CHOLESTEROL gallstones are uncommon in childhood, but the prevalence of the disorder rises after puberty, with women showing a higher prevalence than men.^{1 2 3 4 5 6 7 8} To elucidate the basis of the postpubertal rise in cholesterol cholelithiasis and of ...

HYPERTROPHIC cardiomyopathy (also known as idiopathic hypertrophic subaortic stenosis and asymmetric septal hypertrophy) is a common disorder of cardiac muscle characterized by asymmetric septal hypertrophy, systolic anterior motion of the mitral valve (...

ALTHOUGH anorexia nervosa has been recognized for nearly three centuries,¹ the cause and pathophysiology of the disease remain obscure. It affects primarily young females with weight loss and abnormal ideation regarding food and body image. The disease is ...

SERRATIA MARCESCENS is a bacterium recognized with increasing frequency as a cause of serious infection in man. This micro-organism has a romantic history dating to antiquity, when, because of production of a red pigment, it masqueraded as blood. In this ...

FOR more than a quarter of a century, a wealth of epidemiologic evidence has causatively linked tobacco smoking with lung cancer.^{1 2 3 4 5} Decades ago, smoking was shown to increase the risk of premature heart attack and was recognized as a major factor ...

THE pathogenesis of lymphomas in man is unknown. A variety of factors are associated with lymphoma induction in animals, including immuno-suppression, immune stimulation, autoimmunity, loss of suppressor T-lymphocyte function, retravirus infection, drugs ...

ORGANIC psychosyndromes, paralysis of gaze, nystagmus and myoclonus may dominate the clinical appearance of Whipple's disease.^{1 2 3} The basis for these signs is infiltration of the cerebral gray matter by sickle-particle-containing (SPC) cells, as ...

Presentation of Case

A 61-year-old man was admitted to the hospital because of bleeding per rectum.

Seven years earlier chronic diarrhea developed, associated with dull pain in the left lower quadrant of the abdomen. Four years before admission he entered ...

Gallstones consisting principally of cholesterol are common in Western industrialized and "developed" nations. On the other hand, cholesterol stones have been uncommon to rare in many Asian and African peoples¹ (who do, however, have calcium bilirubinate ...

It has become an axiom of medical genetics that most genetic diseases are etiologically heterogeneous. Thus, similarly appearing diseases may have different genetic as well as nongenetic causes. The combination of clinical, pathophysiologic, biochemical ...

Whipple's disease is usually considered an intestinal disorder characterized by malabsorption and macrophages that stain with periodic acidSchiff (PAS). In fact, this disease is a chronic, multisystem, antibiotic-responsive bacterial infection that may ...

No extract is available for articles shorter than 400 words.

To the Editor: The report by Antunes et al. in the January 4 issue of the Journal has much to commend it but contributes little more than is already known — i.e., estrogens have a role in the genesis of endometrial cancer. Such lesions are rare in women ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We read with great interest the paper by Drs. Schussler, Schaffner and Korn on serum thyroid hormone binding in patients with chronic active liver disease in the September 7, 1978, issue of the Journal, and we are grateful for their ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In his Law-Medicine Note in the January 4 issue of the Journal, Professor Curran reviewed the recently published survey of medical-malpractice claims filed with the St. Paul Fire and Marine Insurance Company from October, 1973, through ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

In 1978, the University of Pennsylvania held a symposium in honor of Isaac Starr. The university managed the affair with the poise and dignity characteristic of an honorable and distinguished institution. In events honoring great men, whether they are ...

No extract is available for articles shorter than 400 words.

Dr. Taber has rightly addressed the need to provide specialty information to heterogeneous caretakers in emergency settings: family practitioners, moonlighting residents from a variety of services and triage nurses. He has chosen a problem-oriented ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Once the only available sources of information, classic medical textbooks of yore have, in the main, been succeeded by a spate of monographs and other hard-covered tracts that offer the advantage of currentness. Nevertheless, for ready reference in one's ...

No extract is available for articles shorter than 400 words.

This book attempts to answer several questions: What is the unique pathology presented in advanced age? What is the target population of geriatric practice? And why should this practice have a special place within the field of internal medicine?

Cape ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy and Histology

Atlas of ...

COURSES FROM WASHINGTON UNIVERSITY

Washington University School of Medicine will present the following programs: "Symposium on Obstetrics and Gynecology," April 26 and 27; "Diabetes Mellitus Update," May 3 and 4; "Neuromuscular Diseases," May 10–12; "...

No extract is available for articles shorter than 400 words.