SEVERAL adverse hematologic effects have been associated with the use of drugs.^{1 2 3} Some drugs have direct toxic effects on the marrow,¹ and others exert their effect indirectly through immunologic mechanisms.² Drugs in the latter category can lead to ...

MYASTHENIA gravis is a specific autoimmune disease affecting nicotinic acetylcholine receptors of the neuromuscular junction and resulting in weakness and muscle fatigue.¹ In approximately 90 per cent of adult patients with this disease, serum IgG ...

NEARLY 30 years ago, Dean Willard Sperry of the Harvard Divinity School published a small book entitled The Ethical Basis of Medical Practice. It turned out to be a landmark of sorts, and the reason is contained in an offhand comment that appears half-way ...

BY selecting me as your 170th speaker, the Councilors of the Massachusetts Medical Society have accorded me a great honor, for which I am deeply appreciative. This custom of an Annual Discourse or Oration was inaugurated 175 years ago and has been a ...

(Second of Two Parts)

Immunologic Functions of the Pulmonary-Alveolar Macrophage (PAM)

The PAM functions importantly in pulmonary defense by participating in specific immunologic reactions and by interacting with other components of the immune system. The ...

FEW controversies in the practice of medicine have generated as much discussion as has the role of estrogen-replacement therapy in the climacteric woman. The literature is replete with articles about the potentially beneficial effects of estrogen ...

INFORMED consent has been examined in a number of recent "LawMedicine Notes"^{1 2 3} and in a commentary on randomized trials.⁴ These discussions have assumed that informed consent is required to protect the autonomy of human beings in making decisions about ...

Presentation of Case

A 22-year-old man was admitted to the hospital because of a question of drug ingestion.

He was reported to be a frequent abuser of illicit drugs, which included phencyclidine, lysergic acid and methaqualone, but there was no history ...

Diseases that result from immunologic destruction of mature, fully differentiated blood cells are familiar to most of us. Idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia and certain acquired neutropenias have long been recognized as ...

Ever since 1895, when D. D. Palmer, erstwhile "magnetic healer" and founder of the chiropractic movement, claimed to have restored a deaf janitor's hearing by manipulation of his spine, organized medicine has considered chiropractic a form of quackery and ...

Deaths

Maynard — Guy Burnham Maynard, Jr., M.D., formerly of Lexington, died on December 14, 1976. He was in his 62d year.

Dr. Maynard received his degree from Cornell University Medical School in 1943. He was a member of the American College of Surgeons ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We read with interest the article by Harmon and his colleagues¹ in the May 24 issue of the Journal describing renal failure in children treated with methyl CCNU. We describe below a patient in whom renal failure developed after prolonged ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Recent work has implicated autoaggression of the immune system toward pancreatic islet cells as a mechanism responsible for the pathogenesis of insulinopenic diabetes. Buschard et al.* appeared to have confirmed this notion by reporting ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The medical story of Raoul Dufy represents one of those rare instances in which a medical advance is made at exactly the right time to salvage creative functioning in an important person and thereby enrich our heritage. For this and many other reasons we ...

The Body in Question at first strikes one as the title of a nice English mystery, in the tradition of Dorothy Sayers or Agatha Christie. And it is a mystery and of English origin. But its approach to the body is scientific, and its aim is to examine ...

The physician caring for patients with pancreatitis is plagued by the lack of solid information. The pathogenesis and natural history of the disease are not known. Properly conducted therapeutic trials either have demonstrated the ineffectiveness of a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This one-volume review of urology is designed to "fill the gap between the unsophisticated introductory text and the excessively detailed treatise." Presumably, therefore, it would appeal to the reader whose needs and knowledge fall between those of the ...

No extract is available for articles shorter than 400 words.

Not many years ago, good books on renal function and renal disease were in short supply. Over the past several years this problem has been abundantly rectified. It seems likely that before the next decade is out every leading renal group in the English-...

COMPUTERS IN PRIVATE PRACTICE

The University of Health Sciences at the Chicago Medical School will present a program entitled "Choosing and Using a Computer in a Private Medical Practice" on October 26 and 27 in Chicago. The deadline for registration is ...