THIS study was initiated in late 1971 when saphenous-vein bypass for coronary heart disease was becoming widely accepted and used. Prospective, randomized studies are generally considered the most discriminating technic for evaluating new modes of therapy,...

THE last decade has witnessed a definite advance and new departure in medical genetics: prenatal diagnosis of genetic defects to determine whether a fetus believed to be at risk for some genetic disease actually has that disorder. Previously, genetic ...

THE association of chronic mucocutaneous candidiasis with hypofunction of one or more endocrine organs is referred to as the syndrome of candidiasis endocrinopathy. A case reported in 1929¹ featured candidiasis and hypoparathyroidism, which, together with ...

MEDICINE'S ability to collect information about the fetus has increased dramatically in the last few years. A variety of technics — collectively known as prenatal diagnosis — have made it possible to learn much about a fetus's genetic and metabolic state, ...

(Second of Two Parts)

Inter-relation between Thyroid Hormone, Catecholamines and β-Adrenergic Receptors

Previous speculation and many data in this area are omitted for the sake of brevity. Some of the manifestations of clinical thyrotoxicosis resemble ...

CHRONIC granulomatous disease of childhood is a disorder characterized by chronic recurrent infections beginning in the first year of life and resulting in death by the age of seven in one third of affected patients.¹ The disease results from a functional ...

PHYSICIANS in Britain can still practice without too much fear of litigation, and the number of serious complaints made against doctors and hospitals is surprisingly small. Indeed, it is sometimes thought that too little is done to safeguard standards of ...

Presentation of Case

A 64-year-old woman was admitted to the hospital because of splenomegaly.

She was well until six weeks earlier, when fever developed, accompanied by a dry cough and pleuritic pain in the left lower portion of the chest. A physician ...

Norris and his colleagues recently described protective effects of propranolol among patients with threatened myocardial infarction.¹ Their report highlights the remarkably rapid evolution of recent thinking concerning protection of ischemic myocardium ...

American medical care is considered the best and the most expensive in the world. We physicians are trained to be thorough. We believe that to be thorough we have to be complete. We are uneasy unless every possibility has been ruled out. I have been ...

This communication is being started as I await a flight to New Orleans, where I am to give Medical Grand Rounds at the LSU Medical School later today. The expenses for my trip and an honorarium of $500 are being provided by the USV Pharmaceutical Company. ...

To the Editor: We read with interest a recent letter to the Journal from Jope et al.¹ reporting that choline accumulates in erythrocytes of patients treated with lithium. Earlier studies had demonstrated a reduced influx of choline into red blood cells ...

To the Editor: In the article, "Coronary-Artery Spasm" in the September 28, 1978, issue of the Journal, Hillis and Braunwald emphasized the evidence implicating coronary vasospasm not only as the principal cause of Prinzmetal's variant angina but also as ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Recent studies by Duke University on acute myocardial infarction^{1 , 2} suggest that enormous costs may be saved through early discharge of patients with uncomplicated infarction. We have just completed a similar study in Honolulu to ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Recent reports^{1 , 2} have focused attention on the potential threat of drug-resistant pneumococci and on the need for immunization of patients at high risk of serious pneumococcal infection. In the United States, where multiply resistant ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The various forms of congenital adrenal hyperplasia are caused by different enzymatic deficiencies, each responsible for a given step in the biosynthesis of cortisol or aldosterone (or both). The most frequent forms of this disorder result ...

Cross-sectional anatomy was once the special preserve of the gross anatomist, a means of depicting visceral relations that were ultimately of greatest importance and value to the surgeon. Over two decades ago, transaxial tomography was introduced, and ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy and Histology

Aspiration ...

SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL

Seminars in Medicine of the Beth Israel Hospital will be held in the George Sherman Auditorium, Beth Israel Hospital, Boston, on the following Tuesdays at 4 p.m.

CONGRESS AND SYMPOSIUM ON ANDROLOGY

The ...

Stay in Washington long enough, and you'll see cycles of health-policy "reformers" arrive full of bright ideas and high hopes. And then, a few years later, many of them depart, and when they do, they almost invariably express despair about — as it's often ...