MORE than 80 per cent of lymphoid malignancies involve clonal proliferation of cells of the B-lymphocyte class.^{1 , 2} These cells synthesize and bear immunoglobulin on their surface membranes. Several studies have shown that surface immunoglobulin is a ...

GASTRIC autoimmunity has been studied for 20 years, and the "primary" autoimmune nature of addisonian (pernicious) anemia is now well established. Antibodies to gastric parietal cells or intrinsic factor (or both) are found in 90 per cent of patients with ...

BEFORE endoscopy was available, bleeding of the upper gastrointestinal tract was managed in an empiric manner. Patients whose bleeding could not be controlled medically were subjected to operation either without a preoperative diagnosis or with only a ...

OVER the past decade the need for increasing physician manpower has been repeatedly emphasized by the public sector. The Health Education Professional Assistance Act (PL 94–494) has reinforced the need to increase the number of American physicians by ...

UNTIL successful medical management of scleroderma crisis was reported,^{1 2 3 4} bilateral nephrectomy was thought to be the only therapy to control this emergency and permit survival.^{5 6 7} We report here two cases of dramatic reversal of scleroderma ...

IN the process of conducting studies to characterize the effects of age on bone mass and the skeleton in adult human subjects, we measured serum immunoreactive parathyroid hormone by a radioimmunoassay that is specific for the biologically inactive ...

THE plasma undetermined anion concentration (anion gap) is widely recognized as a valuable clinical tool.^{1 , 2} Although conventionally estimated as the difference between [Na⁺] or [Na⁺ + K⁺], on one hand, and [Cl– + HCO–₃], on the other, the anion gap is, ...

THE placebo effect is a component of any therapeutic intervention, and its influence is seen in many diseases.^{1 2 3 4 5} The symptoms of angina pectoris, in particular, are responsive to the placebo effect. Many of the treatments used since Heberden's⁶ ...

Presentation of Case

A 91-year-old woman was admitted to the hospital because of a mass in the right upper quadrant of the abdomen.

The patient was born in Italy and immigrated to this country at the age of 16 years. At 21 years a spontaneous abortion ...

The observation of small or moderate numbers of monoclonal B cells in the blood of patients with diffuse or even nodular B lymphomas is not particularly surprising; nevertheless, the sophisticated and convincing technics used by Ault in this issue of the ...

Atrophic gastritis consists of chronic inflammation and atrophy of the gastric mucosa. As the atrophy of gastric glands progresses, particularly in pernicious anemia, a heavy cellular infiltrate of lymphocytes and plasma cells persists.¹

The ...

The introduction of flexible fiberoptic endoscopes into clinical practice in 1961 vastly altered the traditional approach to gastrointestinal bleeding. Technical improvements in endoscopic instrumentation soon permitted effective viewing of the entire ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: One of the most common metabolic diseases,α₁-antitrypsin deficiency, is associated mainly with cirrhosis in children and with chronic obstructive lung disease in adults.^{1 2 3} This antitrypsin is the major protease inhibitor (Pi) of human ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

CONGRESS ON MEDICAL LAW

The fifth World Congress on Medical Law will be held at the University of Ghent, August 19–23.

For more information write to the Fifth World Congress on Medical Law, General Secretariat, Apotheekstraat 5, B-9000, Ghent, Belgium.

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