DISABLING or lethal thromboembolic stroke is frequently preceded by less devastating ischemic events.^{1 , 2} These earlier episodes, whether transient or with residua and occurring in either the carotid or vertebrobasilar territories, indicate a poor ...

A LARGE literature deals with associations between social and behavioral characteristics and incidence or mortality from coronary heart disease,^{1 , 2} but studies of the influence of such factors on prognosis are sparse. An appropriate preoccupation with ...

PLASMA protein fraction is a solution of 5 per cent protein — largely albumin — used primarily for volume expansion in surgical patients.* In a prospective study reported in 1973, Bland and his co-workers documented the hypotensive effect of the solution ...

THE morbidity and mortality associated with untreated acute leukemia is, in large part, due to a failure of normal hematopoiesis. This disease can, in fact, be viewed as a neoplastic variant of aplastic anemia. The mechanisms underlying leukemia-induced ...

APPROXIMATELY half the total increase in medical expenditures during the 1960's was the result of increased utilization of medical services and not price inflation.¹ Most of these services are ordered on the patient's behalf by the physician, who has ...

"Essential" mixed cryoglobulinemia is characterized by dependent purpura, arthralgia and weakness and is frequently associated with glomerulonephritis.^{1 2 3 4 5 6 7} "Essential" or Type II² cryoglobulins are a mixture of monoclonal immunoglobulin (Ig) and ...

DISOPYRAMIDE (Norpace), a new antiarrhythmic agent with electrophysiologic properties similar to quinidine and possessing anticholinergic activity,¹ is effective in the suppression of ventricular and supraventricular tachyarrhythmias and ectopy with ...

Presentation of Case

First admission. A 78-year-old man was admitted to the hospital because of a pulmonary lesion.

He was well until four years earlier, when he began to have exertional angina pectoris, which progressed until it occurred on climbing one ...

Although surgically accessible carotid-artery atherothrombotic disease accounts for less than 15 per cent of all strokes, and atherothrombotic disease of large arteries including the carotid produces only 34 per cent of strokes, this group accounts for ...

From many directions we are reminded of the costs of social deprivation to individuals and society. Poorly educated and occupationally unskilled persons in an industrialized society are among its most deprived in their access to the necessities of life, ...

The enormous growth of knowledge of the kallikrein-kinin system has resulted from advances in the detailed protein chemistry of these proteolytic enzymes, cofactors and substrates. Equally important in the development of this understanding have been ...

DEATHS

Abernethy — George Lynn Abernethy, M.D., of Concord, died on March 17, 1977. He was in his 58th year.

Dr. Abernethy received his degree from Ohio State University College of Medicine in 1952.

Baker — Robert Ellsworth Baker, M.D., of Newport, Rhode ...

To the Editor: The serum anion gap (defined as the sodium concentration minus the sum of the chloride and bicarbonate concentrations) is often decreased in patients with multiple myeloma¹ or asymptomatic monoclonal gammopathy^{2 , 3} owing to the unmeasured ...

To the Editor: Recent correspondence in the Journal ¹ reported a serious toxic side effect from indomethacin given for Bartter's syndrome — namely, pseudotumor cerebri. This drug has other frequent undesirable side effects of headache and ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: A curious paradox seems to have crept into the field of surgical education in some quarters: teaching the actual technic of surgery has become déclassé. In contrast, the academic surgeon is widely admired for an ability to quote ...

To the Editor: Dr. Enthoven's vivisection, in the March 23 and 30 issues of the Journal, of the present medical financing system is accurate and perceptive. Unfortunately, his proposed reform, Consumer-Choice Health Plan, will not solve the problems he ...

FOLIC ACID AND THE NERVOUS SYSTEM

An international symposium entitled "Folic Acid and the Nervous System" will be held September 6–8 at the Hotel Loews La Cité in Montreal.

Further information may be obtained from the Organizing Committee, c/o Miss Diana ...