TWENTY-NINE years have passed since the introduction of corticosteroid treatment for the nephrotic syndrome.¹ Children with the "lipoidnephrosis" form of the syndrome usually have such a rapid and complete response to this therapy that its value seems ...

VON WILLEBRAND'S disease of the classic "autosomal-dominant" form is usually symptomatic in the heterozygous state. A less common but clinically more severe "recessive" form of the disorder is manifest when inherited from both parents. The heterozygous ...

IN the course of evaluating the long-term effectiveness of our drug-abuse treatment program, we discovered a sample of patients who had been initially admitted for inpatient treatment in 1972, and in whom a pattern of virtually continuous drug abuse since ...

AS the United States debates the causes of burgeoning health-care costs, much discussion is focused on containing the cost of hospitalization. Public attention has turned also to physicians' fees and income, partly because of the widely publicized study ...

(Second of Two Parts)

Modifications of Hemodialysis Therapy

Sequential Ultrafiltration and Dialysis

Patients on MH rely mainly on ultrafiltration to remove salt and water that accumulate despite insensible losses and residual urine output. During ...

ACUTE exposure to high altitude results in respiratory alkalosis. With time ("acclimatization") blood pH tends to return to normal levels¹; return is hastened by acetazolamide, a carbonic anhydrase inhibitor that slows the hydration of carbon dioxide and ...

Presentation of Case

A 54-year-old man was admitted to the hospital because of leukemia.

He was well until two years earlier, when he became fatigued and had occasional night sweats. Laboratory studies at another hospital showed that the hematocrit was 40 ...

Each year in this country, 8000 to 10,000 people enter the terminal stages of chronic renal disease. Most have some form of primary glomerulopathy, by which I mean idiopathic glomerular injury that is not part of a systemic disease. Early in the course of ...

The report by Mc Lellan et al. in this issue of the Journal raises intriguing questions about the relation between various forms of drug abuse and psychopathology and suggests some specific areas that the clinician might explore when obtaining a history ...

In a brief report in this issue, Sutton and his colleagues give us the results of further physiologic research done on the windswept high plateau of one of the largest mountain massifs in the world, Mount Logan (6050 m, 19,849 feet) in the Canadian Yukon.

No extract is available for articles shorter than 400 words.

To the Editor: We present here the case history of a patient in whom fever occurred as a side effect of therapy with clofibrate.

A 59-year-old woman presented with a temperature of 39°C and increasing chest pain of two days' duration. The patient has ...

No extract is available for articles shorter than 400 words.

To the Editor: We have had two cases similar to that of the patient with persistent aortic-outflow obstruction recently discussed in the Journal.* After uneventful insertion of a prosthetic aortic valve, pressure measurements in the left ventricle and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In the August 23 issue of the Journal, Descos et al. report that serum levels of β₂-microglobulin correlate with activity in Crohn's disease.¹ They consider follow-up studies to be necessary to determine whether elevations of serum levels ...

No extract is available for articles shorter than 400 words.

To the Editor: It has long been known that patients often wait a long time in a hospital outpatient department or physician's office before being seen by a doctor. This problem has existed for decades and has been the subject of formal studies for almost ...

To the Editor: In his article in the issue of June 14, Dr. Moore compares 1978 hospitalization rates of United Healthcare with rates of two other health-care plans also based in Seattle. He notes the large differences of rates among the plans and that ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In Great Britain, as in the United States, care for people with schizophrenia, retardation, dementia, or the other chronic mental disabilities is enmeshed in controversy and disarray. Although hospitals have been decried by proponents of ...

No extract is available for articles shorter than 400 words.

I go into it laughing and come out screaming, for it's been way too much of a good thing and far too much of a bad one. I mean, it's really complicated — a caligula for every augustus. Mania must make sense to someone, but I can't imagine how.

— Patient ...

Recognizing that most textbooks in neurology have limitations concerning up-to-date modes of therapy, the authors of this book offer a comprehensive, current approach to the treatment of neurologic disease. The book was written by members of the faculty ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.