3 , ...}

OVER the past decade, a number of states have established programs to set hospital rates on a prospective basis as a response to rapid increases in health-care expenditures. During this period, several authorities have viewed the evidence on the ...

BECAUSE of its prevalence in women of child-bearing age, systemic lupus erythematous (SLE) has been of particular concern to obstetricians. Recent reports of the clinical features and complications of pregnancy in patients with this disease have appeared. ...

A LARGE and clinically important interaction between digoxin and quinidine is now well documented.^{1 2 3 4 5} The cardiac glycoside digitoxin is extensively used in clinical practice, but its interaction with quinidine has not been definitively evaluated.^{6 ,...}

The possibility that certain tumor viruses are simply laboratory artifacts makes them in some respects more interesting rather than less, because it means that they may be offering us a way of isolating and studying the genes responsible for the cancerous ...

LEYDIG cells, the interstitial cells of the testes, lie between the seminiferous tubules and produce androgenic steroids. The secretion of testosterone in men has been thought to be regulated by a feedback system in which luteinizing hormone from the ...

Presentation of Case

A 10-year-old boy was admitted to the hospital because of an abdominal mass.

He was well until six weeks previously, when he began to complain of intermittent abdominal pain. Four weeks before admission the pain became more severe, ...

This issue of the Journal contains an article by Turner and her colleagues that presents yet another chapter in the rapidly expanding saga of the relation between mental retardation and a cytogenetically detectable change in the X chromosome. The story ...

Hospital cost containment is the most important and vexing health-care issue that the American health-care industry faces today. Current expenditures for patient care in hospitals exceed $60 billion annually, nearly 40 per cent of the amount spent for all ...

To the Editor: In the August 2, 1979 issue of the Journal, we reported the results of a double-blind, placebo-controlled study of the effect of leukocyte interferon on oral and labial herpes simplex virus infection that was elicited by microsurgical ...

No extract is available for articles shorter than 400 words.

To the Editor: Cimetidine is a histamine H₂-receptor antagonist with demonstrated efficacy in duodenal ulcer, Zollinger-Ellison syndrome, and the gastrointestinal sequelae of systemic mastocy-tosis.^{1 2 3 4} Its effects on gastric ulcer and hemorrhagic ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Intraocular pressure (IOP) may rise in patients treated with long-term hemodialysis.¹ This rise in pressure is thought to be part of the cerebral edema that occurs in the dysequi-librium syndrome as a consequence of the rapid drop in serum ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Triiodothyronine (T₃)-toxicosis is a variant of the commonly observed form of thyrotoxicosis in which the clinical syndrome is caused mainly by elevated serum concentrations of T₃. One of the criteria that have been proposed for this ...

No extract is available for articles shorter than 400 words.

To the Editor: Prenatal diagnosis is playing an increasingly large part in health care. Most prenatal diagnostic tests depend on amniocentesis and the subsequent culture of amniotic-fluid cells. Fetal-calf serum is an important component of the medium ...

To the Editor: The interesting observation of Jope et al. (October 12, 1978 issue) that choline accumulates in the erythrocytes of manic-depressive patients treated with lithium carbonate led us to screen 14 such patients, to assess whether there is any ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In accord with a Food and Drug Administration (FDA) regulation¹ that became effective on December 26, 1979, prescription-drug labeling (package inserts) appearing in the marketplace for newly approved drugs now contains one of five ...

No extract is available for articles shorter than 400 words.

This is a highly personalized account of the development of a medical care group at Washington University in St. Louis. The work was defined as a clinical experiment in patient care. In contrast to the usual fee-for-service practice, this was a ...

The number of laboratory tests performed in this country increases substantially each year because of new clinical applications of knowledge and techniques from the basic sciences, automation, and the development of convenient, low-cost services by large ...

All conscientious physicians are plagued by the problem of how to read, digest, and incorporate into practice all the new information in the medical literature. This concern is particularly acute in a subspecialty like nephrology, where the overlap ...

The morphology of diseased tissue as viewed through the microscope is a continuous spectrum. There really are tissues that are neither benign nor malignant; despite refinements in the art, there always will be. The only way one becomes truly familiar with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

An American pediatrician seeing his first patient in a third-world country might be surprised when an illiterate mother presents her child's growth chart to him and points out why she has come: the child's weight for age, in successive measurements, has ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Hall Jackson of Portsmouth, N.H., was undoubtedly a man of "sprightly talents," which he used to the full in peacetime and during the Revolutionary War. He received part of his medical education in London, where he must have acquired his considerable ...

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of tfie sender. Books that appear to be of particular interest will be reviewed as space permits.

Opthalmology

Scott-Brown's ...

RURAL PRIMARY CARE

The National Rural Primary Care Association is seeking papers for presentation at its fourth National Conference to be held in Denver, March 7–12, 1981.

Contact Vicki Coates, NRPCA, Box 1211, Waterville, ME 04901.

LAW AND MEDICINE

The ...

No extract is available for articles shorter than 400 words.