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December 6, 1979  Vol. 301 No. 23

Original Articles
1245-1249

    SEVERE combined immune deficiency (SCID) is a heterogeneous and uniformly fatal disorder characterized by the failure of specific humoral and cellular immunity to develop.1 2 3 4 With rare exception,5 , 6 it presents with a marked impairment in the ...

    1249-1254

    STUDIES of the very old have suggested that good mental health may prolong good physical health.1 2 3 Recent review articles,4 , 5 have presented evidence of increased mortality (excluding accidents and suicide) among persons with poor mental health. The ...

    Special Article
    1254-1259

    THIS paper deals with the physician-investigator as an endangered species and with the future of clinical research. Clinical research includes the wide range of activities extending from epidemiology to studies of patients, to laboratory studies of ...

    Medical Progress
    1260-1265

    (First of Two Parts)

    IN the past two decades, maintenance hemodialysis (MH) for end-stage renal disease has evolved dramatically, from a tentative treatment for a small, carefully selected group of patients in Seattle,1 to a broadly applied therapy that ...

    Medical Intelligence
    1266-1270

    TWO agents that induce thrombolytic activity have recently been approved for clinical use by the Food and Drug Administration: streptokinase (marketed as Streptase by Hoechst-Roussel Pharmaceuticals, Somerville, NJ, and as Kabikinase by Kabi Group, ...

    1271-1273

    REVERSIBLE renal failure and nephrotic syndrome developed in three patients taking therapeutic doses of either fenoprofen or naproxen; both drugs are phenylalkanoic acids used as anti-inflammatory agents. We present here the clinical and pathological ...

    1273-1276

    STRATEGY for diagnosing renovascular hypertension has been influenced by an estimate that the disorder has a prevalence of 5 per cent or less in the population with hypertension.1 To apply that estimate to an individual patient with hypertension assumes ...

    Case Records of the Massachusetts General Hospital
    1276-1281

    Presentation of Case

    A 53-year-old truck driver was admitted to the hospital because of pain in the shoulder.

    The patient had diabetes of unknown duration, controlled by diet. He was well until the day of admission, when he went to another hospital ...

    Editorials
    1282-1283

    The article by George Vaillant in this issue presents evidence, derived from a longitudinal study of a selected sample of college men, that poor mental health is associated with deterioration in physical health, over and above the effects of substance ...

    1283-1285

      During the past decade, while government and the private sector have emphasized the need for primary-care physicians, another manpower problem of great importance has developed, almost unnoticed. There has been a clear decline in the number of physicians ...

      Sounding Board
      1285-1287

      In many teaching hospitals around the country, the medical resident's morning report, presented to the department chairman or to his delegate, is the intellectual highlight of the day. Work rounds have been completed, the problems of patients have been ...

      Correspondence
      1288

      To the Editor: Because of recent concern over the transmission of "slow-virus" diseases to surgical or autopsy personnel, recipients of corneal transplants, and patients undergoing brain studies with depth electrodes, we would like to remind readers of ...

      1288

      No extract is available for articles shorter than 400 words.

      1288-1289

      No extract is available for articles shorter than 400 words.

      1289

      No extract is available for articles shorter than 400 words.

      1289-1290

      No extract is available for articles shorter than 400 words.

      1290

      No extract is available for articles shorter than 400 words.

      1290

      No extract is available for articles shorter than 400 words.

      1291-1292

      To the Editor: Recent studies published in the Journal 1 , 2 indicate that hemochromatosis is an autosomal recessive condition with calculated homozygote frequencies (q2) ranging from one in 319 among Utah Mormons2 to one in 400 among Frenchmen (Brittany)...

      1292

      No extract is available for articles shorter than 400 words.

      1292-1293

      No extract is available for articles shorter than 400 words.

      1293

      No extract is available for articles shorter than 400 words.

      1293

      No extract is available for articles shorter than 400 words.

      1293-1294

      To the Editor: The correspondence on "Medspeak" in your August 30 issue, which continues the debate about the inability of doctors to communicate effectively, needs to be taken a few steps further if we are to attempt to solve the problem, rather than ...

      1294-1295

      No extract is available for articles shorter than 400 words.

      Occasional Notes
      1295-1296

      From June 5 to 7, 1979, I attended a conference entitled "Clinical Research: Elements for a prognosis" at the University of Chicago Center for Policy Study. Conferences on the relation between public policy and medical practice, pedagogy, or research are ...

      Book Reviews
      1297

      Many of the controversies among psychiatrists about the effects and role of electroconvulsive therapy (ECT) stem from the lack of a well-formulated education and training. The controversies have now affected public attitudes so that in some states it may ...

      1297-1298

      The medical community has recently awakened to the biologic and clinical importance of sleep, during which many normal and abnormal physiologic events transpire. Particular importance is attached to breathing or the lack of it, since respiratory ...

      1298

      The new edition of this popular textbook is similar in scope and content to previous editions. The author's aim is to provide a concise summary of human physiology that will be useful to medical students. For the most part, the book achieves this aim. The ...

      1298

      If you want information on national population planning or family-planning programs around the world, this book is a good place to start. The material is extensive, well documented, and current; much of it is summarized in tables and figures. One author ...

      1298-1299

      No extract is available for articles shorter than 400 words.

      Notices
      1299-1300

      HEALTH HAZARDS OF NUCLEAR TECHNOLOGY

      The Physicians for Social Responsibility will present a panel discussion highlighting the health hazards of nuclear technology on December 11 at 8 p.m. at the Harvard Science Center in Cambridge, Massachusetts.

      For ...

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