CHEDIAK-Higashi disease is a rare familial disorder characterized by partial oculocutaneous albinism, photophobia and severe recurrent infections.¹ Neutrophils from these patients are deficient in chemotactic² and bactericidal activities,³ and there is ...

HYPOPITUITARISM in childhood is usually associated with a normal or small sella turcica. In the series of 34 hypopituitary children reported by Underwood et al.¹ all had sellar volumes below the mean, and 11 had volumes below the third percentile for age. ...

BEEM and Saxon¹ recently linked the presence of nasopharyngeal Chlamydia trachomatis, the etiologic agent of trachoma,² inclusion conjunctivitis³ and a portion of nongonococcal urethritis,⁴ to a pneumonitis syndrome of infancy. They described the ...

IN the first part of this article, which appeared last week, I reviewed the causes of inflation in health-care costs and the inequities in financing today, explained why direct economic regulations will not make things better and reviewed the limitations ...

(Second of Two Parts)

Inherited Abnormalities of the Oxygen-Dependent Killing Mechanisms of Phagocytes

Studies over the past 15 years have disclosed a number of inherited conditions in which there is a deficiency in one or another of the enzymes involved ...

THE report of the Organization for Economic Co-operation and Development (OECD)¹ on public expenditure on health, published last year, contains a great deal of statistical information about the pattern of spending on health care by the member countries ...

Presentation of Case

First admission. A 67-year-old woman was admitted to the hospital because of Wegener's granulomatosis.

She was well until three and a half months earlier, when she began to have pleuritic pain, malaise, anorexia and a sensation of ...

National health insurance (NHI) legislation has been waiting in the wings ever since Medicare and Medicaid first made their appearance over a decade ago. Numerous bills have been introduced in both houses of Congress, although none has yet generated wide ...

Noninvasive diagnostic or creening technics have obvious appeal. When such approaches in pregnancy yield important information about fetal health, the vigor with which they will be pursued can easily be anticipated. This situation has been noted since the ...

In the 1960's there was concern of an impending physician shortage in the United States. It was recognized that segments of the population, particularly in rural and inner-city areas, were receiving inadequate health care.

The American Academy of ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

To the Editor: I read with interest the paper describing an abnormality of the thiamine-requiring enzyme, transketolase, in patients with the Wernicke-Korsakoff syndrome (N Engl J Med 297:1367–1370, 1977). The authors do not specify the time of skin ...

No extract is available for articles shorter than 400 words.

To the Editor: Because the 90 per cent frequency of HLA-B27 in whites with ankylosing spondylitis (AS) declines significantly in other populations with AS (75 per cent in non-Ashkenazi Jews,¹ 67 per cent in Japanese² and 48 per cent in American blacks³), ...

No extract is available for articles shorter than 400 words.

To the Editor: Leon Eisenberg 's cautionary editorial on "The Perils of Prevention" (N Engl J Med 297:1230–1232, 1977) sheds more heat than light on the important issue of preventive medicine. By adroitly identifying proponents of prevention with ...

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

No extract is available for articles shorter than 400 words.

The receipt of the following books is acknowledged, and this listing must be regarded as sufficient return for the courtesy of the sender. Books that appear to be of particular interest will be reviewed as space permits.

Anatomy and Histology

The ...

THE LUCIAN AWARD

McGill University is seeking nominees for the first Louis and Artur Lucian Award for research in circulatory diseases. A scientific investigator who has made an outstanding contribution to this field will be named Visiting Professor for ...