HUMAN growth hormone is known to alter tissue responsiveness to insulin. In clinical practice this effect is exemplified by a tendency to fasting hypoglycemia and augmented sensitivity to insulin in patients with isolated growth hormone deficiency,^{1 , 2} ...

THE transplantation of bone marrow between allogeneic HLA-identical siblings and between syngeneic siblings has been performed for the treatment of aplastic anemia and acute leukemia.^{1 , 2} Recently, autologous bone-marrow transplantations have been done ...

A DISCREPANCY has been noted between the rates of Down's syndrome diagnosed at amniocentesis and the rates that would be expected from observations in live births.¹ It has been suggested that a high rate of spontaneous fetal wastage of Down's syndrome ...

THE last decade has offered a fresh scenario for the lives of many of this nation's mentally retarded citizens. The dearth of health and rehabilitative services in public residential facilities caring for these persons was documented in litigation against ...

(First of Two Parts)

FIFTEEN years ago Laurell and Eriksson discovered a genetically determined deficiency in a major serum protease inhibitor.¹ They also noted a striking association between the deficiency and the early onset of severe emphysema. Five ...

IN this country, and, indeed, the world over, gastrointestinal cancer causes more deaths than cancer taking origin in any other organ system. Although management of these diseases has traditionally been considered the realm of the surgeon, there has not ...

THAT any disorder of the liver, infectious or non-infectious, may be associated with prolonged abnormal temperatures has been recognized for a long time. Although the clinical features of some of these conditions are not always specifically diagnostic, ...

THE carcinoid syndrome is characterized by episodes of flushing that appear to be secondary to the secretion of one or more substances by a tumor of enterochromaffin-cell origin.^{1 2 3} Flushing can be provoked pharmacologically by the administration of ...

AUTOTRANSPLANTATION of human parathyroid tissue into the forearm prevents hypoparathyroidism after total removal of parathyroid tissue from the neck.^{1 , 2} This procedure has been principally applied at the time of first operation in patients with ...

Presentation of Case

First admission. A 57-year-old woman was admitted to the hospital because of pain in the arm.

She was well until seven months previously, when she noticed pain in the left side of the chest on elevation of the arm; straining and ...

A newborn baby has survived powerful, natural selective forces. For example, only 75 per cent of four-week pregnancies conclude with a live birth.¹ From chromosomal analyses of spontaneous abortion products, we know that in early pregnancy there are ...

For an organ exposed to bacteria from both the systemic and portal circulations, it is surprising that bacterial infections of the liver are so rare. Although viral invasion of hepatic tissue is common, the extensive network of reticuloendothelial or von ...

It is now half a decade since the United States Government, acting in accordance with a new law, began to encourage the growth of Health Maintenance Organizations (HMO's) as an alternative to the traditional fee-for-service kind of medical care. In a ...

DEATHS

Downing — Virginia Chase Downing, M.D., of Lafayette, Colorado, died on January 2. She was in her 76th year.

Dr. Downing received her degree from Albany Medical College in 1943. She was a member of the American Medical Association.

Eliot — Martha ...

Scores of motorcyclists drove their motorcycles to the steps of the Massachusetts State House during the 1976–1977 legislative session to demand repeal of the Massachusetts helmet law. By confronting the lawmakers, concerned health professionals and the ...

No extract is available for articles shorter than 400 words.

To the Editor: In their report in the July 13 issue of the Journal ¹ Gamble and Ruggles discuss the syndrome of mixed cryoglobulinemia in a patient with chronic pulmonary coccidioidomycosis. They suggest that the pulmonary infection is responsible for ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In last week's issue of the Journal, Graze et al.¹ reported the results of a screening program for the early detection of familial medullary thyroid carcinoma. Since the submission of that manuscript, we have had the opportunity to study ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

This new standard reference textbook in the field of vascular surgery supersedes previous general textbooks on this subject. It is a timely contribution since the rapid emergence, development and standardization of diagnostic and therapeutic methods ...

Progress is the key word for this third volume which Dr. Jerzy Glass presents after an interval of seven years. There have been important advances in the field of gastroenterology in the intervening years, and the editor of this volume has very skillfully ...

No extract is available for articles shorter than 400 words.

Pain, deformity and disability of spinal origin are among the commonest complaints of patients consulting neurologic and orthopedic surgeons. These two surgical specialties have a long relation of interdisciplinary co-operation in the management of spinal-...

As hand surgery has evolved from a field of special interest into a recognized subspecialty, the challenge to compile a textbook that comprehensively covers the relevant subject matter has become increasingly difficult to meet.

Although the emphasis of ...

No extract is available for articles shorter than 400 words.

The medical community often has initial contact with the most serious cases of child abuse and neglect. Unfortunately, physicians and other practitioners are ill prepared to deal with the anger and sadness that these cases generate, and because they ...

Practice in the various medical professions is largely oriented toward the study of individuals, as it should be. Practice in the various statistical professions is almost entirely oriented toward the study of aggregates, so that the peculiarities of ...

This book reviews the development of drug regulatory legislation, the precipitating events and the consequences of each new law since the Biologics Control Act of 1902. Although written in a clear, easily readable, nontechnical style, it documents the ...

DIFFERENTIAL DIAGNOSIS AND PSYCHIATRY

Harvard Medical School and Massachusetts General Hospital will present a course entitled "Differential Diagnosis in Medical Psychiatry: Detecting Organic Disorders in Office Practice," November 17–19 at the Copley ...

No extract is available for articles shorter than 400 words.