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April 27, 1978  Vol. 298 No. 17

Original Articles
921-927

THE Wiskott-Aldrich syndrome is a genetically determined X-linked disorder in which affected males have abnormal cellular immunity, decreased platelet survival, abnormal platelet function, eczema and decreased antibody response to carbohydrate antigens.1 ...

927-933

THE hemolytic-uremic syndrome was described by Gasser et al.1 as the association of hemolytic anemia, thrombocytopenia and acute renal failure, and is one of the most common causes of acute renal failure in childhood in some regions of the world.2 ...

934-939

    THE chest roentgenogram may be normal in such disorders as asthma, chronic bronchitis and sometimes emphysema, since the radiograph represents a static image and is an insensitive indicator of airflow obstruction. In the infiltrative diseases, however, it ...

    Special Article
    940-950

    DURING the past decade, an unusual symbiotic relation that has linked the government and academic medical centers in a highly productive venture has begun to come apart. This special partnership, which gradually evolved in the years immediately after ...

    Medical Intelligence
    951-953

    CYTOMEGALOVIRUS infection is extremely common after renal transplantation, with evidence of infection in as many as 90 per cent1 to 96 per cent2 of patients. Although many recipients excrete the virus in their urine or saliva for months or years with no ...

    954-955

    LARGE areas of Manhattan are afloat. I remember when the new Bellevue was being built, 15 years ago; the first stage was the most spectacular and satisfying, an enormous square lake. It was there for two years, named Lake Bellevue, while the disconsolate ...

    955-956

    FOR many years one of the most intractable problems of the National Health Service (NHS) has been the long time that some patients may have to wait for hospital outpatient consultations and the further delay before operations can be performed on those ...

    Case Records of the Massachusetts General Hospital
    957-962

    Presentation of Case

    A 44-year-old man was admitted to the hospital because of diarrhea.

    The patient was a chronic alcoholic who began to drink at the age of 16 years and had consumed alcohol in large amounts since the age of 25 years. Six months earlier ...

    Editorials
    963-964

    It was first shown in rodents that the use of a marrow-graft donor matched at the major histocompatibility complex reduced the incidence and severity of graft-versus-host disease and considerably increased the likelihood of long-term survival of the ...

    964-966

      The article in this week's issue of the Journal by Koster and his colleagues raises important questions not only about the pathogenesis of the hemolytic-uremic syndrome but, perhaps more importantly, about the clinical conditions that can reasonably be ...

      966-967

        Although the massively publicized swine-influenza experience has given Americans a lesson on the fallibility of immunization policy decisions, we have been spared much of another disturbing debate now raging in Europe. Pertussis vaccine, which must be ...

        967-968

        No extract is available for articles shorter than 400 words.

        Massachusetts Medical Society
        968-969

        197th ANNIVERSARY MEETING

        May 22 (evening), May 23 and 24, 1978 Howard Johnson's 57 Complex, 200 Stuart Street, Boston

        AN ILLUSION OF HEALTH —MALNUTRITION IN HOSPITAL AND HOME CURRENT CONCEPTS IN RECONSTRUCTIVE SURGERY

        MONDAY EVENING — SECTION DINNERS (...

        Correspondence
        970

        No extract is available for articles shorter than 400 words.

        972-973

        No extract is available for articles shorter than 400 words.

        973-974

        No extract is available for articles shorter than 400 words.

        974-975

        No extract is available for articles shorter than 400 words.

        975

        To the Editor: The following report demonstrates electrocardiographic abnormalities secondary to disopyramide that resemble quinidine effects: prolongation of QRS complex, lengthening of Q-T interval and prominent U waves. Ventricular fibrillation ...

        975-976

        No extract is available for articles shorter than 400 words.

        976

        No extract is available for articles shorter than 400 words.

        977

        No extract is available for articles shorter than 400 words.

        977

        No extract is available for articles shorter than 400 words.

        Notices
        978

        THE GENETICS OF CANCER

        The National Foundation-March of Dimes, Albert Einstein College of Medicine, the Brookdale Hospital Medical Center, Columbia University College of Physicians and Surgeons and Mount Sinai School of Medicine will present a symposium ...

        Correction
        978

        No extract is available for articles shorter than 400 words.

        Washington Report
        979-980

        Congress now has before it what HEW Secretary Joseph Califano describes as "the first complete overhaul of the basic Federal law regulating drugs since 1938...and the first major change since 1962."

        Entitled the Drug Regulation Reform Act of 1978, it was ...

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