THE syndrome of inappropriate secretion of antidiuretic hormone has been of particular interest to clinicians, perhaps because of the appealing symmetry of the accompanying derangements in the composition of urine and plasma. In the presence of an ...

LITHIUM carbonate has been shown to cause neutrophilia in psychiatric patients,^{1 2 3 4} and considerable interest in its possible use in the treatment of neutropenia has therefore developed. Recent reports indicate that lithium treatment elevates the blood ...

THE annual world consumption of coffee exceeds four million tons. In some countries this amount translates into a per capita ingestion of 100 g of pure caffeine each year.¹ This figure is conservative, since substantial amounts of caffeine also occur in ...

(Second of Two Parts)

Clinical Correlations

Many of the features of myasthenia gravis that were previously poorly understood can now be explained satisfactorily in terms of the pathogenetic mechanisms outlined in the first part of this review. In this ...

THE most important nutrients affecting bone are vitamin D, calcium, and phosphorus.

Vitamin D

Vitamin D is obtained either from the diet or from endogenous production in the skin after exposure to ultraviolet light. Wavelengths capable of photoactivation ...

INTRAVAGINAL application of estrogen-containing creams has been widely used in the treatment of vaginal atrophy and related conditions due to estrogen deficiency. Although its efficacy is well recognized,^{1 , 2} the assumed "topical" effect and the ...

I HAVE to confess that the title of last month's contribution to this column ("Backward or For-ward?") could not have been more appropriate from a personal point of view because it was written as I made the journey from London to Sydney by the trans-...

PROLACTIN was discovered in 1928, as a lactogenic substance present in extracts of the pituitary gland of the cow. However, it is only since 1970 that this hormone has been definitely identified and measured in human blood. The long delay in its ...

Presentation of Case

A 77-year-old man was admitted to the hospital because of bleeding per rectum.

He was apparently well until two weeks before admission, when he experienced nausea, vomiting and persistent hiccupping. Five days before entry he passed ...

The syndrome of inappropriate secretion of antidiuretic hormone (ADH) was described by Schwartz and Bartter and their colleagues in 1957.¹ At that time is was clearly shown that the hyponatremia associated with this syndrome does not respond to sodium ...

However much we may wish it to, Laetrile is not about to disappear. Last May the Journal's editor expressed the exasperations of most physicians when he declared in these columns, "This Laetrile business is reaching the point of absurdity."¹ Yet since ...

Over a year ago, in response to growing public and professional interest in Laetrile, the National Cancer Institute indicated that it would consider conducting a Phase II clinical trial of the drug, given appropriate indications for such a trial. This ...

Although the ability of Laetrile to produce any therapeutic effect for the patient with cancer is highly questionable, there can be little doubt concerning the ability of this drug to produce a remarkable effect in the pages of the Journal. Within the ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Reconstitution of immunodeficient patients with fetal thymus or liver cells has been successful only occasionally; some may acquire capacity to reject allogeneic skin grafts but remain highly susceptible to infections.¹ Our findings in a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

PROGRAM ON THE DIAGNOSIS AND TREATMENT OF STROKE

The American Heart Association Greater Boston Division and the Massachusetts Rehabilitation Hospital will sponsor a program entitled "Topics in the Diagnosis and Treatment of Stroke" on Friday, February 10 ...

From agencies big and small throughout the government, the litany at the one-year mark of the Carter Administration is pretty much the same: the problems are worse than we realized, and correctives will take longer than we thought. The ebullience of last ...