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Table of contents for

January 4, 1979  Vol. 300 No. 1

Original Articles
1-5

    RECENTLY, Hollis et al. described the laboratory characteristics of an as yet unnamed halophilic Vibrio species.1 This Vibrio has been shown by deoxyribonucleic acid reassociation experiments to be a single species distinct from two other halophilic ...

    5-8

      HOMOZYGOUS β-thalassemia is an inherited red-cell disorder characterized by severe anemia beginning at a few months of age, bone-marrow hyperplasia and a typical hemoglobin electrophoresis with markedly decreased or absent hemoglobin A and elevations of ...

      9-13

      A NUMBER of case–control (retrospective) studies have reported an association between use of estrogens in the menopause and subsequent development of cancer of the uterine corpus.1 2 3 4 5 Despite different types of controls and dissimilar methods of ...

      14-17

        DURING starvation, the body draws upon its fat stores to meet energy requirements and upon muscle protein for both gluconeogenesis and labile protein reserves. A decrease in metabolic rate and adaptation of the central nervous system to the oxidation of ...

        Medical Intelligence
        17-22

          Dobutamine* is a new, synthetic, intravenously administered catecholamine that acts directly to increase myocardial contractility without inducing marked tachycardia or greatly changing peripheral arterial resistance.1 These features make it useful for ...

          22-24

            THE patients who sign out of general hospitals against advice have received little attention in the medical literature. A survey of the problem in our hospital in 1974 revealed the incidence of such discharges to be 0.7 per cent and found evidence of ...

            24-26

            THEOPHYLLINE toxicity causing neurologic and cardiac manifestations is usually associated with high serum concentrations.1 , 2 Supportive care is the mainstay after the drug is discontinued. Nevertheless, there are patients in whom generalized seizures, ...

            26-27

            SINCE the malpractice-insurance crisis of 1975, it has generally been reported that medical malpractice claims have quieted down somewhat. Data to support this impression have been lacking, however. Continued high monetary inflation in the United States ...

            Case Records of the Massachusetts General Hospital
            28-37

            Presentation of Case

            A 76-year-old woman was admitted to the hospital because of chest pain.

            There was a history of sarcoidosis, diagnosed by biopsy 16 years earlier, with cervical and hilar lymphadenopathy, hepatomegaly, splenomegaly and pancytopenia; ...

            Editorials
            38-39

              Today, we publish the first number of Volume 300, a fact that should not go unnoticed. But the event has more numerical than historical importance, and it calls for explanation rather than celebration.

              We publish two volumes annually, so one might at ...

              39-41

                The Center for Disease Control, with its uniquely trained cadre of physician epidemiologists and microbiologists, continues, by its painstaking detective work, to delineate new and treatable communicable diseases. The past few years, for example, have ...

                41-42

                It is now nearly 50 years since the metabolic response to injury was described by Sir David Cuthbertson,1 who happily still studies this interesting phenomenon. During the intervening half-century, including a World War and a progressive increase in ...

                42-43

                The present availability of limited quantities of human leukocyte interferon has allowed preliminary clinical investigation which has demonstrated some useful effects in diseases ranging from the common cold to cancer. Interferon is a naturally produced ...

                Correspondence
                44

                No extract is available for articles shorter than 400 words.

                44-45

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                45

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                45

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                45-46

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                46

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                46-47

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                47

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                47

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                48

                No extract is available for articles shorter than 400 words.

                48

                To the Editor: The article and comments by McKenna and Wacker1 were indeed very interesting and pinpoint a number of crucial questions. The first of these questions is the definition of a "family doctor." The second is whether the choice of medical-care ...

                48-49

                No extract is available for articles shorter than 400 words.

                49-50

                No extract is available for articles shorter than 400 words.

                50

                To the Editor: In the October 19, 1978, issue of the Journal the following classified advertisement appeared: "Wanted: Board Certified Doctors with extensive expertise in their field to evaluate and testify in medical malpractice cases for existing ...

                Notices
                50-51

                SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL

                Seminars in Medicine of the Beth Israel Hospital will be held in the George Sherman Auditorium, Beth Israel Hospital, Boston on the following Tuesdays at 4 p.m.

                REVIEW FOR CERTIFICATION IN INTERNAL MEDICINE

                ...
                Information for Authors
                52

                Manuscripts

                Manuscripts containing original material (Original Articles, Special Articles and brief reports in Medical Intelligence) are accepted for consideration with the understanding that neither the article, nor any part of its essential substance, ...

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