CRUSH syndrome is the systemic manifestation of muscle necrosis and consists of myoglobinuric renal failure, shock, acidosis and hyperkalemia. Since the description by Bywaters and Beall in 1941,¹ numerous articles have linked limb compression, muscle-...

THE pathogeneses and causes of juvenile-onset diabetes mellitus and maturity-onset diabetes are thought to differ. Juvenile-onset diabetes generally occurs in a younger age group; the onset is more abrupt, and a seasonal incidence has been reported.¹ In ...

RECURRENT herpes simplex labialis is thought to affect between 20 and 45 per cent of the United States' population, and almost 25 per cent of those afflicted will have recurrences that are frequent or severe or both.¹ Many forms of therapy have been tried,...

IT is widely believed that anything done in the public interest is good for society and good for the individual members of society. When the "anything" involves the health of the people, the belief is rapidly converted to doctrine. Doctrine nowadays means ...

ACUTE myelogenous leukemia is a neoplastic disease characterized by the proliferation of myeloblasts and other immature cells of the granulocytic series. Because of the common origin of several hematopoietic cell lines, abnormalities of proliferation or ...

METHYL CCNU (1- [2-chloroethyl] -3-[4-methyl cyclohexylj-1-nitrosourea) has been used to treat a variety of solid tumors^{1 2 3} for more than six years.⁴ It has been shown to be effective and to have an acceptable acute toxicity — mild gastrointestinal ...

Presentation of Case

A 17-year-old boy was admitted to the hospital because of a heart murmur.

He was born the sixth of nine children, of a normal delivery. His early growth and development were normal. At the age of five years a routine examination at ...

The compartmental syndrome is a condition in which increased pressure within an anatomic space compromises the circulation and function of the contents.¹ The two prerequisites for this syndrome are an envelope of limited compliance (such as fascia, skin, ...

It has long been known that insulin-deficiency diabetes mellitus (IDDM) results from an inflammatory process of the islet tissue of the pancreas (insulitis), leading to essentially complete destruction of the insulin-producing beta cells. The factors ...

When the term "overutilization" is applied to x-rays, its meaning should be defined. The definition that I shall employ is straightforward: "over-utilization" means excessive irradiation per unit of diagnostic information, therapeutic impact or health ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The report in which Dr. Russo¹ describes management of theophylline-induced seizures raises a broader issue about why toxicity with this drug continues to occur at major medical centers when the pharmacodynamics, pharmacokinetics and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Hypertension may occur in the necrotizing vasculitis associated with drug abuse,^{1 , 2} but the mechanism remains undefined. We report here a fatal case of hepatitis B in which hypertension was shown to be angiotensin dependent.

A 23-year-...

To the Editor: Extramedullary solitary plasmacytoma is a rare disease, confined mostly to upper respiratory passages, gastrointestinal tract and lymph nodes^{1 , 2} despite the wide distribution of plasma cells. We report an unusual case of solitary ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In his letter to the Editor in the February 15 issue of the Journal, Berkson¹ advocates thioctic acid in treatment of hepatotoxic mushroom (Amanita phalloides) poisoning. Although thioctic acid may be helpful in the management of acute A. ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

At the outset, the editors express their intention that this new edition of an old and honored pediatric text continue the "basic purpose as a working manual of pediatrics." The new title is used "to reflect our wider concept of the pediatrician's role in ...

Salmon states that his book is "primarily intended as a reference work and the numerous illustrations have been selected to show the characteristic details of as many syndromes as possible." Overall, he has achieved this objective.

The study of symptom ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Considering that relatively few textbooks about glaucoma are available, this book is welcome. Glaucoma is a common disease: 0.3 to 0.7 per cent of Americans over the age of 60 years have damage to the optic nerve with associated field loss, and another 2 ...

No extract is available for articles shorter than 400 words.

COURSE IN EMERGENCY MEDICINE

Doctor's Essential Services, the Providence Hospital of Oakland, and Emergency Physicians of San Leandro will present a seminar in emergency medicine, June 6–10 at the Stanford Sierra Lodge in Lake Tahoe, California.

Further ...

The political doctors attending the biomedical research enterprise agree that much is wrong and that something should be done, but though all profess affection and concern for the object of their attention, their diagnoses and remedies differ on many ...