INCREASED serum activities of enzymes normally found in muscle have been the biochemical hallmark for the diagnosis of muscular dystrophy and for the detection of carriers of X-linked Duchenne muscular dystrophy. Some investigators have postulated that ...

ONE of the most common clinical findings in women with elevated prolactin concentrations is reproductive dysfunction including oligomenorrhea or amenorrhea. Recent estimates suggest that as many as 15 to 20 per cent of nonpregnant amenorrheic patients ...

THEOPHYLLINE, at serum concentrations of 10 to 20 μg per milliliter, is an effective and safe drug for controlling the symptoms of chronic asthma.^{1 2 3} When elimination of theophylline is rapid, however, as is typical among children,⁴ excessive ...

ENROLLMENT in foreign medical schools by Americans is becoming increasingly popular. The Association of American Medical Colleges (AAMC) estimates (admittedly crude) of the numbers of such students have risen from 2800 in 1969¹ to 6000 currently.² ...

(Third of Three Parts)

Evaluation of New Therapies

To facilitate the application of the previously discussed assays of gelation, sickling and rheology to new drugs, the Sickle Cell Disease Branch of the National Heart, Lung, and Blood Institute is ...

MALIGNANT hypertension and rapid deterioration in renal function often occur in systemic scleroderma. Since medical therapy of this hypertension is frequently ineffective,^{1 2 3 4 5} and since the renal failure is considered irreversible,^{4 , 6 , 7} bilateral ...

RENAL disease is a frequent cause of death in scleroderma.^{1 2 3 4} Renal function can change either gradually or abruptly with the onset of a syndrome similar to malignant hypertension.⁴ This syndrome of severe uncontrolled hypertension and rapidly ...

ON June 30, 1978, the Massachusetts Appeals Court decided, in a case entitled "In the Matter of Shirley Dinnerstein,"¹ that the earlier Saikewicz ^{2 , 3} decision by the Massachusetts Supreme Judicial Court does not require prior judicial review and ...

Presentation of Case

A 28-year-old man was admitted to the hospital because of gastrointestinal bleeding.

The patient was well until five years earlier, when he sustained an abdominal injury in a motor-vehicle accident. The pyloric canal and liver were ...

IN this issue of the Journal, Pickard et al. report an exciting observation supporting the hypothesis that Duchenne muscular dystrophy is associated with membrane abnormalities in cells from tissues other than muscle. The abnormal capping observed in B ...

Progressive systemic sclerosis (diffuse scleroderma) is a disease of unknown cause characterized by widespread alterations of connective tissue, vascular lesions in many organs and by a variety of vasomotor abnormalities among which Raynaud's phenomenon ...

Some ads appearing frequently in the Sunday New York Times this year:

1. HOW TO GET INTO A FOREIGN MEDICAL, DENTAL OR VETERINARY SCHOOL. Openings available in accredited WHO-Listed Schools. Call or write to....

If you respond to this ad you learn about a "...

APPLICANTS FOR FELLOWSHIP

Published in Accordance with Chapter II, Section 2.301 of the Bylaws

Berkshire

Cohn, Michael Scott, 199 South Street, Pittsfield 01201. State University of New York Downstate Medical Center, 1973.

Frumkin, Michael Alan, 94 West ...

Trends in Births to Adolescents

Falling birthrates in the United States bring joy to the Malthusians and supporters of zero population growth, and fear to the administrators of the Social Security Trust Fund, to hospitals with underpopulated maternity ...

To the Editor: There is a curious inconsistency and lack of coherence in the paper by Aronow in the July 6 issue of the Journal. Three smokers consuming a total of 15 cigarettes in two hours would generate (in both mainstream and side stream smoke) about ...

To the Editor: The article by Seides et al.¹ was at first glance a welcomed addition to our understanding of the "long-term" course of patients after coronary-artery bypass grafts. It is encouraging to know that, on the basis of a study of 22 patients, ...

To the Editor: In their article, "Asymptomatic Structural Liver Disease in Hemophilia," which appeared in the June 22 issue of the Journal, Spero and his colleagues, using indirect immunofluorescence, presented data implicating the hepatitis B virus in ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Two family members have demonstrated adverse reactions to monosodium glutamate that include psychiatric symptoms not previously described in this syndrome.

My wife is a 38-year-old woman in good health with no previous history of ...

No extract is available for articles shorter than 400 words.

MEETING OF THE STUDY GROUP FOR STEROID HORMONES

The ninth meeting of the International Study Group for Steroid Hormones will be held in Rome this December.

The topics for discussion will include breast cancer, prostate cancer and ovarian function.

Further ...