THE consensus of reports on post-transfusion hepatitis and the use of frozen or washed red cells is that the use of these blood components virtually eliminates the problem.

Bryant¹ reported not a single substantiated case of transfusion-induced hepatitis ...

A 10-year prospective study of the epidemiologic characteristics and natural history of urinary-tract infection was conducted from 1959 to 1968 in Charlottesville, Virginia.^{1 , 2} The relative stability of the population permitted us to follow a group of ...

FOR half a century many cardiac arrhythmias have been successfully treated by the combined use of quinidine and digoxin, despite the considerable risk of adverse reactions.¹ Recently, surprisingly high serum digoxin concentrations have been observed ...

THE rapid advance in medical technology over the past two decades has raised serious questions about patient autonomy and the right to die with dignity. This article will attempt to examine psychologic issues affecting decision making in these areas. ...

MORE than 30 drugs in current clinical use, other than those used in anesthesia, may interfere with neuromuscular transmission. This complication of drug therapy is unusual but has been well documented; over 200 cases have been reported.¹ Awareness of the ...

VANCOMYCIN given by mouth is effective for the treatment of pseudomembranous colitis,^{1 2 3 4} a disease now known to be caused by an exotoxin of Clostridium difficile.^{5 6 7 8} Only one relapse of colitis after treatment with vancomycin has been reported.⁹ ...

A PATIENT with hypertension, hirsutism, hyperglycemia, hypokalemic alkalosis and a transient paranoid psychosis was found to have hypercortisolism and increased excretion of catecholamines secondary to an ACTH-secreting pheochromocytoma. Fluctuations in ...

CLINICAL cardiac electrophysiologic studies are performed to evaluate mechanisms of arrhythmias and their response to therapy.^{1 2 3 4 5 6 7 8 9 10} Lidocaine, injected to provide local anesthesia before insertion of the electrode catheter, can affect the ...

Presentation of Case

A 42-year-old man was admitted to the hospital because of an inguinal ulcer.

He was well until four months earlier, when a "pimple" appeared in the right groin and evolved into a draining ulcer. Nine weeks before admission frontal and ...

Many enzymes (e.g., pepsin) and endocrine hormones (e.g., insulin) are synthesized first in the form of an inactive zymogen, which is then subject to proteolytic cleavage before eventual secretion in active form. By analogy, investigators have focused ...

The Royal Society of Medicine of London has recently held a multidisciplinary symposium on Behçet's syndrome, arranged by Professor T. Lehner of Guy's Hospital and Dr. Colin Barnes of the London Hospital; the transactions are to be published shortly.¹ ...

Experimental evidence is now available demonstrating that the great majority of malignant tumors in animals, as well as the leukemias and lymphomas, are caused by transmissible oncogenic viruses. These viruses are widely disseminated in a variety of ...

DEATHS

Leeder — Eli Emanuel Leeder, M.D., of Brockton, died on March 31, 1978. He was in his 75th year.

Dr. Leeder received his degree from Tufts College Medical School in 1929. He formerly served as president of the medical staff of Brockton Hospital.

He ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We read with interest the recent case report concerning acute hepatic failure in children taking sodium valproate¹ and agree with Temple et al.² that case reports are essential to defining the toxicity of newly marketed drugs. We noted ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The relation between low-dose radiation exposure and the development of myeloma remains in doubt. Available data are unconvincing, and the information provided by Drs. Najarian and Castleman¹ must be interpreted with caution in the absence ...

No extract is available for articles shorter than 400 words.

To the Editor: Crohn's disease is an inflammatory bowel disease of increasing incidence and unknown origin. Mononuclear-cell infiltration¹ of the lesions suggests that immunologic mechanisms may be involved. However, none of the various immunologic ...

To the Editor: There has recently been an increasing number of reports of hyperphenylalaninemia caused by inherited deficiencies of the enzymes needed to regenerate tetrahydrobiopterin.^{1 2 3} Tetrahydrobiopterin deficiency results in a relative diminution ...

To the Editor: Darsee et al. are to be congratulated on their excellent article¹ in the April 19 issue of the Journal. We would like to comment on several of their findings in terms of our experience with echocardiographic asymmetric septal hypertrophy ...

No extract is available for articles shorter than 400 words.

A black woman in Mississippi's Delta told me in 1969, as I went from home to home with other doctors trying to understand how it went for extremely poor and hard-pressed people:

We don't have it good here. It's no good at all. I turn and ask the Lord, a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

These two textbooks are as different as any in the same field can be. The manual is a short work intended as a practical guide to diagnostic studies and to the organization of a clinical imaging facility for newcomers to the field. The handbook is a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

With the publication of the first edition of this book in 1965, the editors and authors ushered in the development of a new field in clinical medicine supported by a burgeoning scientific data base. This book provided instant definition of a clinical ...

PROGRAMS FROM McGILL UNIVERSITY

McGill University Centre for Continuing Medical Education has made available a schedule of continuing-education programs for the academic year 1979–1980.

For more information write to the Secretary, Centre for Continuing ...

The President has explained that the Cabinet changes he made last month will help him transit from merely managing the government to leading the country, the implication being that he has mastered the first task and now must get on with the second.

The ...