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Table of contents for

August 24, 1978  Vol. 299 No. 8

Original Articles
369-374

IT is commonly assumed that a patient who has rejected a kidney transplant is different from a patient who has never received a transplant by being "immunized" in the course of rejecting the first graft. This widespread assumption is an extrapolation from ...

375-380

INSULIN-dependent diabetes mellitus in children and adolescents is characterized by a dramatic decrease in glucose-induced insulin secretion and a progressive loss of endogenous insulin production that is concomitant with a disappearance of beta cells ...

381-385

THE effect of oral contraceptive use on the development of mammary cancer remains a subject of controversy.1 , 2 At present, little evidence exists that the "pill" either increases or decreases the risk of breast cancer3 4 5 6 7 although in one study an ...

Special Article
386-392

THE financing of treatment of renal disease is a matter of much current debate as both Congress and health-care providers re-evaluate the successes and failures of PL 92–603, the law that has provided Medicare coverage since July, 1973, for patients ...

Medical Progress
393-401

    (Second of Two Parts)

    Brain Death as Extensive Brain Necrosis

    The studies quoted in the first part of this review used as their basic concept of brain death a state of irreversible brain damage that preceded inevitable cardiac arrest. They therefore tried ...

    Case Records of the Massachusetts General Hospital
    401-409

    Presentation of Case

    A 63-year-old woman was admitted to the hospital because of diarrhea.

    There was a long history of degenerative arthritis of the left hip. Two years before admission pain became so severe that the patient was unable to walk and began a ...

    Editorials
    410-412

      The inescapable logic of the concept that death of the brain is equivalent to death of the person has now achieved widespread acceptance. In the decade since a Harvard Ad Hoc Committee enunciated the view and gave specific guidelines for making such a ...

      412-413

        Central in the constellation of anatomic and physiologic abnormalities that make up the syndrome of diabetes mellitus in man is an absolute or relative deficiency in pancreatic beta-cell function. For over 100 years anatomists have studied the histology ...

        Sounding Board
        413-415

        There is much about the Drug Regulation Reform Act of 1978 that can be improved, but I will confine my comments to the disincentives that it would create for the research and development of new drugs in this country. I don't think anybody questions that ...

        Massachusetts Department of Public Health
        415-418

        The morbid and mortal harm of strokes may be reduced by public-health programs addressed to the underlying risk factors — particularly the early diagnosis and control of hypertension — as well as by medical management of the condition. The benefits of ...

        Correspondence
        419-421

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        422-423

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        423-424

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        424

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        424

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        424

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        424-425

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        425

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        425-426

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        426

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        426-427

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        427

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        Book Reviews
        427

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        427-428

        The proper management of the patient with gastrointestinal bleeding involves a series of important decisions, each based on the accurate clinical assessment of the problem at hand. Many of these steps are based on sound physiologic or epidemiologic ...

        428

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        428

        The textbook definition of a textbook describes a volume containing the basic principles of a subject on which a course of instruction can be based. As such, this large multiauthored textbook of adverse drug reactions in many ways achieves this ambitious ...

        429

        This is a remarkable although somewhat idiosyncratic book. The author, as he states in his preface, has attempted to bridge the gap between the hematology of conventional blood smears and the cell biology of today. The purpose is to encourage the ...

        Notices
        429-430

        PROGRAMS FROM THE STATE UNIVERSITY OF NEW YORK

        The State University of New York at Buffalo will present the following programs: "Obstetric Anesthesiology and Perinatology," September 15 and 16; and "Electrocardiography: the Diagnosis of Chamber Overloads ...

        Correction
        430

        No extract is available for articles shorter than 400 words.

        Washington Report
        431-432

        After the well publicized falling-out late in July between President Carter and Senator Kennedy on national health insurance, I asked a White House staff member who is closely concerned with the subject to speculate on the outcome of this latest chapter ...

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