THE high incidence of acute post-transfusion hepatitis with jaundice in hemophilic patients who have received many transfusions has been recognized for many years and was noted to rise with increased use of factor VIII and IX concentrates prepared from ...

THE routine screening of donor blood for the hepatitis B surface antigen (HBsAg, Australia antigen) has markedly decreased the incidence of post-transfusion, Type B hepatitis.^{1 2 3} Nevertheless, for reasons that are not clear, occasional cases still occur ...

THE use of tumor-specific antibodies for cancer detection or therapy has frequently been suggested.^{1 2 3 4} A specific antibody labeled with a radioisotope having appropriate gamma-emitting energy could detect neoplasms by external scintillation imaging ...

HETEROTOPIC autotransplantation of splenic tissue, or splenosis, may occur when cells, spilled from the pulp of the damaged spleen, become implanted on peritoneal surfaces and grow into visible nodules of splenic tissue. Splenosis has usually been a ...

(First of Two Parts)

THE mucosal lining of the intestinal tract is in a constant state of renewal. Enteric* epithelium has the fastest rate of turnover† for any tissue in the body, exceeded only by a few rapidly growing malignant tumors.¹ Nonetheless, ...

(Second of Two Parts)

Clinical Uses of Antiplatelet Drugs

The possibility that antiplatelet drugs may be useful in the prophylaxis or therapy of platelet-induced thromboembolism in man has aroused considerable interest in recent years. In addition, these ...

Presentation of Case

A 55-year-old woman was admitted to the hospital because of anemia.

She was well until three months earlier, when she experienced the insidious onset of weakness, malaise and exertional dyspnea. One month later she began to hear ...

The good news is that the average patient requiring a transfusion today has a lower probability of contracting hepatitis from it than in previous years. The bad news is that technologic gains in the ability to identify infective donors have increased ...

The fascinating observation of Pearson and his coworkers, in this issue of the Journal, that traumatized spleen tissue may regrow (or be "reborn") into splenules after its spillage into the peritoneal cavity can probably be explained by the phenomenon of ...

One Step Forward — Two Steps Back

There is a tide in the affairs of men that — taken at the flood — can sweep them out to sea. The tide of "mandatory continuing medical education" is in full developmental surge. What began as a relatively small stimulus, ...

It has become accepted medical practice to inform pregnant women 35 years of age and older of their increased risk of having a child with chromosome abnormality in comparison to younger women, and to offer prenatal diagnosis to determine whether the fetus ...

No extract is available for articles shorter than 400 words.

To the Editor: The recent paper by Broder et al.¹ and the accompanying editorial² described new insights gained through the sophisticated investigation of a T-cell acute lymphocytic leukemia. We now present a multidisciplinary study of cells from a ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: Chesney et al. are to be congratulated on their recent excellent article, "Increased Growth after Long-Term Oral 1α,25-Vitamin D₃ in Childhood Renal Osteodystrophy," which appeared in the February 2 issue of the Journal. Of particular ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

Let's trace the legislative path of a relatively minor health-care amendment recently adopted by the Congress. The exercise not only illustrates the intricacies and peculiarities of the legislative process but also foreshadows the immense battles to come ...