SERUM cobalamin (vitamin B₁₂) levels measured by microbiologic assays with Euglena gracilis or Lactobacillus leichmannii are markedly reduced in cobalamin deficiency, but these assays require sterile technic, take one to seven days to perform and cannot ...

TRANSPLANTATION of cadaver kidneys has been successful in many patients with end-stage renal disease. The overall success rate, however, is substantially inferior to transplantation from living, related donors. Because of the natural limitation of ...

WE originally showed that patients who received kidney transplants without prior "immunization" with blood transfusions had a lower transplant survival rate than patients who were pre-treated with blood transfusions.¹ This paradoxical finding has now been ...

(Second of Three Parts)

Red Blood Cells

Contained within the normal erythrocyte is a 5 mM solution of hemoglobin, constituting 97.5 per cent of the cytoplasmic protein by weight.¹²¹ The other 2.5 per cent is primarily made up of protein systems that can ...

CLONAZEPAM, an antiepileptic drug approved in 1976 by the United States Food and Drug Administration (FDA) for treatment of certain types of seizures, is a benzodiazepine structurally related to chlordiazepoxide hydrochloride, diazepam and nitrazepam. Its ...

FOR the past 25 years, serum levels of cobalamin (vitamin B₁₂) have been determined reliably by means of microbiologic assays. These procedures, however, are time consuming and have been available in only a limited number of institutions. The development ...

Presentation of Case

A 70-year-old woman was admitted to the hospital because of fever and obtundation.

The patient was well and caring for a demented sister at home until six days earlier, when she began to feel weak and noticed a rise of the temperature ...

Two papers in this issue of the Journal will surely give pause to physicians who by and large have come to expect that a routinely ordered "serum B₁₂" will automatically tell them whether a patient is cobalamin deficient. Cooper and Whitehead report that ...

Francis Galton was sheltering from a brief summer shower in the grounds of Naworth Castle when suddenly the true nature of correlation flashed into his mind, and for a moment he forgot everything else in his "great delight."¹ Thus was the correlation ...

Under Public Law 93–641 state and local planning agencies make decisions regarding allocation of hospital resources. Hospital managers propose that their hospitals renovate or expand beds and install expensive equipment. The planning agencies respond to ...

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To the Editor: I should like to correct certain misleading inferences that may be drawn from Holmes's recent article¹ on genetic counseling, especially for Down's syndrome.

Holmes points out that in the past, one economic justification cited for making ...

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No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

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The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy and Histology

Cross-...

SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL

Seminars in Medicine of the Beth Israel Hospital will be held in the George Sherman Auditorium, Beth Israel Hospital, Boston, on the following Tuesdays at 4 p.m.

SEMINAR ON PEDIATRIC INFECTIOUS DISEASES

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