IN 1964, Dotter and Judkins¹ introduced the technic of transluminal angioplasty for the treatment of atherosclerotic obstruction of the femoral artery. Despite their enthusiasm, the technic has been largely ignored in the United States. In Europe, however,...

FLUDROCORTISONE, a synthetic mineralocorticoid, is used commonly in the treatment of chronic orthostatic hypotension. Although the drug may provide clinical benefits by increasing blood pressure in the standing position, it can produce hypertension in the ...

IN 1968, American medical schools made a concerted effort to remedy past inequities in the admission of students from minority groups or with economically disadvantaged backgrounds. Generally, this effort took three forms: increased financial aid, ...

(Second of Two Parts)

How Do Defects in Biosynthesis Explain Genetic Diseases of Collagen?

There are many rare genetic diseases that involve connective tissues, such as skin and bone.

As the information reviewed above about collagen structure and ...

THE relation between coronary-artery disease and marathon running is controversial. In 1961, the Journal published an article in which Currens and White discussed the autopsy findings on "Mr. Marathon"; the diameter of the coronary arteries was described ...

MOST prospective and retrospective epidemiologic studies show an inverse relation between physical activity and coronary-heart disease.^{1 2 3 4} In the most recently reported prospective study of Harvard alumni, in which leisure activity was assessed by ...

THE susceptibility of Neisseria gonorrhoeae to drying is well recognized and is a major factor in limiting the nonsexual transmission of this organism. However, Bailey and Scott have suggested that gonococci may survive for short periods in a moist ...

Presentation of Case

An 80-year-old woman was admitted to the hospital because of dyspnea.

She was well until three years earlier, when she began to have episodes of diplopia, dizziness and faintness when stooping or working in a hot environment. On one ...

DR. Andreas Grüntzig and his colleagues are to be congratulated. In this issue of the Journal, they report on their experience with their first 50 patients undergoing percutaneous transluminal coronary angioplasty. The report provides evidence that in ...

Two questions about long-distance running are addressed in this issue of the Journal: If people who go in for protracted, strenuous exercise have healthier cardiovascular systems, is the exercise itself responsible or are other factors, such as a ...

To the Editor: The work of Kelley and Baker, first reported in 1960,¹ established the efficacy and safety of progestational agents in the treatment of advanced endometrial carcinoma and has been the basis for hormonal therapy of the disease. Clearly, ...

To the Editor: Both in informal conversations and on the pages of journals such as this¹ a discussion is taking place over the potential value of interferon in clinical practice and the relative merits of the various preparations available. During this ...

To the Editor: The letter by Newman et al.¹ in the November 9, 1978, issue of the Journal describes encouraging results obtained with intraventricular monitoring of cerebrospinal-fluid pressure and intermittent intravenous mannitol at doses of 2 g per ...

To the Editor: The letter from Greentree, "Dangers of Vitamin B₆ in Nursing Mothers," in the January 18 issue of the Journal requires comment. He claims that there is solid evidence that pyridoxine inhibits the secretion of breast milk in the nursing ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A recent Sounding Board¹ provides a discussion and interpretation of P.L. 95–623, which established the National Center for Health Care Technology. Although the authors acknowledge that the concept underlying this legislation is sound, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Where should medical history orbit in the expanding universe of medical knowledge? How far out should it lie, for the curriculum, the library, the medical journals or for our collective self-image and political understanding?

Wherever in the universe ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Medicine

Cardiovascular

Advances ...

STUDY ON THE ENDOSCOPE

ECRI will conduct a study of the characteristics of endoscopes and endoscopical accessories and the hazards and risks associated with their use. Information is requested on problems with any endoscope or accessory. Forward ...

No extract is available for articles shorter than 400 words.