HYPOGLYCEMIA caused by inborn errors of metabolism, including disturbances of organicacid metabolism,¹ usually appears during infancy or childhood. We have recently treated a 19-year-old woman who had episodic vomiting, severe hypoglycemia, and fatty ...

WHICH events should be counted in a randomized clinical trial, and when they are counted, which treatment should be blamed? That a controversy exists is clear from reading "Letters" columns after publication of randomized clinical trials^{1 2 3 4 5 6 7}; ...

Medical Technology — Center Stage in the Debate over Medical Costs

THOSE who deliver medical care to Americans are involved in a contentious debate with those who pay for much of that care. The argument revolves around the costs of modern medical ...

(Second of Two Parts)

Treatment

Management of the Primary Tumor

Although it is well known that a tumorous testis should be removed through an inguinal incision with complete excision of the spermatic cord, many patients have a transscrotal biopsy or ...

THE psychological impact of chemotherapy-induced alopecia represents one of the more devastating side effects of cancer chemotherapy and, in some instances, leads patients to refuse potentially curative chemotherapy. The problem of alopecia is severe when ...

THE proliferative capacity of human cells can be destroyed by ionizing radiation, and the rate of killing by radiation is 2.5 to three times higher in the presence of oxygen than under hypoxic conditions. Since solid tumors often have zones of necrosis ...

A NEW breakthrough has come in the legal development of patient's rights. The Massachusetts Legislature, one of the most cautious and slow-moving lawmaking bodies in the nation, has enacted a quite comprehensive Bill of Rights for patients. The law was ...

Presentation of Case

A 28-year-old woman was admitted to the hospital because of jaundice.

She was well until two months earlier, when an epigastric ache developed, with radiation to the back. Pain occurred three or four times daily, was unrelated to the ...

Sometimes a drug or other exogenous substance affects cellular enzymatic processes in such a way as to mimic, more or less precisely, the results of a gene mutation. Only a few examples come to mind, of which the most striking, if rather complex, ...

According to a recent report from the Health Care Financing Administration,¹ national expenditures for personal health care rose by about $110 billion between 1969 and 1978. Sixty-three per cent of that increase was due to the inflation of medical prices ...

It is Christmas Eve at the Journal. From the top of the Countway Library we look down on Shattuck Street, in daytime a bustling cul-de-sac, delivery alley, and parking lot, now dark and almost deserted. The staff has departed, and we remain in the quiet ...

The "glucoreceptor" hypothesis has evolved in large part from one of the few surviving generalizations about diabetes mellitus. Patients with this disorder do not respond appropriately to glucose signals. For example, those with hyperglycemia during ...

DEATHS

John — George Robert John, M.D., of Mattapoisett, died on February 19. He was in his 47th year.

Dr. John received his degree from Boston University School of Medicine in 1957. He served as city physician for New Bedford and was a member of the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

As I struggled to board the crowded shuttle to Boston at LaGuardia Airport recently, I overheard a well dressed 35-year-old woman lament to her equally sophisticated companion, "I'm ready to remarry. Unattachment is for the birds. I would welcome some ...

During the introspective 1970's, our patients became increasingly aware of how their own behavior could affect their health. Likewise, we physicians became increasingly aware of how their "compliant" behavior could affect our ability to improve their ...

The introduction characterizes this handbook as "a description of an approach, a listing of critical information, and an outline of some guidelines" for use by physicians, nurses, and students in the diagnosis, management, prevention, and control of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

PROGRAMS FROM THE UNIVERSITY OF CALIFORNIA

The University of California, San Diego, will present the following programs: "Nuclear Medicine," February 4–7; "Cardiopulmonary Imaging," February 8–10; "Ultrasonography Update," February 11–14; "Radiologic ...

Picking up where we left off here last month on the widespread pessimism about the condition and future of American science — when, in fact, optimism is in order — notice should be taken of the latest edition of what amounts to the official scorebook on ...