SEVERE aplastic anemia continues to be a devastating syndrome, of probable diverse causes, that often results in death within six months of diagnosis.^{1 , 2} Androgens and other hematinics are generally ineffective,^{2 3 4} and development of specific therapy ...

THE classification of human lymphoid-leukemia cells has recently been made more precise by the use of membrane-marker tests.^{1 2 3} These assays, in addition to being a valuable aid to diagnosis, have provided evidence of the likely cellular origin of some ...

PREVIOUS immunologic studies of follicular lymphoma have demonstrated that the nodules of lymphoma are composed of B lymphocytes.^{1 2 3 4 5} Most of these studies have used the detection of the receptor for the third component of complement (C3), which is ...

THE bland surface of a negative laboratory result may conceal information that helps to differentiate among possible diagnoses. The technic for extracting such information is quickly learned and easily applied.

Proposed Method of Analysis

In accordance ...

(Second of Three Parts)

Diagnosis of nongonococcal urethritis. One of the problems in dealing with nongonococcal urethritis is in establishing the diagnosis. Basically, it must currently be a diagnosis of exclusion, because routine diagnostic tests for ...

UNCOMMON in the 1950's, scabies has progressed in frequency since 1964 to epidemic proportions worldwide.^{1 2 3} In the United States scabies constitutes about 2 to 4 per cent of patients seen in dermatologists' offices.⁴ The socioeconomic characteristics ...

AFTER a delay of some 16 months, the Massachusetts Supreme Judicial Court has issued a full opinion concerning life-death decisions on patients.¹

The decision has caused great consternation among Massachusetts physicians and hospitals. Physicians ...

Presentation of Case

A 68-year-old woman was admitted to the hospital because of vomiting.

Seventeen months previously she entered the hospital because of a dry cough and painless erythematous lesions on the right lower extremity. Examination revealed ...

IN this issue of the Journal, Branda et al. report on a family in whom an inherited aplastic anemia, possibly preleukemic, is associated with a defect in folate metabolism. This family raises some interesting and puzzling questions. Why cannot cells from ...

IT is a fundamental canon of medical ethics that physicians should begin treatment only with the consent of the patient, except in emergencies, when they are expected to take appropriate lifesaving action on the patient's behalf even without consent. But ...

IT is time for medicine to dispose of the idea of "accident" and "accidental injury," so that recent halting steps in understanding the injury problem can continue. That such efforts merit high priority is emphasized by the fact that for persons one to 44 ...

No extract is available for articles shorter than 400 words.

To the Editor: Inaccuracies, if repeated often enough, particularly in major scientific journals, may become accepted as dogma. I am impelled, therefore, to challenge the opening statement of Dr. Rosen's editorial (N Engl J Med 297:1120–1121, 1977): "It ...

No extract is available for articles shorter than 400 words.

To the Editor: In a recent editorial, "VPB's — the Benign and the Malignant," Lesch¹ stated that in the setting of acute myocardial infarction, ventricular premature beats (VPB's) are the "harbinger" of higher-grade ventricular arrhythmias and "can ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The frontiers between various professional disciplines are remarkably interactive as each jurisdiction lends a helping or restraining hand to the activities of its professional neighbor. Ideals, concepts, sets of values, practical ...

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Social Topics

The Castrated ...

SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL

Seminars in Medicine of the Beth Israel Hospital will be held in the George Sherman Auditorium, Beth Israel Hospital, Boston, on the following Tuesdays at 4 p.m.

MANAGEMENT OF MUSCULOSKELETAL PROBLEMS

The ...