THE treatment of patients with chronic end-stage renal disease by kidney transplantation originated in the 1950's, and by hemodialysis in the 1960's. In 1962, the modern era of clinical transplantation began with the first successful use of chemical ...

ACCELERATED atherosclerosis is a frequent complication in patients on chronic hemodialysis, and the major cause of death among these patients is atherosclerotic cardiovascular disease.¹ Considerable attention has been paid to the factors involved in this ...

BREAST cancers frequently manifest a spectrum of heterogeneous biologic behaviors even within a single histologic type. By measuring the tumor estrogen-receptor content, one can now separate breast cancers into at least two biologically distinct groups: ...

(Second of Two Parts)

Suppressor Cells in the Enhancement of Tumor Growth

Oncogenesis is accompanied by the appearance of tumor-associated cellular neoantigens in a large number of carefully studied models. The immuno-competent cells of the host can ...

THE neuropharmacologic properties of the many benzodiazepine derivatives available for clinical use are qualitatively similar if not identical.^{1 , 2} Nonetheless, new benzodiazepines continue to be marketed and promoted as "unique" agents for the treatment ...

DURING the past two decades substantial progress has been made in the treatment of pediatric solid tumors. Improved survival is accounted for by a better understanding of the natural history of the various tumors, improved histologic classifications, new ...

ONE of the most important experiments in medical-care regulation of this country in the 1970's is the group of organizations called PSRO's, or Professional Standards Review Organizations. These organizations were designed by the United States Congress to ...

Presentation of Case

A 66-year-old right-handed woman was admitted to the hospital because of abulia, paraparesis and blindness in the left eye.

She was well until 4 1/2 years earlier, when a generalized convulsive seizure occurred. Neurologic evaluation ...

The results of the largest and longest clinical trial of the effects on the incidence of coronary heart disease of reducing elevated plasma cholesterol concentrations in apparently normal men are now available.¹ These results will have far reaching ...

Many medical researchers believe that it would be fruitless to submit for publication any paper that lacks statistical tests of significance. Their belief is not ill founded: editors and referees commonly rely on tests of significance as indicators of a ...

Fisher et al.¹ and Bonadonna et al.² have recently updated two major randomized studies investigating the role of surgical adjuvant chemotherapy in breast cancer. The former investigators used l-phenylalanine mustard (L-PAM), and the latter a regimen ...

No extract is available for articles shorter than 400 words.

To the Editor: Behan, Behan and Dick¹ recently reported an increased frequency of HLA-B8 in 14 adult patients with polymyositis and adduced it as evidence that the adult and childhood forms of polymyositis are variants of the same autoimmune process, ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We wish to challenge the conclusions as well as the assertions raised by Raskin and Unger in their article in the August 31 issue of the Journal.

First of all, regarding the effect of hyperglucagonemia on glucose regulation in insulin-...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Neutra et al., in the August 17 issue of the Journal, ignore the benefit of safety for the unborn patient during labor. The reduction in fetal deaths during labor is dismissed with the statement: "[since] few in utero deaths occur during ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

CONGRESSES ON ABORTION AND FERTILITY

The Indian Association of Fertility and Sterility and the United States International Foundation for Studies in Reproduction will present a congress on induced abortion and voluntary sterilization and a seminar on ...