THE neurotoxic properties of lead at high dose are well known and not a subject of general controversy.^{1 , 2} A source of considerable debate, however, is whether or not blood lead levels below those associated with obvious symptoms have adverse effects on ...

BOTH infection and disease are well documented for persons who have consumed toxoplasma in raw or inadequately cooked meat.^{1 , 2} More recently, the role of cats shedding toxoplasma oocysts as a source of human and animal infection has been widely ...

ATAXIA telangiectasia is a genetically transmitted disorder characterized by progressive neurologic dysfunction, superficial telangiectasia and abnormalities of cellular and humoral immunity.^{1 2 3} Patients have a predisposition to development of cancers, ...

(Second of Three Parts)

Colon, Rectum and Anus

Polypoid Disease

Watne et al. studied 126 patients with Gardner's syndrome. Sixty per cent of the patients had soft-tissue tumors, 32 per cent osteomas, 67 per cent polyposis, and 20 per cent the entire ...

DRUGS that increase blood flow by direct or indirect action on the peripheral blood vessels are termed "vasodilators." These agents are widely advertised in medical journals and consume a substantial percentage of the drug dollar in this country.¹ ...

IT is common for a patient to perceive his heartbeat by hearing cardiac sounds when the side of his head is placed on a pillow at night.¹ Indeed, most physicians are familiar with complaints of precordial "thumping" or "pounding" when a subject reclines ...

IT has been suggested that aplastic anemia may be due to either a deficiency of hematopoietic stem cells or an adverse interaction between stem cells and factors in the marrow microenvironment.¹ The possibility that autoreactive antibodies are involved in ...

IN an important first-impression decision, the Federal District Court in Tennessee has upheld the authority of the University of Tennessee to dismiss full-time tenured professors at the Medical School who had not agreed to and signed an income-limitation ...

Presentation of Case

A 52-year-old man was admitted to the hospital because of a pulmonary nodule.

There was a history of asthma for 20 years, with positive skin tests to oak, birch and house-dust antigens, as well as to dog dander. The patient kept two ...

"Bob," asked the editor of the Journal, "What preposition do I use, 'the hope of success is small,' or 'the hope for success is small'?"

"Bob," the editor said on another occasion, "What do you think of this submission? (a piece of serious verse usually ...

Lead, a useful but toxic metal, occurs naturally in the ecosystem. It has been mined and processed for many centuries, but its dispersion in the human environment rose sharply only after industrialization. Studies of the lead concentrations of chronologic ...

T. S. Eliot¹ once wrote of the subscribers to another Boston publication:

The readers of the Boston Evening Transcript Sway in the wind like a field of ripe corn When evening quickens faintly in the street, Wakening the appetites of life in some And to ...

Two recent issues of the Journal ^{1 , 2} contain indignant letters protesting the publicity last November that attended the introduction of sulindac, a "new" anti-arthritic drug approved for release by the FDA and now marketed in this country by Merck Sharp ...

No extract is available for articles shorter than 400 words.

To the Editor: I wish to report the case of an 18-year-old woman in whom juvenile rheumatoid arthritis developed at the age of 12 years; she was treated with salicylates and intermittent low-dose steroids. Because of a mild elevation in serum aspartate ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: An outbred colony of non-obese Wistar rats (BB) with a high rate of spontaneous, apparently genetically determined diabetes mellitus has recently been described.^{1 , 2} The diabetes develops suddenly at two to four months of age with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The Sounding Board, entitled "Changing Diagnosis Codes," in the November 23, 1978, issue of the Journal, creates the misguided impression that problems in implementing Clinical Modification of the ninth edition of the International ...

To the Editor: In a recent Sounding Board view of manpower policy, Drs. Samuel O. Thier and Robert W. Berliner correctly defined the problem of physician-manpower-policy development in the United States.¹ Manpower policy has been based mainly on opinion ...

In 1753, James Lind, Physician to the Naval Hospital in Portsmouth, England, presented his Treatise of the Scurvy. Others had offered similar but less well documented information, but it was Lind who amassed the most persuasive evidence that lemon juice ...

Despite the somber nature of this book's subject, it is — paradoxically — enjoyable to read. The answer to this paradox is found in the human, personal style of the whole book: almost every chapter imparts knowledge, information and experience gained from ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy and Histology

Histology ...

SYMPOSIUMS ON DIETHYLSTILBESTROL

The Brookline Unit of the American Cancer Society and the Boston Hospital for Women will present a DES symposium for medical personnel on April 7 (from 8:30 till noon) at the Lying-In Auditorium of the Boston Hospital for ...

No extract is available for articles shorter than 400 words.