THE natural history of Crohn's disease is highly variable and unpredictable. Because of the high postoperative recurrence rate, surgical resection is indicated only for severe complications or for prolonged debilitation. Medical treatment is therefore ...

INTRAVASCULAR thrombus formation probably has an important role in the pathophysiology of several highly prevalent vascular disorders including myocardial infarction, stroke, and pulmonary embolism.^{1 , 2} Since net thrombus production represents the ...

THE polymerization of deoxygenated sickle hemoglobin (Hb S) is generally felt to be the primary causal factor in the complex pathophysiology of sickle-cell anemia. However, the exact relation between the intracellular polymerization of Hb S, the ...

A MAJOR portion of medical resources in the United States is consumed by a small fraction of patients.¹ This fact, most recently documented by Schroeder,² raises important issues of cost distribution, predictability, preventability, equity in treatment, ...

IT has been seven years since human infections with genital mycoplasmas were reviewed in these pages.¹ Interest in these organisms has increased considerably with a corresponding increase in our knowledge about them. This article will attempt to evaluate ...

THE annual incidence of colorectal cancer in the United States is 100,000 cases, and the five-year survival rate for all stages, 41 per cent, has remained unchanged for the past 25 years.^{1 , 2} Heavy reliance has been placed on use of the rigid ...

CIMETIDINE inhibits microsomal metabolism and hence impairs elimination of oral anticoagulants and the model drug antipyrine from the bloodstream.^{1 , 2}

Diazepam and cimetidine are among the most widely used drugs, and many patients are treated with both ...

Presentation of Case

First admission. A 60-year-old man was admitted to the hospital because of anorexia. He was well until two months previously, when anorexia, fatigue, and dyspnea developed, and he entered another hospital because of a question of ...

The causes of Crohn's disease are unknown, and there is no specific treatment for it. We know that it is a chronic granulomatous disease of the small and large intestines and that it has a peak incidence in the second and third decades and a tendency to ...

Williams and his associates report in this issue that a physical-conditioning program decreased fibrinolytic activity at rest and augmented the rise in fibrinolysis induced by experimental venous occlusion. They suggest that this effect of exercise may be ...

Soon after publications initially describe the actions of new drugs with high maximum effects but low therapeutic indexes, toxic reactions, often undetected in early studies, may appear.¹ Ticrynafen, cimetidine, and amrinone are cases in point.

Why do ...

No extract is available for articles shorter than 400 words.

To the Editor: Runaway pacing, an uncommon complication of permanent pacemakers, is seldom encountered with temporary pulse generators. A rapid ventricular response to a runaway pacemaker is a potentially lethal complication and is associated with high ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In 1978 Levinsky et al.¹ reported the presence of IgG-containing complexes in serum samples from 39 children presumed to have minimal-change nephropathy because of the steroid responsiveness of their nephrotic syndrome. There was a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We have recently analyzed data on the career expectations of women who entered Jefferson Medical College in 1966–1969 and 1970–1973, to identify changes associated with new attitudes toward women's careers and increased enrollment of women ...

To the Editor: A recent article in the New York Times ¹ and a subsequent letter to the editor² gave a misleading account of the odds of gaining admission to an American medical school. According to the article, there are 340,000 applications for 16,700 ...

No extract is available for articles shorter than 400 words.

These two books, seemingly as different as two books could be and still deal with the same human anatomy, do have something in common: They are both encyclopedic.

The Atlas is a picture book of breast diseases, profusely illustrated with remarkable color ...

Both books cover the same general areas, and both are written by authorities with wide experience. Both are profusely illustrated and provide useful information in an aspect of ophthalmology for which relatively little current reference material is ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Public Health and Geographic Medicine

Dengue in the Caribbean, 1977. (Proceedings of a Workshop held in Montego Bay, Jamaica, May 1978). By Pan American Health Organization. 186 pp., illustrated. Washington, DC, Pan American Health Organization, 1979. $8.

URODYNAMICS SOCIETY

"Neurophysiology and Neuropharmacology of Micturition" will be the topic of this year's forum sponsored by the Urodynamics Society. The forum will be held in Toland Hall, Room U142, University of California, San Francisco, on May 17.

...