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March 23, 1978  Vol. 298 No. 12

Original Articles
637-642

FROZEN-deglycerolized red blood cells have many potential advantages over other red-cell products, including prolonged storage time, improved blood inventory control, maintenance of rare-donor blood, reduced risk of febrile, nonhemolytic transfusion ...

643-647

The conventional treatment of thyrotoxicosis in the younger patient is a course of antithyroid drugs given for 12 to 18 months in the hope that the disease will have entered remission by the time therapy is discontinued. Antithyroid drugs, such as ...

647-650

PERNICIOUS anemia predominates in people of northern European origin.1 Yet surveys in racial groups in whom this disease was widely regarded as rare, such as American blacks and American Indians, suggest an incidence in them higher than has been assumed.2 ...

Special Article
650-658

(First of Two Parts)

HEADLINES will soon appear proclaiming the latest round of health-care cost increases. The nation's health-care spending exceeded $160 billion in 1977 — four times the 1965 amount. Congress will consider cost-control measures with ...

Medical Progress
659-668

(First of Two Parts)

THE part played by phagocytes in defense against invading pathogens has been recognized since 1883. In that year, Metschnikoff, a Russian zoologist, reported that foreign particles injected into metazoans (in Metschnikoff's ...

Medical Intelligence
669-670

THE α-thalassemias in Asian populations are primarily caused by deletion of the α-globin structural genes.1 2 3 4 5 6 In the fatal condition of homozygous α-thalassemia associated with hydrops fetalis, all four normally present α-globin structural genes ...

670-671

MECHANICAL circulatory support with the intra-aortic balloon has permitted preoperative evaluation of patients in low-output cardiac failure.1 2 3 Such studies show surgically correctable problems in many cases, and temporary assistance with the intra-...

Case Records of the Massachusetts General Hospital
672-678

Presentation of Case

A 52-year-old man was admitted to the hospital because of melena.

He was well until three days earlier, when he began to experience a "queasy" sensation. On the following day he felt weak and observed that his stools were dark. Two ...

Editorials
679-681

    Since its outgrowth from studies on freezing vinegar eels and spermatozoa over 25 years ago, cryopreservation of human red blood cells (RBC) has progressed considerably. The labors of transfusionists, physical chemists and bioengineers have brought forth ...

    681-682

    Several forms of therapy are available for the treatment of hyperthyroidism, and judicious use of each is usually accompanied by gratifying relief of symptoms and restoration of the euthyroid state. What factors should be considered in the selection of ...

    682-684

    More than 10 years have passed since the first successful human heart transplantation.1 After an initial flurry of excitement, and widespread trial in many centers, recurrent failures led to disillusionment and virtual abandonment of the procedure, in all ...

    Massachusetts Medical Society
    684-686

    APPLICANTS FOR FELLOWSHIP

    Published in Accordance with Chapter II, Section 2.301 of the Bylaws

    Barnstable

    Bouche, Paul Robert, 121 Locust Street, Falmouth 02540. St. Louis University School of Medicine, 1970.

    Gorman, Gerald P., 49 Gigson Road, Orleans ...

    Correspondence
    686-687

    To the Editor: Two conflicting reports have appeared in the Journal regarding the role of aryl hydrocarbon hydroxylase (AHH) induction in predisposing to bronchogenic carcinoma. Kellermann et al.1 have suggested that there is genetic variation of AHH in ...

    687

    To the Editor: Nonketotic hyperglycemia (NKH) is a disease identified clinically with respiratory distress, muscular hypotonia, myoclonic seizures, vomiting and extreme lethargy. The outcome is almost invariably poor, and early infant deaths are ...

    687-688

    To the Editor: We have investigated the role of the vitamin-D-binding protein (group-specific component, Gc)1 in the cause of two disorders of calcium metabolism.

    The Williams syndrome (WS) is a congenital disorder characterized by mental and mild growth ...

    688-689

    To the Editor: The association between viral infection and Parkinson's disease (PD) has been of interest ever since the relation was suggested between the development of this condition and the pandemic of encephalitis lethargica. This viral origin has ...

    689

    No extract is available for articles shorter than 400 words.

    Notices
    689-690

    COURSES FROM NEW YORK UNIVERSITY MEDICAL SCHOOL

    New York University Post-Graduate Medical School will present the following courses during the coming months: "Environmental Health," March 27-April 7; "Clinical Cardiology for the Practicing Physician," ...

    Washington Report
    691-692

      Since, as someone long ago observed, the business of the press is fights and forecasts, the medical profession might easily assume that Washington rings with controversies concerning health care and related matters. There is an impressive yardage of ...

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