INTERFERON, a naturally occurring host defense against viral disease, is active in preventing or modifying viral disease in a number of animal models,¹ in local prophylaxis of respiratory viral infections² and in therapy of herpes keratitis.³ In addition, ...

VON Willebrand's disease is an inherited bleeding disorder characterized by a proportional reduction in the circulating blood of factor VIII (antihemophilic factor) procoagulant activity (VIII_AHF), factor-VIII-related antigen (VIII_AGN) and von Willebrand ...

INHIBITION of the renin-angiotensin system has found increasing use as a diagnostic or therapeutic measure in hypertension. Two compounds have found clinical application: the competitive antagonist of angiotensin II, saralasin (or P-113), and the ...

VITAMIN-D-dependent rickets is characterized by clinical and biochemical features of rickets that occur despite an adequate intake of vitamin D and can be entirely reversed by pharmacologic doses of vitamin D.^{1 2 3} Recent evidence suggests that the basic ...

EXCESS parathyroid hormone has been reported to be responsible for abnormalities attributed to the long-sought-for toxic factor of uremia.^{1 , 2} Uremic patients have elevated parathormone in their blood because of increased secretion from hyperplastic ...

BECAUSE of the prevalent assumption that all Plato's dialogues were known to scholars from the time of the Academy, the recent discovery of the "Categorica" scroll has sparked unprecedented controversy among experts. Its authenticity has been challenged ...

SUDDEN death in adults without serious underlying heart disease has emerged as a major complication of the liquid protein diets.^{1 , 2} Fifteen such cases have been reported to the Center for Disease Control and the Food and Drug Administration since July 1,...

IN the great turmoil in Massachusetts over the Saikewicz case¹ in the past few months, little attention has been paid to another landmark, historically important medicolegal decision passed down by the same high court just before this case. In this ...

THERE is a substantial minority of people whose body weights are considerably in excess both of average values and, more important, of values that are appropriate for good health. Interest in them, and in the basic processes underlying maintenance of body ...

Presentation of Case

A 44-year-old electrician from Nantucket was admitted to the hospital because of hemoptysis and renal failure.

He was well until seven years earlier, when he had an anterolateral myocardial infarct. He recovered except for occasional ...

Twenty-one years after the discovery of interferon,¹ Merigan et al., in this issue of the Journal, provide convincing evidence for its effectiveness in man. In well controlled double-blind trials, leukocyte interferon reduced dissemination of cutaneous ...

Renin has been studied for a very long time, but only recently has it emerged from the status of an experimental curiosity to that of a hormone centrally involved in blood-pressure homeostasis. Unlike the products of other endocrine organs, which may be ...

Recent reports from the Food and Drug Administration and Center for Disease Control have alerted the medical community to sudden death occurring in patients treated for obesity with low calorie liquid protein diets.¹ A detailed report of one of these ...

COMMITTEE ON MATERNAL WELFARE

Eclampsia and Pulmonary Insufficiency

An unmarried 15-year-old gravida 1 completely concealed her unwanted pregnancy until found at home during a convulsive seizure at 33 weeks' gestation. On admission to the hospital, the ...

No extract is available for articles shorter than 400 words.

To the Editor: Nationwide publicity about plasmapheresis therapy for myasthenia gravis, following upon the article by Dau et al.,¹ requires that several points be strongly emphasized to physicians trying to deal with the resultant expectations of ...

No extract is available for articles shorter than 400 words.

To the Editor: Dr. Hiatt's editorial, "Lessons of the Coronary-Bypass Debate," in the December 29, 1977, issue of the Journal, seems to be based on an assumption that we have done something wrong in applying the operation to many patients with angina. He ...

No extract is available for articles shorter than 400 words.

To the Editor: The Katzel and Baltins letter on medical complications of jogging, in the February 16 issue of the Journal, mentions a variety of dangers of this popular sport. A more worrisome complication might be included in the lengthy list of adverse ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: The recent article by Halushka et al.¹ on the behavior of platelets in diabetic patients and the accompanying editorial² are reinforced by the following case, in which a protracted course of necrobiosis lipoidica diabeticorum responded ...

To the Editor: As recently emphasized in the Journal,¹ the relation between partial lipodystrophy, membranoproliferative glomerulonephritis of the dense-deposit type and chronic activation of the alternative complement pathway by C3 nephritic factor is ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: We recently took care of a patient with an extremely high serum chloride concentration and a negative anion gap. We considered this abnormality secondary to high serum iodide, a cause not mentioned in recent reviews.^{1 , 2}

The patient was ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: At about the time Jukes¹ reminded us that nitrite is commonly present in saliva, it was reported² that certain groups had petitioned the United States Department of Agriculture to ban nitrites, such as sodium nitrite, as additive ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: In our letter to the Editor in the February 9 issue about the neutering of English several faulty editorial changes were made. The singular verb "has" in our manuscript was changed to the plural "have" in the sentence: "To date, none of ...

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The first part of this good book deals with cardiac-emergency syndromes, including Dr. Wheat's chapter on acute dissecting aneurysms of the aorta. The second part discusses apparatus used for cardiac emergencies, and the third deals with drugs used for ...

This book is not one that would ordinarily be reviewed in a serious journal. If it had been presented as a piece of science fiction it would have been just one more clever novel about future scientific manipulation of human beings. Yet the author insists ...

SURGICAL ASPECTS OF INFERTILITY

The Long Island Jewish-Hillside Medical Center will present a program entitled "Surgical Aspects of Infertility" at the Jewish Institute for Geriatric Care in New Hyde Park, May 24. The fee is $45.

Further information may ...

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